Lineage-specific silencing of PSAT1 induces serine auxotrophy and sensitivity to dietary serine starvation in luminal breast tumors

por Choi, Bo-Hyun, Rawat, Vipin, Högström, Jenny, Burns, Philippa A., Conger, Kelly O., Ozgurses, Mete Emir, Patel, Jaymin M., Mehta, Tejas S., Warren, Angelica, Selfors, Laura M., Muranen, Taru, Coloff, Jonathan L.
Publicado 2022

ASCT2 is the primary serine transporter in cancer cells

por Conger, Kelly O., Chidley, Christopher, Ozgurses, Mete Emir, Zhao, Huiping, Kim, Yumi, Semina, Svetlana E., Burns, Philippa, Rawat, Vipin, Sheldon, Ryan, Ben-Sahra, Issam, Frasor, Jonna, Sorger, Peter K., DeNicola, Gina M., Coloff, Jonathan L.
Publicado 2023

Drug screening in human physiologic medium identifies uric acid as an inhibitor of rigosertib efficacy

por Rawat, Vipin, DeLear, Patrick, Prashanth, Prarthana, Ozgurses, Mete Emir, Tebeje, Anteneh, Burns, Philippa A., Conger, Kelly O., Solís, Christopher, Hasnain, Yasir, Novikova, Anna, Endress, Jennifer E., González-Sánchez, Paloma, Dong, Wentao, Stephanopoulos, Greg, DeNicola, Gina M., Harris, Isaac S., Sept, David, Mason, Frank M., Coloff, Jonathan L.
Publicado 2023