Reciprocal feedback inhibition of the androgen receptor and PI3K as a novel therapy for castrate-sensitive and -resistant prostate cancer

por Qi, Wenqing, Morales, Carla, Cooke, Laurence S., Johnson, Benny, Somer, Bradley, Mahadevan, Daruka
Publicado 2015

The c-Met receptor tyrosine kinase inhibitor MP470 radiosensitizes glioblastoma cells

por Welsh, James W, Mahadevan, Daruka, Ellsworth, Ron, Cooke, Laurence, Bearss, David, Stea, Baldassarre
Publicado 2009

Co-targeting aurora kinase with PD-L1 and PI3K abrogates immune checkpoint mediated proliferation in peripheral T-cell lymphoma: a novel therapeutic strategy

por Islam, Shariful, Vick, Eric, Huber, Bryan, Morales, Carla, Spier, Catherine, Cooke, Laurence, Weterings, Eric, Mahadevan, Daruka
Publicado 2017

TP53 Mutations as a Driver of Metastasis Signaling in Advanced Cancer Patients

por Pandey, Ritu, Johnson, Nathan, Cooke, Laurence, Johnson, Benny, Chen, Yuliang, Pandey, Manjari, Chandler, Jason, Mahadevan, Daruka
Publicado 2021

Drug-induced aneuploidy and polyploidy is a mechanism of disease relapse in MYC/BCL2-addicted diffuse large B-cell lymphoma

por Islam, Shariful, Paek, Andrew L., Hammer, Michael, Rangarajan, Savithri, Ruijtenbeek, Robert, Cooke, Laurence, Weterings, Eric, Mahadevan, Daruka
Publicado 2018

Novel receptor tyrosine kinase targeted combination therapies for imatinib-resistant gastrointestinal stromal tumors (GIST)

por Mahadevan, Daruka, Theiss, Noah, Morales, Carla, Stejskal, Amy E., Cooke, Laurence S., Zhu, Min, Kurtzman, Drew, Swart, Rachel, Ong, Evan, Qi, Wenqing
Publicado 2014

Gene Expression and Serum Cytokine Profiling of Low Stage CLL Identify WNT/PCP, Flt-3L/Flt-3 and CXCL9/CXCR3 as Regulators of Cell Proliferation, Survival and Migration

por Mahadevan, Daruka, Choi, James, Cooke, Laurence, Simons, Bram, Riley, Christopher, Klinkhammer, Thomas, Sud, Rohit, Maddipoti, Sirisha, Hehn, Sean, Garewal, Harinder, Spier, Catherine
Publicado 2009

Alisertib Added to Rituximab and Vincristine Is Synthetic Lethal and Potentially Curative in Mice with Aggressive DLBCL Co-Overexpressing MYC and BCL2

por Mahadevan, Daruka, Morales, Carla, Cooke, Laurence S., Manziello, Ann, Mount, David W., Persky, Daniel O., Fisher, Richard I., Miller, Thomas P., Qi, Wenqing
Publicado 2014

Carcinoembryonic antigen cell adhesion molecule 6 (CEACAM6) in Pancreatic Ductal Adenocarcinoma (PDA): An integrative analysis of a novel therapeutic target

por Pandey, Ritu, Zhou, Muhan, Islam, Shariful, Chen, Baowei, Barker, Natalie K, Langlais, Paul, Srivastava, Anup, Luo, Moulun, Cooke, Laurence S., Weterings, Eric, Mahadevan, Daruka
Publicado 2019