Structure of Microtubule-Trapped Human Kinesin-5 and Its Mechanism of Inhibition Revealed Using Cryoelectron Microscopy

por Peña, Alejandro, Sweeney, Aaron, Cook, Alexander D., Topf, Maya, Moores, Carolyn A.
Publicado 2020

A microtubule RELION-based pipeline for cryo-EM image processing

por Cook, Alexander D., Manka, Szymon W., Wang, Su, Moores, Carolyn A., Atherton, Joseph
Publicado 2020

Structure of Microtubule-Trapped Human Kinesin-5 and Its Mechanism of Inhibition Revealed Using Cryoelectron Microscopy

por Peña, Alejandro, Sweeney, Aaron, Cook, Alexander D., Locke, Julia, Topf, Maya, Moores, Carolyn A.
Publicado 2021

Cryo-EM structure of a microtubule-bound parasite kinesin motor and implications for its mechanism and inhibition

por Cook, Alexander D., Roberts, Anthony J., Atherton, Joseph, Tewari, Rita, Topf, Maya, Moores, Carolyn A.
Publicado 2021

Mechanochemical tuning of a kinesin motor essential for malaria parasite transmission

por Liu, Tianyang, Shilliday, Fiona, Cook, Alexander D., Zeeshan, Mohammad, Brady, Declan, Tewari, Rita, Sutherland, Colin J., Roberts, Anthony J., Moores, Carolyn A.
Publicado 2022

Author Correction: Mechanochemical tuning of a kinesin motor essential for malaria parasite transmission

por Liu, Tianyang, Shilliday, Fiona, Cook, Alexander D., Zeeshan, Mohammad, Brady, Declan, Tewari, Rita, Sutherland, Colin J., Roberts, Anthony J., Moores, Carolyn A.
Publicado 2023

Inhibiting parasite proliferation using a rationally designed anti‐tubulin agent

por Gaillard, Natacha, Sharma, Ashwani, Abbaali, Izra, Liu, Tianyang, Shilliday, Fiona, Cook, Alexander D, Ehrhard, Valentin, Bangera, Mamata, Roberts, Anthony J, Moores, Carolyn A, Morrissette, Naomi, Steinmetz, Michel O
Publicado 2021

Structural determinants of microtubule minus end preference in CAMSAP CKK domains

por Atherton, Joseph, Luo, Yanzhang, Xiang, Shengqi, Yang, Chao, Rai, Ankit, Jiang, Kai, Stangier, Marcel, Vemu, Annapurna, Cook, Alexander D., Wang, Su, Roll-Mecak, Antonina, Steinmetz, Michel O., Akhmanova, Anna, Baldus, Marc, Moores, Carolyn A.
Publicado 2019

Invariant surface glycoprotein 65 of Trypanosoma brucei is a complement C3 receptor

por Macleod, Olivia J. S., Cook, Alexander D., Webb, Helena, Crow, Mandy, Burns, Roisin, Redpath, Maria, Seisenberger, Stefanie, Trevor, Camilla E., Peacock, Lori, Schwede, Angela, Kimblin, Nicola, Francisco, Amanda F., Pepperl, Julia, Rust, Steve, Voorheis, Paul, Gibson, Wendy, Taylor, Martin C., Higgins, Matthew K., Carrington, Mark
Publicado 2022