Structural Determinants of Oligomerization of the Aquaporin-4 Channel

por Kitchen, Philip, Conner, Matthew T., Bill, Roslyn M., Conner, Alex C.
Publicado 2016

Aquaporins and Their Regulation after Spinal Cord Injury

por Halsey, Andrea M., Conner, Alex C., Bill, Roslyn M., Logan, Ann, Ahmed, Zubair
Publicado 2018

Inhibitors of Mammalian Aquaporin Water Channels

por Abir-Awan, Mohammed, Kitchen, Philip, Salman, Mootaz M., Conner, Matthew T., Conner, Alex C., Bill, Roslyn M.
Publicado 2019

Plasma Membrane Abundance of Human Aquaporin 5 Is Dynamically Regulated by Multiple Pathways

por Kitchen, Philip, Öberg, Fredrik, Sjöhamn, Jennie, Hedfalk, Kristina, Bill, Roslyn M., Conner, Alex C., Conner, Matthew T., Törnroth-Horsefield, Susanna
Publicado 2015

Transcriptome Analysis of Gene Expression Provides New Insights into the Effect of Mild Therapeutic Hypothermia on Primary Human Cortical Astrocytes Cultured under Hypoxia

por Salman, Mootaz M., Kitchen, Philip, Woodroofe, M. Nicola, Bill, Roslyn M., Conner, Alex C., Heath, Paul R., Conner, Matthew T.
Publicado 2017

Hypothermia increases aquaporin 4 (AQP4) plasma membrane abundance in human primary cortical astrocytes via a calcium/transient receptor potential vanilloid 4 (TRPV4)‐ and calmodul...

por Salman, Mootaz M., Kitchen, Philip, Woodroofe, M. Nicola, Brown, James E., Bill, Roslyn M., Conner, Alex C., Conner, Matthew T.
Publicado 2017

Identification and Molecular Mechanisms of the Rapid Tonicity-induced Relocalization of the Aquaporin 4 Channel

por Kitchen, Philip, Day, Rebecca E., Taylor, Luke H. J., Salman, Mootaz M., Bill, Roslyn M., Conner, Matthew T., Conner, Alex C.
Publicado 2015

Calcein Fluorescence Quenching to Measure Plasma Membrane Water Flux in Live Mammalian Cells

por Kitchen, Philip, Salman, Mootaz M., Abir-Awan, Mohammed, Al-Jubair, Tamim, Törnroth- Horsefield, Susanna, Conner, Alex C., Bill, Roslyn M.
Publicado 2020

Water channel pore size determines exclusion properties but not solute selectivity

por Kitchen, Philip, Salman, Mootaz M., Pickel, Simone U., Jennings, Jordan, Törnroth-Horsefield, Susanna, Conner, Matthew T., Bill, Roslyn M., Conner, Alex C.
Publicado 2019

Rapid Aquaporin Translocation Regulates Cellular Water Flow: MECHANISM OF HYPOTONICITY-INDUCED SUBCELLULAR LOCALIZATION OF AQUAPORIN 1 WATER CHANNEL

por Conner, Matthew T., Conner, Alex C., Bland, Charlotte E., Taylor, Luke H. J., Brown, James E. P., Parri, H. Rheinallt, Bill, Roslyn M.
Publicado 2012

Structure–activity relationships of the N-terminus of calcitonin gene-related peptide: key roles of alanine-5 and threonine-6 in receptor activation

por Hay, Debbie L, Harris, Paul WR, Kowalczyk, Renata, Brimble, Margaret A, Rathbone, Dan L, Barwell, James, Conner, Alex C, Poyner, David R
Publicado 2014

Emerging roles for dynamic aquaporin-4 subcellular relocalization in CNS water homeostasis

por Salman, Mootaz M, Kitchen, Philip, Halsey, Andrea, Wang, Marie Xun, Törnroth-Horsefield, Susanna, Conner, Alex C, Badaut, Jerome, Iliff, Jeffrey J, Bill, Roslyn M
Publicado 2021

Similarity between class A and class B G-protein-coupled receptors exemplified through calcitonin gene-related peptide receptor modelling and mutagenesis studies

por Vohra, Shabana, Taddese, Bruck, Conner, Alex C., Poyner, David R., Hay, Debbie L., Barwell, James, Reeves, Philip J., Upton, Graham J. G., Reynolds, Christopher A.
Publicado 2013

Receptor activity-modifying protein dependent and independent activation mechanisms in the coupling of calcitonin gene-related peptide and adrenomedullin receptors to Gs

por Woolley, Michael J., Reynolds, Christopher A., Simms, John, Walker, Christopher S., Mobarec, Juan Carlos, Garelja, Michael L., Conner, Alex C., Poyner, David R., Hay, Debbie L.
Publicado 2017

The role of ECL2 in CGRP receptor activation: a combined modelling and experimental approach

por Woolley, Michael. J., Watkins, Harriet A., Taddese, Bruck, Karakullukcu, Z. Gamze, Barwell, James, Smith, Kevin J., Hay, Debbie L., Poyner, David R., Reynolds, Christopher A., Conner, Alex C.
Publicado 2013

Downregulation of aquaporin 3 inhibits cellular proliferation, migration and invasion in the MDA-MB-231 breast cancer cell line

por Arif, Muhammad, Kitchen, Philip, Conner, Matthew T., Hill, Eric J., Nagel, David, Bill, Roslyn M., Dunmore, Simon J., Armesilla, Angel L., Gross, Stephane, Carmichael, Amtul R., Conner, Alex C., Brown, James E.
Publicado 2018

Targeting Aquaporin-4 Subcellular Localization to Treat Central Nervous System Edema

por Kitchen, Philip, Salman, Mootaz M., Halsey, Andrea M., Clarke-Bland, Charlotte, MacDonald, Justin A., Ishida, Hiroaki, Vogel, Hans J., Almutiri, Sharif, Logan, Ann, Kreida, Stefan, Al-Jubair, Tamim, Winkel Missel, Julie, Gourdon, Pontus, Törnroth-Horsefield, Susanna, Conner, Matthew T., Ahmed, Zubair, Conner, Alex C., Bill, Roslyn M.
Publicado 2020

Receptor Activity-modifying Proteins 2 and 3 Generate Adrenomedullin Receptor Subtypes with Distinct Molecular Properties

por Watkins, Harriet A., Chakravarthy, Madhuri, Abhayawardana, Rekhati S., Gingell, Joseph J., Garelja, Michael, Pardamwar, Meenakshi, McElhinney, James M. W. R., Lathbridge, Alex, Constantine, Arran, Harris, Paul W. R., Yuen, Tsz-Ying, Brimble, Margaret A., Barwell, James, Poyner, David R., Woolley, Michael J., Conner, Alex C., Pioszak, Augen A., Reynolds, Christopher A., Hay, Debbie L.
Publicado 2016

THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Ion channels

por Alexander, Stephen PH, Mathie, Alistair, Peters, John A, Veale, Emma L, Striessnig, Jörg, Kelly, Eamonn, Armstrong, Jane F, Faccenda, Elena, Harding, Simon D, Pawson, Adam J, Sharman, Joanna L, Southan, Christopher, Davies, Jamie A, Aldrich, Richard W, Becirovic, Elvir, Biel, Martin, Catterall, William A, Conner, Alex C, Davies, Paul, Delling, Markus, Virgilio, Francesco Di, Falzoni, Simonetta, George, Chandy, Goldstein, Steve AN, Grissmer, Stephan, Ha, Kotdaji, Hammelmann, Verena, Hanukoglu, Israel, Jarvis, Mike, Jensen, Anders A, Kaczmarek, Leonard K, Kellenberger, Stephan, Kennedy, Charles, King, Brian, Lynch, Joseph W, Perez-Reyes, Edward, Plant, Leigh D, Rash, Lachlan D, Ren, Dejian, Sivilotti, Lucia G, Smart, Trevor G, Snutch, Terrance P, Tian, Jinbin, Van den Eynde, Charlotte, Vriens, Joris, Wei, Aguan D, Winn, Brenda T, Wulff, Heike, Xu, Haoxing, Yue, Lixia, Zhang, Xiaoli, Zhu, Michael
Publicado 2019