IGFBP2 secretion by mammary adipocytes limits breast cancer invasion

por Conway, James R. W., Dinç, Defne D., Follain, Gautier, Paavolainen, Oona, Kaivola, Jasmin, Boström, Pia, Hartiala, Pauliina, Peuhu, Emilia, Ivaska, Johanna
Publicado 2023

A feed-forward loop between SorLA and HER3 determines heregulin response and neratinib resistance

por Al-Akhrass, Hussein, Conway, James R. W., Poulsen, Annemarie Svane Aavild, Paatero, Ilkka, Kaivola, Jasmin, Padzik, Artur, Andersen, Olav M., Ivaska, Johanna
Publicado 2021

Defined extracellular matrix compositions support stiffness-insensitive cell spreading and adhesion signaling

por Conway, James R. W., Isomursu, Aleksi, Follain, Gautier, Härmä, Ville, Jou-Ollé, Eva, Pasquier, Nicolas, Välimäki, Eetu P. O., Rantala, Juha K., Ivaska, Johanna
Publicado 2023

MASTL promotes cell contractility and motility through kinase-independent signaling

por Taskinen, Maria Emilia, Närvä, Elisa, Conway, James R.W., Hinojosa, Laura Soto, Lilla, Sergio, Mai, Anja, De Franceschi, Nicola, Elo, Laura L., Grosse, Robert, Zanivan, Sara, Norman, Jim C., Ivaska, Johanna
Publicado 2020

Three-dimensional organotypic matrices from alternative collagen sources as pre-clinical models for cell biology

por Conway, James R. W., Vennin, Claire, Cazet, Aurélie S., Herrmann, David, Murphy, Kendelle J., Warren, Sean C., Wullkopf, Lena, Boulghourjian, Alice, Zaratzian, Anaiis, Da Silva, Andrew M., Pajic, Marina, Morton, Jennifer P., Cox, Thomas R., Timpson, Paul
Publicado 2017

MASTL overexpression promotes chromosome instability and metastasis in breast cancer

por Rogers, Samuel, McCloy, Rachael A., Parker, Benjamin L., Gallego-Ortega, David, Law, Andrew M. K., Chin, Venessa T., Conway, James R. W., Fey, Dirk, Millar, Ewan K. A., O’Toole, Sandra, Deng, Niantao, Swarbrick, Alexander, Chastain, Paul D., Cesare, Anthony J., Timpson, Paul, Caldon, C. Elizabeth, Croucher, David R., James, David E., Watkins, D. Neil, Burgess, Andrew
Publicado 2018

Intravital Imaging to Monitor Therapeutic Response in Moving Hypoxic Regions Resistant to PI3K Pathway Targeting in Pancreatic Cancer

por Conway, James R.W., Warren, Sean C., Herrmann, David, Murphy, Kendelle J., Cazet, Aurélie S., Vennin, Claire, Shearer, Robert F., Killen, Monica J., Magenau, Astrid, Mélénec, Pauline, Pinese, Mark, Nobis, Max, Zaratzian, Anaiis, Boulghourjian, Alice, Da Silva, Andrew M., del Monte-Nieto, Gonzalo, Adam, Arne S.A., Harvey, Richard P., Haigh, Jody J., Wang, Yingxiao, Croucher, David R., Sansom, Owen J., Pajic, Marina, Caldon, C. Elizabeth, Morton, Jennifer P., Timpson, Paul
Publicado 2018

ELF5 Drives Lung Metastasis in Luminal Breast Cancer through Recruitment of Gr1+ CD11b+ Myeloid-Derived Suppressor Cells

por Gallego-Ortega, David, Ledger, Anita, Roden, Daniel L., Law, Andrew M. K., Magenau, Astrid, Kikhtyak, Zoya, Cho, Christina, Allerdice, Stephanie L., Lee, Heather J., Valdes-Mora, Fatima, Herrmann, David, Salomon, Robert, Young, Adelaide I. J., Lee, Brian Y., Sergio, C. Marcelo, Kaplan, Warren, Piggin, Catherine, Conway, James R. W., Rabinovich, Brian, Millar, Ewan K. A., Oakes, Samantha R., Chtanova, Tatyana, Swarbrick, Alexander, Naylor, Matthew J., O’Toole, Sandra, Green, Andrew R., Timpson, Paul, Gee, Julia M. W., Ellis, Ian O., Clark, Susan J., Ormandy, Christopher J.
Publicado 2015

Intravital FRAP Imaging using an E-cadherin-GFP Mouse Reveals Disease- and Drug-Dependent Dynamic Regulation of Cell-Cell Junctions in Live Tissue

por Erami, Zahra, Herrmann, David, Warren, Sean C., Nobis, Max, McGhee, Ewan J., Lucas, Morghan C., Leung, Wilfred, Reischmann, Nadine, Mrowinska, Agata, Schwarz, Juliane P., Kadir, Shereen, Conway, James R.W., Vennin, Claire, Karim, Saadia A., Campbell, Andrew D., Gallego-Ortega, David, Magenau, Astrid, Murphy, Kendelle J., Ridgway, Rachel A., Law, Andrew M., Walters, Stacey N., Grey, Shane T., Croucher, David R., Zhang, Lei, Herzog, Herbert, Hardeman, Edna C., Gunning, Peter W., Ormandy, Christopher J., Evans, T.R. Jeffry, Strathdee, Douglas, Sansom, Owen J., Morton, Jennifer P., Anderson, Kurt I., Timpson, Paul
Publicado 2015

Monitoring AKT activity and targeting in live tissue and disease contexts using a real-time Akt-FRET biosensor mouse

por Conway, James R. W., Warren, Sean C., Lee, Young-Kyung, McCulloch, Andrew T., Magenau, Astrid, Lee, Victoria, Metcalf, Xanthe L., Stoehr, Janett, Haigh, Katharina, Abdulkhalek, Lea, Guaman, Cristian S., Reed, Daniel A., Murphy, Kendelle J., Pereira, Brooke A., Mélénec, Pauline, Chambers, Cecilia, Latham, Sharissa L., Lenthall, Helen, Deenick, Elissa K., Ma, Yuanqing, Phan, Tri, Lim, Elgene, Joshua, Anthony M., Walters, Stacey, Grey, Shane T., Shi, Yan-Chuan, Zhang, Lei, Herzog, Herbert, Croucher, David R., Philp, Andy, Scheele, Colinda L.G.J., Herrmann, David, Sansom, Owen J., Morton, Jennifer P., Papa, Antonella, Haigh, Jody J., Nobis, Max, Timpson, Paul
Publicado 2023

Intravital imaging technology guides FAK-mediated priming in pancreatic cancer precision medicine according to Merlin status

por Murphy, Kendelle J., Reed, Daniel A., Vennin, Claire, Conway, James R. W., Nobis, Max, Yin, Julia X., Chambers, Cecilia R., Pereira, Brooke A., Lee, Victoria, Filipe, Elysse C., Trpceski, Michael, Ritchie, Shona, Lucas, Morghan C., Warren, Sean C., Skhinas, Joanna N., Magenau, Astrid, Metcalf, Xanthe L., Stoehr, Janett, Major, Gretel, Parkin, Ashleigh, Bidanel, Romain, Lyons, Ruth J., Zaratzian, Anaiis, Tayao, Michael, Da Silva, Andrew, Abdulkhalek, Lea, Gill, Anthony J., Johns, Amber L., Biankin, Andrew V., Samra, Jaswinder, Grimmond, Sean M., Chou, Angela, Goetz, Jacky G., Samuel, Michael S., Lyons, J. Guy, Burgess, Andrew, Caldon, C. Elizabeth, Horvath, Lisa G., Daly, Roger J., Gadegaard, Nikolaj, Wang, Yingxiao, Sansom, Owen J., Morton, Jennifer P., Cox, Thomas R., Pajic, Marina, Herrmann, David, Timpson, Paul
Publicado 2021