Automated microscopy for high-content RNAi screening

por Conrad, Christian, Gerlich, Daniel W.
Publicado 2010

Unraveling mitotic protein networks by 3D multiplexed epitope drug screening

por Maier, Lorenz J, Kallenberger, Stefan M, Jechow, Katharina, Waschow, Marcel, Eils, Roland, Conrad, Christian
Publicado 2018

resVAE ensemble: Unsupervised identification of gene sets in multi-modal single-cell sequencing data using deep ensembles

por Ten, Foo Wei, Yuan, Dongsheng, Jabareen, Nabil, Phua, Yin Jun, Eils, Roland, Lukassen, Sören, Conrad, Christian
Publicado 2023

Automated 3D light-sheet screening with high spatiotemporal resolution reveals mitotic phenotypes

por Eismann, Björn, Krieger, Teresa G., Beneke, Jürgen, Bulkescher, Ruben, Adam, Lukas, Erfle, Holger, Herrmann, Carl, Eils, Roland, Conrad, Christian
Publicado 2020

Modeling glioblastoma invasion using human brain organoids and single-cell transcriptomics

por Krieger, Teresa G, Tirier, Stephan M, Park, Jeongbin, Jechow, Katharina, Eisemann, Tanja, Peterziel, Heike, Angel, Peter, Eils, Roland, Conrad, Christian
Publicado 2020

Intratumoral Heterogeneity and Immune Modulation in Lung Adenocarcinoma in Female Smokers and Never Smokers

por Trefzer, Timo B., Schneider, Marc A., Jechow, Katharina, Chua, Robert Lorenz, Muley, Thomas, Winter, Hauke, Kriegsmann, Mark, Meister, Michael, Eils, Roland, Conrad, Christian
Publicado 2022

Patient-specific modeling of stroma-mediated chemoresistance of pancreatic cancer using a three-dimensional organoid-fibroblast co-culture system

por Schuth, Sebastian, Le Blanc, Solange, Krieger, Teresa G., Jabs, Julia, Schenk, Miriam, Giese, Nathalia A., Büchler, Markus W., Eils, Roland, Conrad, Christian, Strobel, Oliver
Publicado 2022

Single-cell analysis of patient-derived PDAC organoids reveals cell state heterogeneity and a conserved developmental hierarchy

por Krieger, Teresa G., Le Blanc, Solange, Jabs, Julia, Ten, Foo Wei, Ishaque, Naveed, Jechow, Katharina, Debnath, Olivia, Leonhardt, Carl-Stephan, Giri, Anamika, Eils, Roland, Strobel, Oliver, Conrad, Christian
Publicado 2021

SARS‐CoV‐2 receptor ACE2 and TMPRSS2 are primarily expressed in bronchial transient secretory cells

por Lukassen, Soeren, Chua, Robert Lorenz, Trefzer, Timo, Kahn, Nicolas C, Schneider, Marc A, Muley, Thomas, Winter, Hauke, Meister, Michael, Veith, Carmen, Boots, Agnes W, Hennig, Bianca P, Kreuter, Michael, Conrad, Christian, Eils, Roland
Publicado 2020

Convergent origination of a Drosophila-like dosage compensation mechanism in a reptile lineage

por Marin, Ray, Cortez, Diego, Lamanna, Francesco, Pradeepa, Madapura M., Leushkin, Evgeny, Julien, Philippe, Liechti, Angélica, Halbert, Jean, Brüning, Thoomke, Mössinger, Katharina, Trefzer, Timo, Conrad, Christian, Kerver, Halie N., Wade, Juli, Tschopp, Patrick, Kaessmann, Henrik
Publicado 2017

Screening drug effects in patient‐derived cancer cells links organoid responses to genome alterations

por Jabs, Julia, Zickgraf, Franziska M, Park, Jeongbin, Wagner, Steve, Jiang, Xiaoqi, Jechow, Katharina, Kleinheinz, Kortine, Toprak, Umut H, Schneider, Marc A, Meister, Michael, Spaich, Saskia, Sütterlin, Marc, Schlesner, Matthias, Trumpp, Andreas, Sprick, Martin, Eils, Roland, Conrad, Christian
Publicado 2017

Pheno-seq – linking visual features and gene expression in 3D cell culture systems

por Tirier, Stephan M., Park, Jeongbin, Preußer, Friedrich, Amrhein, Lisa, Gu, Zuguang, Steiger, Simon, Mallm, Jan-Philipp, Krieger, Teresa, Waschow, Marcel, Eismann, Björn, Gut, Marta, Gut, Ivo G., Rippe, Karsten, Schlesner, Matthias, Theis, Fabian, Fuchs, Christiane, Ball, Claudia R., Glimm, Hanno, Eils, Roland, Conrad, Christian
Publicado 2019

ELF5 is a potential respiratory epithelial cell-specific risk gene for severe COVID-19

por Pietzner, Maik, Chua, Robert Lorenz, Wheeler, Eleanor, Jechow, Katharina, Willett, Julian D. S., Radbruch, Helena, Trump, Saskia, Heidecker, Bettina, Zeberg, Hugo, Heppner, Frank L., Eils, Roland, Mall, Marcus A., Richards, J. Brent, Sander, Leif-Erik, Lehmann, Irina, Lukassen, Sören, Wareham, Nicholas J., Conrad, Christian, Langenberg, Claudia
Publicado 2022

Integrated halide perovskite photoelectrochemical cells with solar-driven water-splitting efficiency of 20.8%

por Fehr, Austin M. K., Agrawal, Ayush, Mandani, Faiz, Conrad, Christian L., Jiang, Qi, Park, So Yeon, Alley, Olivia, Li, Bor, Sidhik, Siraj, Metcalf, Isaac, Botello, Christopher, Young, James L., Even, Jacky, Blancon, Jean Christophe, Deutsch, Todd G., Zhu, Kai, Albrecht, Steve, Toma, Francesca M., Wong, Michael, Mohite, Aditya D.
Publicado 2023

Functional States in Tumor-Initiating Cell Differentiation in Human Colorectal Cancer

por Zowada, Martina K., Tirier, Stephan M., Dieter, Sebastian M., Krieger, Teresa G., Oberlack, Ava, Chua, Robert Lorenz, Huerta, Mario, Ten, Foo Wei, Laaber, Karin, Park, Jeongbin, Jechow, Katharina, Müller, Torsten, Kalxdorf, Mathias, Kriegsmann, Mark, Kriegsmann, Katharina, Herbst, Friederike, Krijgsveld, Jeroen, Schneider, Martin, Eils, Roland, Glimm, Hanno, Conrad, Christian, Ball, Claudia R.
Publicado 2021

The molecular evolution of spermatogenesis across mammals

por Murat, Florent, Mbengue, Noe, Winge, Sofia Boeg, Trefzer, Timo, Leushkin, Evgeny, Sepp, Mari, Cardoso-Moreira, Margarida, Schmidt, Julia, Schneider, Celine, Mößinger, Katharina, Brüning, Thoomke, Lamanna, Francesco, Belles, Meritxell Riera, Conrad, Christian, Kondova, Ivanela, Bontrop, Ronald, Behr, Rüdiger, Khaitovich, Philipp, Pääbo, Svante, Marques-Bonet, Tomas, Grützner, Frank, Almstrup, Kristian, Schierup, Mikkel Heide, Kaessmann, Henrik
Publicado 2022

90K/LGALS3BP expression is upregulated in COVID-19 but may not restrict SARS-CoV-2 infection

por Bosquillon de Jarcy, Laure, Akbil, Bengisu, Mhlekude, Baxolele, Leyens, Johanna, Postmus, Dylan, Harnisch, Greta, Jansen, Jenny, Schmidt, Marie L., Aigner, Annette, Pott, Fabian, Chua, Robert Lorenz, Krist, Lilian, Gentile, Roberta, Mühlemann, Barbara, Jones, Terence C., Niemeyer, Daniela, Fricke, Julia, Keil, Thomas, Pischon, Tobias, Janke, Jürgen, Conrad, Christian, Iacobelli, Stefano, Drosten, Christian, Corman, Victor M., Ralser, Markus, Eils, Roland, Kurth, Florian, Sander, Leif, Goffinet, Christine
Publicado 2023

SARS-CoV-2-mediated dysregulation of metabolism and autophagy uncovers host-targeting antivirals

por Gassen, Nils C., Papies, Jan, Bajaj, Thomas, Emanuel, Jackson, Dethloff, Frederik, Chua, Robert Lorenz, Trimpert, Jakob, Heinemann, Nicolas, Niemeyer, Christine, Weege, Friderike, Hönzke, Katja, Aschman, Tom, Heinz, Daniel E., Weckmann, Katja, Ebert, Tim, Zellner, Andreas, Lennarz, Martina, Wyler, Emanuel, Schroeder, Simon, Richter, Anja, Niemeyer, Daniela, Hoffmann, Karen, Meyer, Thomas F., Heppner, Frank L., Corman, Victor M., Landthaler, Markus, Hocke, Andreas C., Morkel, Markus, Osterrieder, Nikolaus, Conrad, Christian, Eils, Roland, Radbruch, Helena, Giavalisco, Patrick, Drosten, Christian, Müller, Marcel A.
Publicado 2021

SARS-CoV-2 infection triggers profibrotic macrophage responses and lung fibrosis

por Wendisch, Daniel, Dietrich, Oliver, Mari, Tommaso, von Stillfried, Saskia, Ibarra, Ignacio L., Mittermaier, Mirja, Mache, Christin, Chua, Robert Lorenz, Knoll, Rainer, Timm, Sara, Brumhard, Sophia, Krammer, Tobias, Zauber, Henrik, Hiller, Anna Luisa, Pascual-Reguant, Anna, Mothes, Ronja, Bülow, Roman David, Schulze, Jessica, Leipold, Alexander M., Djudjaj, Sonja, Erhard, Florian, Geffers, Robert, Pott, Fabian, Kazmierski, Julia, Radke, Josefine, Pergantis, Panagiotis, Baßler, Kevin, Conrad, Claudia, Aschenbrenner, Anna C., Sawitzki, Birgit, Landthaler, Markus, Wyler, Emanuel, Horst, David, Hippenstiel, Stefan, Hocke, Andreas, Heppner, Frank L., Uhrig, Alexander, Garcia, Carmen, Machleidt, Felix, Herold, Susanne, Elezkurtaj, Sefer, Thibeault, Charlotte, Witzenrath, Martin, Cochain, Clément, Suttorp, Norbert, Drosten, Christian, Goffinet, Christine, Kurth, Florian, Schultze, Joachim L., Radbruch, Helena, Ochs, Matthias, Eils, Roland, Müller-Redetzky, Holger, Hauser, Anja E., Luecken, Malte D., Theis, Fabian J., Conrad, Christian, Wolff, Thorsten, Boor, Peter, Selbach, Matthias, Saliba, Antoine-Emmanuel, Sander, Leif Erik
Publicado 2021