Marine-Derived Secondary Metabolites as Promising Epigenetic Bio-Compounds for Anticancer Therapy

por Conte, Mariarosaria, Fontana, Elisabetta, Nebbioso, Angela, Altucci, Lucia
Publicado 2020

Recent Advancement in Anticancer Compounds from Marine Organisms: Approval, Use and Bioinformatic Approaches to Predict New Targets

por Santaniello, Giovanna, Nebbioso, Angela, Altucci, Lucia, Conte, Mariarosaria
Publicado 2022

HDAC2‐dependent miRNA signature in acute myeloid leukemia

por Conte, Mariarosaria, Dell'Aversana, Carmela, Sgueglia, Giulia, Carissimo, Annamaria, Altucci, Lucia
Publicado 2019

Editorial: Chemical Innovative Approaches in Cancer Molecular Medicine and Translational Clinical Research

por Benedetti, Rosaria, Conte, Mariarosaria, Dell'Aversana, Carmela, Hansen, Finn K., Zwergel, Clemens
Publicado 2020

Forskolin Sensitizes Human Acute Myeloid Leukemia Cells to H3K27me2/3 Demethylases GSKJ4 Inhibitor via Protein Kinase A

por Illiano, Michela, Conte, Mariarosaria, Sapio, Luigi, Nebbioso, Angela, Spina, Annamaria, Altucci, Lucia, Naviglio, Silvio
Publicado 2018

Targeting HDAC2-Mediated Immune Regulation to Overcome Therapeutic Resistance in Mutant Colorectal Cancer

por Conte, Mariarosaria, Di Mauro, Annabella, Capasso, Lucia, Montella, Liliana, De Simone, Mariacarla, Nebbioso, Angela, Altucci, Lucia
Publicado 2023

Relevance of AIF/CypA Lethal Pathway in SH-SY5Y Cells Treated with Staurosporine

por Conte, Mariarosaria, Palumbo, Rosanna, Monti, Alessandra, Fontana, Elisabetta, Nebbioso, Angela, Ruvo, Menotti, Altucci, Lucia, Doti, Nunzianna
Publicado 2021

Bisphenol A induces cell cycle arrest in primary and prostate cancer cells through EGFR/ERK/p53 signaling pathway activation

por Bilancio, Antonio, Bontempo, Paola, Di Donato, Marzia, Conte, Mariarosaria, Giovannelli, Pia, Altucci, Lucia, Migliaccio, Antimo, Castoria, Gabriella
Publicado 2017

The KDM Inhibitor GSKJ4 Triggers CREB Downregulation via a Protein Kinase A and Proteasome-Dependent Mechanism in Human Acute Myeloid Leukemia Cells

por Illiano, Michela, Conte, Mariarosaria, Salzillo, Alessia, Ragone, Angela, Spina, Annamaria, Nebbioso, Angela, Altucci, Lucia, Sapio, Luigi, Naviglio, Silvio
Publicado 2020

Cytotoxic Potential of the Marine Diatom Thalassiosira rotula: Insights into Bioactivity of 24-Methylene Cholesterol

por Cutignano, Adele, Conte, Mariarosaria, Tirino, Virginia, Del Vecchio, Vitale, De Angelis, Roberto, Nebbioso, Angela, Altucci, Lucia, Romano, Giovanna
Publicado 2022

SIRT1 activation promotes energy homeostasis and reprograms liver cancer metabolism

por Varghese, Benluvankar, Chianese, Ugo, Capasso, Lucia, Sian, Veronica, Bontempo, Paola, Conte, Mariarosaria, Benedetti, Rosaria, Altucci, Lucia, Carafa, Vincenzo, Nebbioso, Angela
Publicado 2023

Sarcoma Common MHC-I Haplotype Restricts Tumor-Specific CD8+ T Cell Response

por Mosca, Laura, de Angelis, Alessandra, Ronchi, Andrea, De Chiara, Annarosaria, Fazioli, Flavio, Ruosi, Carlo, Altucci, Lucia, Conte, Mariarosaria, de Nigris, Filomena
Publicado 2022

HDAC2 deregulation in tumorigenesis is causally connected to repression of immune modulation and defense escape

por Conte, Mariarosaria, Dell'Aversana, Carmela, Benedetti, Rosaria, Petraglia, Francesca, Carissimo, Annamaria, Petrizzi, Valeria Belsito, D'Arco, Alfonso Maria, Abbondanza, Ciro, Nebbioso, Angela, Altucci, Lucia
Publicado 2014

Properly Substituted Cyclic Bis-(2-bromobenzylidene) Compounds Behaved as Dual p300/CARM1 Inhibitors and Induced Apoptosis in Cancer Cells

por Fioravanti, Rossella, Tomassi, Stefano, Di Bello, Elisabetta, Romanelli, Annalisa, Plateroti, Andrea Maria, Benedetti, Rosaria, Conte, Mariarosaria, Novellino, Ettore, Altucci, Lucia, Valente, Sergio, Mai, Antonello
Publicado 2020

Selective class II HDAC inhibitors impair myogenesis by modulating the stability and activity of HDAC–MEF2 complexes

por Nebbioso, Angela, Manzo, Fabio, Miceli, Marco, Conte, Mariarosaria, Manente, Lucrezia, Baldi, Alfonso, De Luca, Antonio, Rotili, Dante, Valente, Sergio, Mai, Antonello, Usiello, Alessandro, Gronemeyer, Hinrich, Altucci, Lucia
Publicado 2009

Monoacylglycerides from the Diatom Skeletonema marinoi Induce Selective Cell Death in Cancer Cells

por Miceli, Marco, Cutignano, Adele, Conte, Mariarosaria, Ummarino, Raffaella, Romanelli, Alessandra, Ruvo, Menotti, Leone, Marilisa, Mercurio, Flavia Anna, Doti, Nunzianna, Manzo, Emiliano, Romano, Giovanna, Altucci, Lucia, Ianora, Adrianna
Publicado 2019

The SGLT-2 inhibitor empagliflozin improves myocardial strain, reduces cardiac fibrosis and pro-inflammatory cytokines in non-diabetic mice treated with doxorubicin

por Quagliariello, Vincenzo, De Laurentiis, Michelino, Rea, Domenica, Barbieri, Antonio, Monti, Maria Gaia, Carbone, Andreina, Paccone, Andrea, Altucci, Lucia, Conte, Mariarosaria, Canale, Maria Laura, Botti, Gerardo, Maurea, Nicola
Publicado 2021

HDAC Inhibitors Repress BARD1 Isoform Expression in Acute Myeloid Leukemia Cells via Activation of miR-19a and/or b

por Lepore, Ilaria, Dell’Aversana, Carmela, Pilyugin, Maxim, Conte, Mariarosaria, Nebbioso, Angela, De Bellis, Floriana, Tambaro, Francesco P., Izzo, Tiziana, Garcia-Manero, Guillermo, Ferrara, Felicetto, Irminger-Finger, Irmgard, Altucci, Lucia
Publicado 2013

Time-resolved analysis of DNA-protein interactions in living cells by UV laser pulses

por Nebbioso, Angela, Benedetti, Rosaria, Conte, Mariarosaria, Carafa, Vincenzo, De Bellis, Floriana, Shaik, Jani, Matarese, Filomena, Della Ventura, Bartolomeo, Gesuele, Felice, Velotta, Raffaele, Martens, Joost H. A., Stunnenberg, Hendrik G., Altucci, Carlo, Altucci, Lucia
Publicado 2017

HDAC class I inhibitor domatinostat sensitizes pancreatic cancer to chemotherapy by targeting cancer stem cell compartment via FOXM1 modulation

por Roca, Maria Serena, Moccia, Tania, Iannelli, Federica, Testa, Cristina, Vitagliano, Carlo, Minopoli, Michele, Camerlingo, Rosa, De Riso, Giulia, De Cecio, Rossella, Bruzzese, Francesca, Conte, Mariarosaria, Altucci, Lucia, Di Gennaro, Elena, Avallone, Antonio, Leone, Alessandra, Budillon, Alfredo
Publicado 2022