Welcome to ACS Bio & Med Chem Au

por Booker, Squire J., Conway, Stuart J., Lavasanifar, Afsaneh
Publicado 2021

The photochemical thiol–ene reaction as a versatile method for the synthesis of glutathione S-conjugates targeting the bacterial potassium efflux system Kef

por Healy, Jess, Rasmussen, Tim, Miller, Samantha, Booth, Ian R., Conway, Stuart J.
Publicado 2016

Two Color Imaging of Different Hypoxia Levels in Cancer Cells

por Wallabregue, Antoine L. D., Bolland, Hannah, Faulkner, Stephen, Hammond, Ester M., Conway, Stuart J.
Publicado 2023

Zap‐Pano: a Photocaged Prodrug of the KDAC Inhibitor Panobinostat

por Troelsen, Kathrin S., Calder, Ewen D. D., Skwarska, Anna, Sneddon, Deborah, Hammond, Ester M., Conway, Stuart J.
Publicado 2021

Development of isotope-enriched phosphatidylinositol-4- and 5-phosphate cellular mass spectrometry probes

por Joffrin, Amélie M., Saunders, Alex M., Barneda, David, Flemington, Vikki, Thompson, Amber L., Sanganee, Hitesh J., Conway, Stuart J.
Publicado 2020

Antibody-Based Imaging of Bioreductive Prodrug Release in Hypoxia

por Tosun, Çağla, Wallabregue, Antoine L. D., Mallerman, Maxim, Phillips, Sarah E., Edwards, Claire M., Conway, Stuart J., Hammond, Ester M.
Publicado 2023

CYP450 Enzymes Effect Oxygen-Dependent Reduction of Azide-Based Fluorogenic Dyes

por O’Connor, Liam J., Mistry, Ishna N., Collins, Sarah L., Folkes, Lisa K., Brown, Graham, Conway, Stuart J., Hammond, Ester M.
Publicado 2016

Engineering transkingdom signalling in plants to control gene expression in rhizosphere bacteria

por Geddes, Barney A., Paramasivan, Ponraj, Joffrin, Amelie, Thompson, Amber L., Christensen, Kirsten, Jorrin, Beatriz, Brett, Paul, Conway, Stuart J., Oldroyd, Giles E. D., Poole, Philip S.
Publicado 2019

Bioactivation of Isoxazole-Containing Bromodomain and Extra-Terminal Domain (BET) Inhibitors

por Flynn, Noah R., Ward, Michael D., Schleiff, Mary A., Laurin, Corentine M. C., Farmer, Rohit, Conway, Stuart J., Boysen, Gunnar, Swamidass, S. Joshua, Miller, Grover P.
Publicado 2021

3,5-Dimethylisoxazoles Act As Acetyl-lysine-mimetic Bromodomain Ligands

por Hewings, David S., Wang, Minghua, Philpott, Martin, Fedorov, Oleg, Uttarkar, Sagar, Filippakopoulos, Panagis, Picaud, Sarah, Vuppusetty, Chaitanya, Marsden, Brian, Knapp, Stefan, Conway, Stuart J., Heightman, Tom D.
Publicado 2011

Understanding the Structural Requirements for Activators of the Kef Bacterial Potassium Efflux System

por Healy, Jessica, Ekkerman, Silvia, Pliotas, Christos, Richard, Morgiane, Bartlett, Wendy, Grayer, Samuel C., Morris, Garrett M., Miller, Samantha, Booth, Ian R., Conway, Stuart J., Rasmussen, Tim
Publicado 2014

Bromodomain Factor 5 as a Target for Antileishmanial Drug Discovery

por Russell, Catherine N., Carter, Jennifer L., Borgia, Juliet M., Bush, Jacob, Calderón, Félix, Gabarró, Raquel, Conway, Stuart J., Mottram, Jeremy C., Wilkinson, Anthony J., Jones, Nathaniel G.
Publicado 2023

CH-01 is a Hypoxia-Activated Prodrug That Sensitizes Cells to Hypoxia/Reoxygenation Through Inhibition of Chk1 and Aurora A

por Cazares-Körner, Cindy, Pires, Isabel M., Swallow, I. Diane, Grayer, Samuel C., O’Connor, Liam J., Olcina, Monica M., Christlieb, Martin, Conway, Stuart J., Hammond, Ester M.
Publicado 2013

High-density functional-RNA arrays as a versatile platform for studying RNA-based interactions

por Phillips, Jack O, Butt, Louise E, Henderson, Charlotte A, Devonshire, Martin, Healy, Jess, Conway, Stuart J, Locker, Nicolas, Pickford, Andrew R, Vincent, Helen A, Callaghan, Anastasia J
Publicado 2018

Pharmacological Inhibition of ATR Can Block Autophagy through an ATR-Independent Mechanism

por Bowler, Elizabeth, Skwarska, Anna, Wilson, Joseph D., Ramachandran, Shaliny, Bolland, Hannah, Easton, Alistair, Ostheimer, Christian, Hwang, Ming-Shih, Leszczynska, Katarzyna B., Conway, Stuart J., Hammond, Ester M.
Publicado 2020

Development and pre-clinical testing of a novel hypoxia-activated KDAC inhibitor

por Skwarska, Anna, Calder, Ewen D.D., Sneddon, Deborah, Bolland, Hannah, Odyniec, Maria L., Mistry, Ishna N., Martin, Jennifer, Folkes, Lisa K., Conway, Stuart J., Hammond, Ester M.
Publicado 2021

Isoxazole‐Derived Amino Acids are Bromodomain‐Binding Acetyl‐Lysine Mimics: Incorporation into Histone H4 Peptides and Histone H3

por Sekirnik (née Measures), Angelina R., Hewings, David S., Theodoulou, Natalie H., Jursins, Lukass, Lewendon, Katie R., Jennings, Laura E., Rooney, Timothy P. C., Heightman, Tom D., Conway, Stuart J.
Publicado 2016

Bcl-2 functionally interacts with inositol 1,4,5-trisphosphate receptors to regulate calcium release from the ER in response to inositol 1,4,5-trisphosphate

por Chen, Rui, Valencia, Ignacio, Zhong, Fei, McColl, Karen S., Roderick, H. Llewelyn, Bootman, Martin D., Berridge, Michael J., Conway, Stuart J., Holmes, Andrew B., Mignery, Gregory A., Velez, Patricio, Distelhorst, Clark W.
Publicado 2004

NAADP Activates Two-Pore Channels on T Cell Cytolytic Granules to Stimulate Exocytosis and Killing

por Davis, Lianne C., Morgan, Anthony J., Chen, Ji-Li, Snead, Charlotte M., Bloor-Young, Duncan, Shenderov, Eugene, Stanton-Humphreys, Megan N., Conway, Stuart J., Churchill, Grant C., Parrington, John, Cerundolo, Vincenzo, Galione, Antony
Publicado 2012

A Single‐Stranded DNA‐Encoded Chemical Library Based on a Stereoisomeric Scaffold Enables Ligand Discovery by Modular Assembly of Building Blocks

por Bassi, Gabriele, Favalli, Nicholas, Vuk, Miriam, Catalano, Marco, Martinelli, Adriano, Trenner, Anika, Porro, Antonio, Yang, Su, Tham, Chuin Lean, Moroglu, Mustafa, Yue, Wyatt W., Conway, Stuart J., Vogt, Peter K., Sartori, Alessandro A., Scheuermann, Jörg, Neri, Dario
Publicado 2020