Glucose dysregulation in pre-clinical Alzheimer’s disease

por Connolly, Niamh M. C., Theurey, Pierre, Pizzo, Paola
Publicado 2019

Targeting the apoptosis pathway to treat tumours of the paediatric nervous system

por Fitzgerald, Marie-Claire, O’Halloran, Philip J., Connolly, Niamh M. C., Murphy, Brona M.
Publicado 2022

Computational Analysis of AMPK-Mediated Neuroprotection Suggests Acute Excitotoxic Bioenergetics and Glucose Dynamics Are Regulated by a Minimal Set of Critical Reactions

por Connolly, Niamh M. C., D’Orsi, Beatrice, Monsefi, Naser, Huber, Heinrich J., Prehn, Jochen H. M.
Publicado 2016

The identification of BCL-XL and MCL-1 as key anti-apoptotic proteins in medulloblastoma that mediate distinct roles in chemotherapy resistance

por Fitzgerald, Marie-Claire, O’Halloran, Philip J., Kerrane, Sean A., Ní Chonghaile, Triona, Connolly, Niamh M. C., Murphy, Brona M.
Publicado 2023

Defining external factors that determine neuronal survival, apoptosis and necrosis during excitotoxic injury using a high content screening imaging platform

por Anilkumar, Ujval, Weisova, Petronela, Schmid, Jasmin, Bernas, Tytus, Huber, Heinrich J., Düssmann, Heiko, Connolly, Niamh M. C., Prehn, Jochen H. M.
Publicado 2017

Altered Biogenesis and MicroRNA Content of Hippocampal Exosomes Following Experimental Status Epilepticus

por Batool, Aasia, Hill, Thomas D. M., Nguyen, Ngoc T., Langa, Elena, Diviney, Mairéad, Mooney, Catherine, Brennan, Gary P., Connolly, Niamh M. C., Sanz-Rodriguez, Amaya, Cavanagh, Brenton L., Henshall, David C.
Publicado 2020

Systems biology identifies preserved integrity but impaired metabolism of mitochondria due to a glycolytic defect in Alzheimer's disease neurons

por Theurey, Pierre, Connolly, Niamh M. C., Fortunati, Ilaria, Basso, Emy, Lauwen, Susette, Ferrante, Camilla, Moreira Pinho, Catarina, Joselin, Alvin, Gioran, Anna, Bano, Daniele, Park, David S., Ankarcrona, Maria, Pizzo, Paola, Prehn, Jochen H. M.
Publicado 2019

GABA Regulation of Burst Firing in Hippocampal Astrocyte Neural Circuit: A Biophysical Model

por Liu, Junxiu, McDaid, Liam, Araque, Alfonso, Wade, John, Harkin, Jim, Karim, Shvan, Henshall, David C., Connolly, Niamh M. C., Johnson, Anju P., Tyrrell, Andy M., Timmis, Jon, Millard, Alan G., Hilder, James, Halliday, David M.
Publicado 2019

Dual-center, dual-platform microRNA profiling identifies potential plasma biomarkers of adult temporal lobe epilepsy

por Raoof, Rana, Bauer, Sebastian, El Naggar, Hany, Connolly, Niamh M.C., Brennan, Gary P., Brindley, Elizabeth, Hill, Thomas, McArdle, Hazel, Spain, Elaine, Forster, Robert J., Prehn, Jochen H.M., Hamer, Hajo, Delanty, Norman, Rosenow, Felix, Mooney, Catherine, Henshall, David C.
Publicado 2018

Cerebrospinal fluid microRNAs are potential biomarkers of temporal lobe epilepsy and status epilepticus

por Raoof, Rana, Jimenez-Mateos, Eva M., Bauer, Sebastian, Tackenberg, Björn, Rosenow, Felix, Lang, Johannes, Onugoren, Müjgan Dogan, Hamer, Hajo, Huchtemann, Tessa, Körtvélyessy, Peter, Connolly, Niamh M. C., Pfeiffer, Shona, Prehn, Jochen H. M., Farrell, Michael A., O’Brien, Donncha F., Henshall, David C., Mooney, Catherine
Publicado 2017

Systemic delivery of antagomirs during blood-brain barrier disruption is disease-modifying in experimental epilepsy

por Reschke, Cristina R., Silva, Luiz F.A., Vangoor, Vamshidhar R., Rosso, Massimo, David, Bastian, Cavanagh, Brenton L., Connolly, Niamh M.C., Brennan, Gary P., Sanz-Rodriguez, Amaya, Mooney, Catherine, Batool, Aasia, Greene, Chris, Brennan, Marian, Conroy, Ronan M., Rüber, Theodor, Prehn, Jochen H.M., Campbell, Matthew, Pasterkamp, R. Jeroen, Henshall, David C.
Publicado 2021

MicroRNA-335-5p suppresses voltage-gated sodium channel expression and may be a target for seizure control

por Heiland, Mona, Connolly, Niamh M. C., Mamad, Omar, Nguyen, Ngoc T., Kesavan, Jaideep C., Langa, Elena, Fanning, Kevin, Sanfeliu, Albert, Yan, Yan, Su, Junyi, Venø, Morten T., Costard, Lara S., Neubert, Valentin, Engel, Tobias, Hill, Thomas D. M., Freiman, Thomas M., Mahesh, Arun, Tiwari, Vijay K., Rosenow, Felix, Bauer, Sebastian, Kjems, Jørgen, Morris, Gareth, Henshall, David C.
Publicado 2023

Neuronal cell-based high-throughput screen for enhancers of mitochondrial function reveals luteolin as a modulator of mitochondria-endoplasmic reticulum coupling

por Naia, Luana, Pinho, Catarina M., Dentoni, Giacomo, Liu, Jianping, Leal, Nuno Santos, Ferreira, Duarte M. S., Schreiner, Bernadette, Filadi, Riccardo, Fão, Lígia, Connolly, Niamh M. C., Forsell, Pontus, Nordvall, Gunnar, Shimozawa, Makoto, Greotti, Elisa, Basso, Emy, Theurey, Pierre, Gioran, Anna, Joselin, Alvin, Arsenian-Henriksson, Marie, Nilsson, Per, Rego, A. Cristina, Ruas, Jorge L., Park, David, Bano, Daniele, Pizzo, Paola, Prehn, Jochen H. M., Ankarcrona, Maria
Publicado 2021

A systems approach delivers a functional microRNA catalog and expanded targets for seizure suppression in temporal lobe epilepsy

por Venø, Morten T., Reschke, Cristina R., Morris, Gareth, Connolly, Niamh M. C., Su, Junyi, Yan, Yan, Engel, Tobias, Jimenez-Mateos, Eva M., Harder, Lea M., Pultz, Dennis, Haunsberger, Stefan J., Pal, Ajay, Heller, Janosch P., Campbell, Aoife, Langa, Elena, Brennan, Gary P., Conboy, Karen, Richardson, Amy, Norwood, Braxton A., Costard, Lara S., Neubert, Valentin, Del Gallo, Federico, Salvetti, Beatrice, Vangoor, Vamshidhar R., Sanz-Rodriguez, Amaya, Muilu, Juha, Fabene, Paolo F., Pasterkamp, R. Jeroen, Prehn, Jochen H. M., Schorge, Stephanie, Andersen, Jens S., Rosenow, Felix, Bauer, Sebastian, Kjems, Jørgen, Henshall, David C.
Publicado 2020

Guidelines on experimental methods to assess mitochondrial dysfunction in cellular models of neurodegenerative diseases

por Connolly, Niamh M. C., Theurey, Pierre, Adam-Vizi, Vera, Bazan, Nicolas G., Bernardi, Paolo, Bolaños, Juan P., Culmsee, Carsten, Dawson, Valina L., Deshmukh, Mohanish, Duchen, Michael R., Düssmann, Heiko, Fiskum, Gary, Galindo, Maria F., Hardingham, Giles E., Hardwick, J. Marie, Jekabsons, Mika B., Jonas, Elizabeth A., Jordán, Joaquin, Lipton, Stuart A., Manfredi, Giovanni, Mattson, Mark P., McLaughlin, BethAnn, Methner, Axel, Murphy, Anne N., Murphy, Michael P., Nicholls, David G., Polster, Brian M., Pozzan, Tullio, Rizzuto, Rosario, Satrústegui, Jorgina, Slack, Ruth S., Swanson, Raymond A., Swerdlow, Russell H., Will, Yvonne, Ying, Zheng, Joselin, Alvin, Gioran, Anna, Moreira Pinho, Catarina, Watters, Orla, Salvucci, Manuela, Llorente-Folch, Irene, Park, David S., Bano, Daniele, Ankarcrona, Maria, Pizzo, Paola, Prehn, Jochen H. M.
Publicado 2017