Genome Wide Mapping of NR4A Binding Reveals Cooperativity with ETS Factors to Promote Epigenetic Activation of Distal Enhancers in Acute Myeloid Leukemia Cells

por Duren, Ryan P., Boudreaux, Seth P., Conneely, Orla M.
Publicado 2016

Reprogramming of the estrogen responsive transcriptome contributes to tamoxifen-dependent protection against tumorigenesis in the p53 null mammary epithelial cells

por Palaniappan, Murugesan, Edwards, David, Creighton, Chad J., Medina, Daniel, Conneely, Orla M.
Publicado 2018

Nuclear Receptor 4a3 (Nr4a3) Regulates Murine Mast Cell Responses and Granule Content

por Garcia-Faroldi, Gianni, Melo, Fabio R., Bruemmer, Dennis, Conneely, Orla M., Pejler, Gunnar, Lundequist, Anders
Publicado 2014

Progesterone receptors - animal models and cell signaling in breast cancer: Progesterone's role in mammary gland development and tumorigenesis as disclosed by experimental mouse ge...

por Soyal, Selma, Ismail, Preeti M, Li, Jie, Mulac-Jericevic, Biserka, Conneely, Orla M, Lydon, John P
Publicado 2002

Drug Targeting of NR4A Nuclear Receptors for Treatment of Acute Myeloid Leukemia

por Boudreaux, Seth P., Duren, Ryan P., Call, Steven G., Nguyen, Loc, Freire, Pablo R, Narayanan, Padmini, Redell, Michele S., Conneely, Orla M.
Publicado 2018

Targeting Oncogenic Super Enhancers in MYC-Dependent AML Using a Small Molecule Activator of NR4A Nuclear Receptors

por Call, S. Greg, Duren, Ryan P., Panigrahi, Anil K., Nguyen, Loc, Freire, Pablo R., Grimm, Sandra L., Coarfa, Cristian, Conneely, Orla M.
Publicado 2020

Bone marrow NR4A expression is not a dominant factor in the development of atherosclerosis or macrophage polarization in mice

por Chao, Lily C., Soto, Erin, Hong, Cynthia, Ito, Ayaka, Pei, Liming, Chawla, Ajay, Conneely, Orla M., Tangirala, Rajendra K., Evans, Ronald M., Tontonoz, Peter
Publicado 2013

Estradiol Preferentially Induces Progestin Receptor-A (PR-A) Over PR-B in Cells Expressing Nuclear Receptor Coactivators in the Female Mouse Hypothalamus1,2,3

por Acharya, Kalpana D., Finkelstein, Sarah D., Bless, Elizabeth P., Nettles, Sabin A., Mulac-Jericevic, Biserka, Conneely, Orla M., Mani, Shaila K., Tetel, Marc J.
Publicado 2015

Nuclear receptor NR4A1 is a tumor suppressor down-regulated in triple-negative breast cancer

por Wu, Hongmei, Bi, Jiong, Peng, Yan, Huo, Lei, Yu, Xiaobin, Yang, Zhihui, Zhou, Yunyun, Qin, Li, Xu, Yixiang, Liao, Lan, Xie, Yang, Conneely, Orla M., Jonkers, Jos, Xu, Jianming
Publicado 2017