Defining the clinical genomic landscape for real-world precision oncology

por Beer, Philip A., Cooke, Susanna L., Chang, David K., Biankin, Andrew V.
Publicado 2020

High-resolution array CGH clarifies events occurring on 8p in carcinogenesis

por Cooke, Susanna L, Pole, Jessica CM, Chin, Suet-Feung, Ellis, Ian O, Caldas, Carlos, Edwards, Paul AW
Publicado 2008

Myocarditis and/or pericarditis risk after mRNA COVID-19 vaccination: A Canadian head to head comparison of BNT162b2 and mRNA-1273 vaccines

por Abraham, Natalia, Spruin, Sarah, Rossi, Tanya, Fireman, Bruce, Zafack, Joseline, Blaser, Christine, Shaw, Amanda, Hutchings, Kimberley, Ogunnaike-Cooke, Susanna
Publicado 2022

Genomic analysis of genetic heterogeneity and evolution in high-grade serous ovarian carcinoma

por Cooke, Susanna L, Ng, Charlotte KY, Melnyk, Nataliya, Garcia, Maria J, Hardcastle, Tom, Temple, Jillian, Langdon, Simon, Huntsman, David, Brenton, James D
Publicado 2010

C. elegans whole-genome sequencing reveals mutational signatures related to carcinogens and DNA repair deficiency

por Meier, Bettina, Cooke, Susanna L., Weiss, Joerg, Bailly, Aymeric P., Alexandrov, Ludmil B., Marshall, John, Raine, Keiran, Maddison, Mark, Anderson, Elizabeth, Stratton, Michael R., Gartner, Anton, Campbell, Peter J.
Publicado 2014

The Specificity of the FOXL2 c.402C>G Somatic Mutation: A Survey of Solid Tumors

por Schrader, Kasmintan A., Gorbatcheva, Bella, Senz, Janine, Heravi-Moussavi, Alireza, Melnyk, Nataliya, Salamanca, Clara, Maines-Bandiera, Sarah, Cooke, Susanna L., Leung, Peter, Brenton, James D., Gilks, C. Blake, Monahan, John, Huntsman, David G.
Publicado 2009

Structural analysis of the genome of breast cancer cell line ZR-75-30 identifies twelve expressed fusion genes

por Schulte, Ina, Batty, Elizabeth M, Pole, Jessica CM, Blood, Katherine A, Mo, Steven, Cooke, Susanna L, Ng, Charlotte, Howe, Kevin L, Chin, Suet-Feung, Brenton, James D, Caldas, Carlos, Howarth, Karen D, Edwards, Paul AW
Publicado 2012

NRG1 fusions in breast cancer

por Howarth, Karen D., Mirza, Tashfina, Cooke, Susanna L., Chin, Suet-Feung, Pole, Jessica C., Turro, Ernest, Eldridge, Matthew D., Garcia, Raquel Manzano, Rueda, Oscar M., Boursnell, Chris, Abraham, Jean E., Caldas, Carlos, Edwards, Paul A. W.
Publicado 2021

Spatial and Temporal Heterogeneity in High-Grade Serous Ovarian Cancer: A Phylogenetic Analysis

por Schwarz, Roland F., Ng, Charlotte K. Y., Cooke, Susanna L., Newman, Scott, Temple, Jillian, Piskorz, Anna M., Gale, Davina, Sayal, Karen, Murtaza, Muhammed, Baldwin, Peter J., Rosenfeld, Nitzan, Earl, Helena M., Sala, Evis, Jimenez-Linan, Mercedes, Parkinson, Christine A., Markowetz, Florian, Brenton, James D.
Publicado 2015

Molecular subclusters of follicular lymphoma: a report from the United Kingdom’s Haematological Malignancy Research Network

por Crouch, Simon, Painter, Daniel, Barrans, Sharon L., Roman, Eve, Beer, Philip A., Cooke, Susanna L., Glover, Paul, Van Hoppe, Suzan J.L., Webster, Nichola, Lacy, Stuart E., Ruiz, Camilo, Campbell, Peter J., Hodson, Daniel J., Patmore, Russell, Burton, Cathy, Smith, Alexandra, Tooze, Reuben M.
Publicado 2022

Genetic modification of primary human B cells to model high-grade lymphoma

por Caeser, Rebecca, Di Re, Miriam, Krupka, Joanna A., Gao, Jie, Lara-Chica, Maribel, Dias, João M. L., Cooke, Susanna L., Fenner, Rachel, Usheva, Zelvera, Runge, Hendrik F. P., Beer, Philip A., Eldaly, Hesham, Pak, Hyo-Kyung, Park, Chan-Sik, Vassiliou, George S., Huntly, Brian J. P., Mupo, Annalisa, Bashford-Rogers, Rachael J. M., Hodson, Daniel J.
Publicado 2019

Tandem duplication of chromosomal segments is common in ovarian and breast cancer genomes

por McBride, David J, Etemadmoghadam, Dariush, Cooke, Susanna L, Alsop, Kathryn, George, Joshy, Butler, Adam, Cho, Juok, Galappaththige, Danushka, Greenman, Chris, Howarth, Karen D, Lau, King W, Ng, Charlotte K, Raine, Keiran, Teague, Jon, Wedge, David C, Cancer Study Group, Australian Ovarian, Caubit, Xavier, Stratton, Michael R, Brenton, James D, Campbell, Peter J, Futreal, P Andrew, Bowtell, David DL
Publicado 2012

Single-cell paired-end genome sequencing reveals structural variation per cell cycle

por Voet, Thierry, Kumar, Parveen, Van Loo, Peter, Cooke, Susanna L., Marshall, John, Lin, Meng-Lay, Zamani Esteki, Masoud, Van der Aa, Niels, Mateiu, Ligia, McBride, David J., Bignell, Graham R., McLaren, Stuart, Teague, Jon, Butler, Adam, Raine, Keiran, Stebbings, Lucy A., Quail, Michael A., D’Hooghe, Thomas, Moreau, Yves, Futreal, P. Andrew, Stratton, Michael R., Vermeesch, Joris R., Campbell, Peter J.
Publicado 2013

Mutational signatures of ionizing radiation in second malignancies

por Behjati, Sam, Gundem, Gunes, Wedge, David C., Roberts, Nicola D., Tarpey, Patrick S., Cooke, Susanna L., Van Loo, Peter, Alexandrov, Ludmil B., Ramakrishna, Manasa, Davies, Helen, Nik-Zainal, Serena, Hardy, Claire, Latimer, Calli, Raine, Keiran M., Stebbings, Lucy, Menzies, Andy, Jones, David, Shepherd, Rebecca, Butler, Adam P., Teague, Jon W., Jorgensen, Mette, Khatri, Bhavisha, Pillay, Nischalan, Shlien, Adam, Futreal, P. Andrew, Badie, Christophe, McDermott, Ultan, Bova, G. Steven, Richardson, Andrea L., Flanagan, Adrienne M., Stratton, Michael R., Campbell, Peter J.
Publicado 2016

Recurrent mutation of IGF signalling genes and distinct patterns of genomic rearrangement in osteosarcoma

por Behjati, Sam, Tarpey, Patrick S., Haase, Kerstin, Ye, Hongtao, Young, Matthew D., Alexandrov, Ludmil B., Farndon, Sarah J., Collord, Grace, Wedge, David C., Martincorena, Inigo, Cooke, Susanna L., Davies, Helen, Mifsud, William, Lidgren, Mathias, Martin, Sancha, Latimer, Calli, Maddison, Mark, Butler, Adam P., Teague, Jon W., Pillay, Nischalan, Shlien, Adam, McDermott, Ultan, Futreal, P. Andrew, Baumhoer, Daniel, Zaikova, Olga, Bjerkehagen, Bodil, Myklebost, Ola, Amary, M. Fernanda, Tirabosco, Roberto, Van Loo, Peter, Stratton, Michael R., Flanagan, Adrienne M., Campbell, Peter J.
Publicado 2017

Epithelial-to-Mesenchymal Transition Supports Ovarian Carcinosarcoma Tumorigenesis and Confers Sensitivity to Microtubule Targeting with Eribulin

por Ho, Gwo Yaw, Kyran, Elizabeth L., Bedo, Justin, Wakefield, Matthew J., Ennis, Darren P., Mirza, Hasan B., Vandenberg, Cassandra J., Lieschke, Elizabeth, Farrell, Andrew, Hadla, Anthony, Lim, Ratana, Dall, Genevieve, Vince, James E., Chua, Ngee Kiat, Kondrashova, Olga, Upstill-Goddard, Rosanna, Bailey, Ulla-Maja, Dowson, Suzanne, Roxburgh, Patricia, Glasspool, Rosalind M., Bryson, Gareth, Biankin, Andrew V., Cooke, Susanna L., Ratnayake, Gayanie, McNally, Orla, Traficante, Nadia, DeFazio, Anna, Weroha, S. John, Bowtell, David D., McNeish, Iain A., Papenfuss, Anthony T., Scott, Clare L., Barker, Holly E.
Publicado 2022

Direct Transcriptional Consequences of Somatic Mutation in Breast Cancer

por Shlien, Adam, Raine, Keiran, Fuligni, Fabio, Arnold, Roland, Nik-Zainal, Serena, Dronov, Serge, Mamanova, Lira, Rosic, Andrej, Ju, Young Seok, Cooke, Susanna L., Ramakrishna, Manasa, Papaemmanuil, Elli, Davies, Helen R., Tarpey, Patrick S., Van Loo, Peter, Wedge, David C., Jones, David R., Martin, Sancha, Marshall, John, Anderson, Elizabeth, Hardy, Claire, Barbashina, Violetta, Aparicio, Samuel A.J.R., Sauer, Torill, Garred, Øystein, Vincent-Salomon, Anne, Mariani, Odette, Boyault, Sandrine, Fatima, Aquila, Langerød, Anita, Borg, Åke, Thomas, Gilles, Richardson, Andrea L., Børresen-Dale, Anne-Lise, Polyak, Kornelia, Stratton, Michael R., Campbell, Peter J.
Publicado 2016

Precision Oncology in Surgery: Patient Selection for Operable Pancreatic Cancer

por Dreyer, Stephan B., Pinese, Mark, Jamieson, Nigel B., Scarlett, Christopher J., Colvin, Emily K., Pajic, Marina, Johns, Amber L., Humphris, Jeremy L., Wu, Jianmin, Cowley, Mark J., Chou, Angela, Nagrial, Adnan M., Chantrill, Lorraine, Chin, Venessa T., Jones, Marc D., Moran-Jones, Kim, Carter, Christopher Ross, Dickson, Euan J., Samra, Jaswinder S., Merrett, Neil D., Gill, Anthony J., Kench, James G., Duthie, Fraser, Miller, David K., Cooke, Susanna, Aust, Daniela, Knösel, Thomas, Rümmele, Petra, Grützmann, Robert, Pilarsky, Christian, Nguyen, Nam Q., Musgrove, Elizabeth A., Bailey, Peter J., McKay, Colin J., Biankin, Andrew V., Chang, David K.
Publicado 2020

Processed pseudogenes acquired somatically during cancer development

por Cooke, Susanna L., Shlien, Adam, Marshall, John, Pipinikas, Christodoulos P., Martincorena, Inigo, Tubio, Jose M.C., Li, Yilong, Menzies, Andrew, Mudie, Laura, Ramakrishna, Manasa, Yates, Lucy, Davies, Helen, Bolli, Niccolo, Bignell, Graham R., Tarpey, Patrick S., Behjati, Sam, Nik-Zainal, Serena, Papaemmanuil, Elli, Teixeira, Vitor H., Raine, Keiran, O’Meara, Sarah, Dodoran, Maryam S., Teague, Jon W., Butler, Adam P., Iacobuzio-Donahue, Christine, Santarius, Thomas, Grundy, Richard G., Malkin, David, Greaves, Mel, Munshi, Nikhil, Flanagan, Adrienne M., Bowtell, David, Martin, Sancha, Larsimont, Denis, Reis-Filho, Jorge S., Boussioutas, Alex, Taylor, Jack A., Hayes, Neil D., Janes, Sam M., Futreal, P. Andrew, Stratton, Michael R., McDermott, Ultan, Campbell, Peter J.
Publicado 2014

Recurrent PTPRB and PLCG1 mutations in angiosarcoma

por Behjati, Sam, Tarpey, Patrick S, Sheldon, Helen, Martincorena, Inigo, Van Loo, Peter, Gundem, Gunes, Wedge, David C, Ramakrishna, Manasa, Cooke, Susanna L, Pillay, Nischalan, Vollan, Hans Kristian M, Papaemmanuil, Elli, Koss, Hans, Bunney, Tom D, Hardy, Claire, Joseph, Olivia R, Martin, Sancha, Mudie, Laura, Butler, Adam, Teague, Jon W, Patil, Meena, Steers, Graham, Cao, Yu, Gumbs, Curtis, Ingram, Davis, Lazar, Alexander J, Little, Latasha, Mahadeshwar, Harshad, Protopopov, Alexei, Al Sannaa, Ghadah A, Seth, Sahil, Song, Xingzhi, Tang, Jiabin, Zhang, Jianhua, Ravi, Vinod, Torres, Keila E, Khatri, Bhavisha, Halai, Dina, Roxanis, Ioannis, Baumhoer, Daniel, Tirabosco, Roberto, Amary, M Fernanda, Boshoff, Chris, McDermott, Ultan, Katan, Matilda, Stratton, Michael R, Futreal, P Andrew, Flanagan, Adrienne M, Harris, Adrian, Campbell, Peter J
Publicado 2014