Identification of potential new treatment response markers and therapeutic targets using a Gaussian process-based method in lapatinib insensitive breast cancer models

por Santra, Tapesh, Roche, Sandra, Conlon, Neil, O’Donovan, Norma, Crown, John, O’Connor, Robert, Kolch, Walter
Publicado 2017

Preclinical Characteristics of the Irreversible Pan-HER Kinase Inhibitor Neratinib Compared with Lapatinib: Implications for the Treatment of HER2-Positive and HER2-Mutated Breast...

por Collins, Denis M., Conlon, Neil T., Kannan, Srinivasaraghavan, Verma, Chandra S., Eli, Lisa D., Lalani, Alshad S., Crown, John
Publicado 2019

HER2-Targeted Tyrosine Kinase Inhibitors Cause Therapy-Induced-Senescence in Breast Cancer Cells

por McDermott, Martina S. J., Conlon, Neil, Browne, Brigid C., Szabo, Adam, Synnott, Naoise C., O’Brien, Neil A., Duffy, Michael J., Crown, John, O’Donovan, Norma
Publicado 2019

Correction: PP2A inhibition overcomes acquired resistance to HER2 targeted therapy

por McDermott, Martina S. J., Browne, Brigid C., Conlon, Neil T., O’Brien, Neil A., Slamon, Dennis J., Henry, Michael, Meleady, Paula, Clynes, Martin, Dowling, Paul, Crown, John, O’Donovan, Norma
Publicado 2023

PP2A inhibition overcomes acquired resistance to HER2 targeted therapy

por McDermott, Martina SJ, Browne, Brigid C, Conlon, Neil T, O’Brien, Neil A, Slamon, Dennis J, Henry, Michael, Meleady, Paula, Clynes, Martin, Dowling, Paul, Crown, John, O’Donovan, Norma
Publicado 2014

Comparative analysis of drug response and gene profiling of HER2-targeted tyrosine kinase inhibitors

por Conlon, Neil T., Kooijman, Jeffrey J., van Gerwen, Suzanne J. C., Mulder, Winfried R., Zaman, Guido J. R., Diala, Irmina, Eli, Lisa D., Lalani, Alshad S., Crown, John, Collins, Denis M.
Publicado 2021

Preclinical evaluation of Insulin-like growth factor receptor 1 (IGF1R) and Insulin Receptor (IR) as a therapeutic targets in triple negative breast cancer

por Roche, Sandra, Gaule, Patricia, Winrow, Deirdre, Mukherjee, Nupur, O’Neill, Fiona, Conlon, Neil T., Meiller, Justine, Collins, Denis M., Canonici, Alexandra, Fawsi, Mohammed Ibrahim, Estepa-Fernández, Alejandra, Madden, Stephen F., Crown, John, O’Donovan, Norma, Eustace, Alex J.
Publicado 2023

Combined targeting EGFR and SRC as a potential novel therapeutic approach for the treatment of triple negative breast cancer

por Canonici, Alexandra, Browne, Alacoque L., Ibrahim, Mohamed F. K., Fanning, Kevin P., Roche, Sandra, Conlon, Neil T., O’Neill, Fiona, Meiller, Justine, Cremona, Mattia, Morgan, Clare, Hennessy, Bryan T., Eustace, Alex J., Solca, Flavio, O’Donovan, Norma, Crown, John
Publicado 2020

Could MicroRNAs Be Useful Tools to Improve the Diagnosis and Treatment of Rare Gynecological Cancers? A Brief Overview

por Di Fiore, Riccardo, Suleiman, Sherif, Pentimalli, Francesca, O’Toole, Sharon A., O’Leary, John J., Ward, Mark P., Conlon, Neil T., Sabol, Maja, Ozretić, Petar, Erson-Bensan, Ayse Elif, Reed, Nicholas, Giordano, Antonio, Herrington, C. Simon, Calleja-Agius, Jean
Publicado 2021

A Comparative Quantitative LC-MS/MS Profiling Analysis of Human Pancreatic Adenocarcinoma, Adjacent-Normal Tissue, and Patient-Derived Tumour Xenografts

por Coleman, Orla, Henry, Michael, O’Neill, Fiona, Roche, Sandra, Swan, Niall, Boyle, Lorraine, Murphy, Jean, Meiller, Justine, Conlon, Neil T., Geoghegan, Justin, Conlon, Kevin C., Lynch, Vincent, Straubinger, Ninfa L., Straubinger, Robert M., McVey, Gerard, Moriarty, Michael, Meleady, Paula, Clynes, Martin
Publicado 2018

Establishment and Characterisation by Expression Microarray of Patient-Derived Xenograft Panel of Human Pancreatic Adenocarcinoma Patients

por Roche, Sandra, O’Neill, Fiona, Murphy, Jean, Swan, Niall, Meiller, Justine, Conlon, Neil T., Geoghegan, Justin, Conlon, Kevin, McDermott, Ray, Rahman, Rozana, Toomey, Sinead, Straubinger, Ninfa L., Straubinger, Robert M., O’Connor, Robert, McVey, Gerard, Moriarty, Michael, Clynes, Martin
Publicado 2020

Alteration in Levels of Specific miRNAs and Their Potential Protein Targets between Human Pancreatic Cancer Samples, Adjacent Normal Tissue, and Xenografts Derived from These Tumor...

por O’Neill, Fiona, Allen-Coyle, Taylor-Jade, Roche, Sandra, Meiller, Justine, Conlon, Neil T., Swan, Niall, Straubinger, Robert M., Geoghegan, Justin, Straubinger, Ninfa L., Conlon, Kevin, McDermott, Ray, O’Sullivan, Finbarr, Henry, Michael, Meleady, Paula, McVey, Gerard, O’Connor, Robert, Moriarty, Michael, Clynes, Martin
Publicado 2023

Development of acquired resistance to lapatinib may sensitise HER2-positive breast cancer cells to apoptosis induction by obatoclax and TRAIL

por Eustace, Alex J, Conlon, Neil T, McDermott, Martina S J, Browne, Brigid C, O’Leary, Patrick, Holmes, Frankie A, Espina, Virginia, Liotta, Lance A, O’Shaughnessy, Joyce, Gallagher, Clair, O’Driscoll, Lorraine, Rani, Sweta, Madden, Stephen F, O’Brien, Neil A, Ginther, Charles, Slamon, Dennis, Walsh, Naomi, Gallagher, William M, Zagozdzon, Radoslaw, Watson, William R, O’Donovan, Norma, Crown, John
Publicado 2018

GYNOCARE Update: Modern Strategies to Improve Diagnosis and Treatment of Rare Gynecologic Tumors—Current Challenges and Future Directions

por Di Fiore, Riccardo, Suleiman, Sherif, Ellul, Bridget, O’Toole, Sharon A., Savona-Ventura, Charles, Felix, Ana, Napolioni, Valerio, Conlon, Neil T., Kahramanoglu, Ilker, Azzopardi, Miriam J., Dalmas, Miriam, Calleja, Neville, Brincat, Mark R., Muscat-Baron, Yves, Sabol, Maja, Dimitrievska, Vera, Yordanov, Angel, Vasileva-Slaveva, Mariela, von Brockdorff, Kristelle, Micallef, Rachel A., Kubelac, Paul, Achimas-Cadariu, Patriciu, Vlad, Catalin, Tzortzatou, Olga, Poka, Robert, Giordano, Antonio, Felice, Alex, Reed, Nicholas, Herrington, C. Simon, Faraggi, David, Calleja-Agius, Jean
Publicado 2021