BCG-Mediated Protection against Mycobacterium ulcerans Infection in the Mouse

por Converse, Paul J., Almeida, Deepak V., Nuermberger, Eric L., Grosset, Jacques H.
Publicado 2011

Rapid, Serial, Non-invasive Assessment of Drug Efficacy in Mice with Autoluminescent Mycobacterium ulcerans Infection

por Zhang, Tianyu, Li, Si-Yang, Converse, Paul J., Grosset, Jacques H., Nuermberger, Eric L.
Publicado 2013

Comparative Efficacy of the Novel Diarylquinoline TBAJ-587 and Bedaquiline against a Resistant Rv0678 Mutant in a Mouse Model of Tuberculosis

por Xu, Jian, Converse, Paul J., Upton, Anna M., Mdluli, Khisimuzi, Fotouhi, Nader, Nuermberger, Eric L.
Publicado 2021

Activities of Rifampin, Rifapentine and Clarithromycin Alone and in Combination against Mycobacterium ulcerans Disease in Mice

por Almeida, Deepak, Converse, Paul J., Ahmad, Zahoor, Dooley, Kelly E., Nuermberger, Eric L., Grosset, Jacques H.
Publicado 2011

Comparative Efficacy of the Novel Diarylquinoline TBAJ-876 and Bedaquiline against a Resistant Rv0678 Mutant in a Mouse Model of Tuberculosis

por Almeida, Deepak, Converse, Paul J., Li, Si-Yang, Upton, Anna M., Fotouhi, Nader, Nuermberger, Eric L.
Publicado 2021

Bactericidal Activity Does Not Predict Sterilizing Activity: The Case of Rifapentine in the Murine Model of Mycobacterium ulcerans Disease

por Almeida, Deepak V., Converse, Paul J., Li, Si-Yang, Tyagi, Sandeep, Nuermberger, Eric L., Grosset, Jacques H.
Publicado 2013

Bactericidal and Sterilizing Activity of a Novel Regimen with Bedaquiline, Pretomanid, Moxifloxacin, and Pyrazinamide in a Murine Model of Tuberculosis

por Li, Si-Yang, Tasneen, Rokeya, Tyagi, Sandeep, Soni, Heena, Converse, Paul J., Mdluli, Khisimuzi, Nuermberger, Eric L.
Publicado 2017

Dual mTORC1/mTORC2 Inhibition as a Host-Directed Therapeutic Target in Pathologically Distinct Mouse Models of Tuberculosis

por Tasneen, Rokeya, Mortensen, Deborah S., Converse, Paul J., Urbanowski, Michael E., Upton, Anna, Fotouhi, Nader, Nuermberger, Eric, Hawryluk, Natalie
Publicado 2021

Next-Generation Diarylquinolines Improve Sterilizing Activity of Regimens with Pretomanid and the Novel Oxazolidinone TBI-223 in a Mouse Tuberculosis Model

por Li, Si-Yang, Converse, Paul J., Betoudji, Fabrice, Lee, Jin, Mdluli, Khisimuzi, Upton, Anna, Fotouhi, Nader, Nuermberger, Eric L.
Publicado 2023

Microbiological, Histological, Immunological, and Toxin Response to Antibiotic Treatment in the Mouse Model of Mycobacterium ulcerans Disease

por Sarfo, Fred Stephen, Converse, Paul J., Almeida, Deepak V., Zhang, Jihui, Robinson, Clive, Wansbrough-Jones, Mark, Grosset, Jacques H.
Publicado 2013

Altered cellular infiltration and cytokine levels during early Mycobacterium tuberculosis sigC mutant infection are associated with late-stage disease attenuation and milder immuno...

por Abdul-Majid, Khairul-Bariah, Ly, Lan H, Converse, Paul J, Geiman, Deborah E, McMurray, David N, Bishai, William R
Publicado 2008

Efficacy of Rifampin Plus Clofazimine in a Murine Model of Mycobacterium ulcerans Disease

por Converse, Paul J., Tyagi, Sandeep, Xing, Yalan, Li, Si-Yang, Kishi, Yoshito, Adamson, John, Nuermberger, Eric L., Grosset, Jacques H.
Publicado 2015

Accelerated Detection of Mycolactone Production and Response to Antibiotic Treatment in a Mouse Model of Mycobacterium ulcerans Disease

por Converse, Paul J., Xing, Yalan, Kim, Ki Hyun, Tyagi, Sandeep, Li, Si-Yang, Almeida, Deepak V., Nuermberger, Eric L., Grosset, Jacques H., Kishi, Yoshito
Publicado 2014

Mouse model of pulmonary cavitary tuberculosis and expression of matrix metalloproteinase-9

por Ordonez, Alvaro A., Tasneen, Rokeya, Pokkali, Supriya, Xu, Ziyue, Converse, Paul J., Klunk, Mariah H., Mollura, Daniel J., Nuermberger, Eric L., Jain, Sanjay K.
Publicado 2016

Contribution of Pretomanid to Novel Regimens Containing Bedaquiline with either Linezolid or Moxifloxacin and Pyrazinamide in Murine Models of Tuberculosis

por Xu, Jian, Li, Si-Yang, Almeida, Deepak V., Tasneen, Rokeya, Barnes-Boyle, Kala, Converse, Paul J., Upton, Anna M., Mdluli, Khisimuzi, Fotouhi, Nader, Nuermberger, Eric L.
Publicado 2019

Understanding the Significance of Biochemistry in the Storage, Handling, Purification, and Sampling of Amphiphilic Mycolactone

por Kubicek-Sutherland, Jessica Z., Vu, Dung M., Anderson, Aaron S., Sanchez, Timothy C., Converse, Paul J., Martí-Arbona, Ricardo, Nuermberger, Eric L., Swanson, Basil I., Mukundan, Harshini
Publicado 2019

Studies of a Ring-Cleaving Dioxygenase Illuminate the Role of Cholesterol Metabolism in the Pathogenesis of Mycobacterium tuberculosis

por Yam, Katherine C., D'Angelo, Igor, Kalscheuer, Rainer, Zhu, Haizhong, Wang, Jian-Xin, Snieckus, Victor, Ly, Lan H., Converse, Paul J., Jacobs, William R., Strynadka, Natalie, Eltis, Lindsay D.
Publicado 2009

Shorter-course treatment for Mycobacterium ulcerans disease with high-dose rifamycins and clofazimine in a mouse model of Buruli ulcer

por Converse, Paul J., Almeida, Deepak V., Tasneen, Rokeya, Saini, Vikram, Tyagi, Sandeep, Ammerman, Nicole C., Li, Si-Yang, Anders, Nicole M., Rudek, Michelle A., Grosset, Jacques H., Nuermberger, Eric L.
Publicado 2018

Advancing the Therapeutic Potential of Indoleamides for Tuberculosis

por Lun, Shichun, Tasneen, Rokeya, Chaira, Tridib, Stec, Jozef, Onajole, Oluseye K., Yang, Tian J., Cooper, Christopher B., Mdluli, Khisi, Converse, Paul J., Nuermberger, Eric L., Raj, V. Samuel, Kozikowski, Alan, Bishai, William R.
Publicado 2019

A multi-antigenic MVA vaccine increases efficacy of combination chemotherapy against Mycobacterium tuberculosis

por Leung-Theung-Long, Stéphane, Coupet, Charles-Antoine, Gouanvic, Marie, Schmitt, Doris, Ray, Aurélie, Hoffmann, Chantal, Schultz, Huguette, Tyagi, Sandeep, Soni, Heena, Converse, Paul J., Arias, Lilibeth, Kleinpeter, Patricia, Sansas, Benoît, Mdluli, Khisimuzi, Vilaplana, Cristina, Cardona, Pere-Joan, Nuermberger, Eric, Marchand, Jean-Baptiste, Silvestre, Nathalie, Inchauspé, Geneviève
Publicado 2018