Targeting T Cell Immunometabolism for Cancer Immunotherapy; Understanding the Impact of the Tumor Microenvironment

por Mockler, Mary B., Conroy, Melissa J., Lysaght, Joanne
Publicado 2014

Harnessing Natural Killer Cells in Non-Small Cell Lung Cancer

por Russell, Éilis, Conroy, Melissa J., Barr, Martin P.
Publicado 2022

Examination and characterisation of the effect of amitriptyline therapy for chronic neuropathic pain on neuropeptide and proteomic constituents of human cerebrospinal fluid

por Royds, Jonathan, Cassidy, Hilary, Conroy, Melissa J., Dunne, Margaret R., Lysaght, Joanne, McCrory, Connail
Publicado 2020

The Omentum in Obesity-Associated Cancer: A Hindrance to Effective Natural Killer Cell Migration towards Tumour Which Can Be Overcome by CX3CR1 Antagonism

por Mylod, Eimear, O’Connell, Fiona, Donlon, Noel E., Butler, Christine, Reynolds, John V., Lysaght, Joanne, Conroy, Melissa J.
Publicado 2021

Identifying a Novel Role for Fractalkine (CX3CL1) in Memory CD8(+) T Cell Accumulation in the Omentum of Obesity-Associated Cancer Patients

por Conroy, Melissa J., Maher, Stephen G., Melo, Ashanty M., Doyle, Suzanne L., Foley, Emma, Reynolds, John V., Long, Aideen, Lysaght, Joanne
Publicado 2018

Investigating the Effects of Olaparib on the Susceptibility of Glioblastoma Multiforme Tumour Cells to Natural Killer Cell-Mediated Responses

por Moran, Jennifer, Mylod, Eimear, Kane, Laura E., Marion, Caroline, Keenan, Emily, Mekhaeil, Marianna, Lysaght, Joanne, Dev, Kumlesh K., O’Sullivan, Jacintha, Conroy, Melissa J.
Publicado 2023

Investigating the susceptibility of treatment-resistant oesophageal tumours to natural killer cell-mediated responses

por Mylod, Eimear, McKenna, Ellen, Davern, Maria, Barr, Martin P., Donlon, Noel E., Bibby, Becky A. S., Bhardwaj, Anshul, Reynolds, John V., Lysaght, Joanne, Maher, Stephen G., Conroy, Melissa J.
Publicado 2022

Visceral Adipose Tissue Modulates Radiosensitivity in Oesophageal Adenocarcinoma

por Mongan, Ann Marie, Lynam-Lennon, Niamh, Doyle, Suzanne L, Casey, Rory, Carr, Eibhlin, Cannon, Aoife, Conroy, Melissa J, Pidgeon, Graham P, Brennan, Lorraine, Lysaght, Joanne, Reynolds, John V., O'Sullivan, Jacintha
Publicado 2019

Cooperation between chemotherapy and immune checkpoint blockade to enhance anti-tumour T cell immunity in oesophageal adenocarcinoma

por Davern, Maria, Donlon, Noel E., O’ Connell, Fiona, Sheppard, Andrew D., Hayes, Conall, King, Ross, Temperley, Hugo, Butler, Christine, Bhardwaj, Anshul, Moore, Jenny, Bracken-Clarke, Dara, Donohoe, Claire, Ravi, Narayanasamy, Reynolds, John V., Maher, Stephen G., Conroy, Melissa J., Lysaght, Joanne
Publicado 2022

Acidosis significantly alters immune checkpoint expression profiles of T cells from oesophageal adenocarcinoma patients

por Davern, Maria, Donlon, Noel E., O’Connell, Fiona, Gaughan, Caoimhe, O’Donovan, Cillian, Habash, Mohammed, Sheppard, Andrew D., MacLean, Michael, Dunne, Margaret R., Moore, Jenny, Temperley, Hugo, Conroy, Melissa J., Butler, Christine, Bhardwaj, Anshul, Ravi, Narayanasamy, Donohoe, Claire L., Reynolds, John V., Lysaght, Joanne
Publicado 2022

Nutrient deprivation and hypoxia alter T cell immune checkpoint expression: potential impact for immunotherapy

por Davern, Maria, Donlon, Noel E., O’Connell, Fiona, Gaughan, Caoimhe, O’Donovan, Cillian, McGrath, Jason, Sheppard, Andrew D., Hayes, Conall, King, Ross, Temperley, Hugo, MacLean, Michael, Bulter, Christine, Bhardwaj, Anshul, Moore, Jenny, Donohoe, Claire, Ravi, Narayanasamy, Conroy, Melissa J., Reynolds, John V., Lysaght, Joanne
Publicado 2022

The Impact of Esophageal Oncological Surgery on Perioperative Immune Function; Implications for Adjuvant Immune Checkpoint Inhibition

por Donlon, Noel E., Davern, Maria, Sheppard, Andrew D., O’Connell, Fiona, Dunne, Margaret R., Hayes, Conall, Mylod, Eimear, Ramjit, Sinead, Temperley, Hugo, Mac Lean, Michael, Cotter, Gillian, Bhardwaj, Anshul, Butler, Christine, Conroy, Melissa J., O’Sullivan, Jacintha, Ravi, Narayanasamy, Donohoe, Claire L., Reynolds, John V., Lysaght, Joanne
Publicado 2022

FLOT and CROSS chemotherapy regimens alter the frequency of CD27(+) and CD69(+) T cells in oesophagogastric adenocarcinomas: implications for combination with immunotherapy

por Davern, Maria, Donlon, Noel E., Sheppard, Andrew S., Majcher, Klaudia D., Connell, Fiona O’, Heeran, Aisling B., Grant, Malika, Farrell, Robert A., Hayes, Conall, Bracken-Clarke, Dara, Conroy, Melissa J., Foley, Emma, Toole, Dermot O’, Bhardwaj, Anshul, Ravi, Narayanasamy, Reynolds, John V., Maher, Stephen G., Sullivan, Jacintha O’, Lysaght, Joanne
Publicado 2022

Visceral adipose tissue secretome from early and late-stage oesophageal cancer patients differentially affects effector and regulatory T cells

por Davern, Maria, Bracken-Clarke, Dara, Donlon, Noel E., Sheppard, Andrew D., Connell, Fiona O’, Heeran, Aisling B., Majcher, Klaudia, Conroy, Melissa J., Mylod, Eimear, Butler, Christine, Donohoe, Claire, Donnell, Dearbhaile O’, Lowery, Maeve, Bhardwaj, Anshul, Ravi, Narayanasamy, Melo, Ashanty A., Sullivan, Jacintha O’, Reynolds, John V., Lysaght, Joanne
Publicado 2023

Mucosal-Associated Invariant T Cells Display Diminished Effector Capacity in Oesophageal Adenocarcinoma

por Melo, Ashanty M., O'Brien, Aisling M., Phelan, James J., Kennedy, Susan A., Wood, Nicole A. W., Veerapen, Natacha, Besra, Gurdyal S., Clarke, Niamh E., Foley, Emma K., Ravi, Akshaya, MacCarthy, Finbar, O'Toole, Dermot, Ravi, Narayamasami, Reynolds, John V., Conroy, Melissa J., Hogan, Andrew E., O'Sullivan, Jacintha, Dunne, Margaret R.
Publicado 2019