Upregulation of Glucose Uptake and Hexokinase Activity of Primary Human CD4+ T Cells in Response to Infection with HIV-1

por Kavanagh Williamson, Maia, Coombes, Naomi, Juszczak, Florian, Athanasopoulos, Marios, Khan, Mariam B., Eykyn, Thomas R., Srenathan, Ushani, Taams, Leonie S., Dias Zeidler, Julianna, Da Poian, Andrea T., Huthoff, Hendrik
Publicado 2018

Assessment of the Biological Impact of SARS-CoV-2 Genetic Variation Using an Authentic Virus Neutralisation Assay with Convalescent Plasma, Vaccinee Sera, and Standard Reagents

por Coombes, Naomi S., Bewley, Kevin R., Le Duff, Yann, Hurley, Matthew, Smith, Lauren J., Weldon, Thomas M., Osman, Karen, Pullan, Steven, Berry, Neil, Hallis, Bassam, Charlton, Sue, Hall, Yper, Funnell, Simon G. P.
Publicado 2023

The Omicron Sub-Variant BA.4 Displays a Remarkable Lack of Clinical Signs in a Golden Syrian Hamster Model of SARS-CoV-2 Infection

por Davies, Elizabeth R., Ryan, Kathryn A., Bewley, Kevin R., Coombes, Naomi S., Salguero, Francisco J., Carnell, Oliver T., Biddlecombe, Sarah, Charlton, Michael, Challis, Amy, Cross, Eleanor S., Handley, Alastair, Ngabo, Didier, Weldon, Thomas M., Hall, Yper, Funnell, Simon G. P.
Publicado 2023

SARS-CoV-2 Disease Severity in the Golden Syrian Hamster Model of Infection Is Related to the Volume of Intranasal Inoculum

por Handley, Alastair, Ryan, Kathryn A., Davies, Elizabeth R., Bewley, Kevin R., Carnell, Oliver T., Challis, Amy, Coombes, Naomi S., Fotheringham, Susan A., Gooch, Karen E., Charlton, Michael, Harris, Debbie J., Kennard, Chelsea, Ngabo, Didier, Weldon, Thomas M., Salguero, Francisco J., Funnell, Simon G. P., Hall, Yper
Publicado 2023

mRNA vaccination in people over 80 years of age induces strong humoral immune responses against SARS-CoV-2 with cross neutralization of P.1 Brazilian variant

por Parry, Helen, Tut, Gokhan, Bruton, Rachel, Faustini, Sian, Stephens, Christine, Saunders, Philip, Bentley, Christopher, Hilyard, Katherine, Brown, Kevin, Amirthalingam, Gayatri, Charlton, Sue, Leung, Stephanie, Chiplin, Emily, Coombes, Naomi S, Bewley, Kevin R, Penn, Elizabeth J, Rowe, Cathy, Otter, Ashley, Watts, Rosie, D'Arcangelo, Silvia, Hallis, Bassam, Makin, Andrew, Richter, Alex, Zuo, Jianmin, Moss, Paul
Publicado 2021

Unfractionated heparin inhibits live wild type SARS‐CoV‐2 cell infectivity at therapeutically relevant concentrations

por Tree, Julia A., Turnbull, Jeremy E., Buttigieg, Karen R., Elmore, Michael J., Coombes, Naomi, Hogwood, John, Mycroft‐West, Courtney J., Lima, Marcelo A., Skidmore, Mark A., Karlsson, Richard, Chen, Yen‐Hsi, Yang, Zhang, Spalluto, Cosma Mirella, Staples, Karl J., Yates, Edwin A., Gray, Elaine, Singh, Dave, Wilkinson, Tom, Page, Clive P., Carroll, Miles W.
Publicado 2020

A cross-reactive human IgA monoclonal antibody blocks SARS-CoV-2 spike-ACE2 interaction

por Ejemel, Monir, Li, Qi, Hou, Shurong, Schiller, Zachary A., Tree, Julia A., Wallace, Aaron, Amcheslavsky, Alla, Kurt Yilmaz, Nese, Buttigieg, Karen R., Elmore, Michael J., Godwin, Kerry, Coombes, Naomi, Toomey, Jacqueline R., Schneider, Ryan, Ramchetty, Anudeep S., Close, Brianna J., Chen, Da-Yuan, Conway, Hasahn L., Saeed, Mohsan, Ganesa, Chandrashekar, Carroll, Miles W., Cavacini, Lisa A., Klempner, Mark S., Schiffer, Celia A., Wang, Yang
Publicado 2020

Neutralization of SARS-CoV-2 by Destruction of the Prefusion Spike

por Huo, Jiandong, Zhao, Yuguang, Ren, Jingshan, Zhou, Daming, Duyvesteyn, Helen M.E., Ginn, Helen M., Carrique, Loic, Malinauskas, Tomas, Ruza, Reinis R., Shah, Pranav N.M., Tan, Tiong Kit, Rijal, Pramila, Coombes, Naomi, Bewley, Kevin R., Tree, Julia A., Radecke, Julika, Paterson, Neil G., Supasa, Piyada, Mongkolsapaya, Juthathip, Screaton, Gavin R., Carroll, Miles, Townsend, Alain, Fry, Elizabeth E., Owens, Raymond J., Stuart, David I.
Publicado 2020

Author Correction: Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2

por Huo, Jiangdong, Le Bas, Audrey, Ruza, Reinis R., Duyvesteyn, Helen M. E., Mikolajek, Halina, Malinauskas, Tomas, Tan, Tiong Kit, Rijal, Pramila, Dumoux, Maud, Ward, Philip N., Ren, Jingshan, Zhou, Daming, Harrison, Peter J., Weckener, Miriam, Clare, Daniel K., Vogirala, Vinod K., Radecke, Julika, Moynié, Lucile, Zhao, Yuguang, Gilbert-Jaramillo, Javier, Knight, Michael L., Tree, Julia A., Buttigieg, Karen R., Coombes, Naomi, Elmore, Michael J., Carroll, Miles W., Carrique, Loic, Shah, Pranav N. M., James, William, Townsend, Alain R., Stuart, David I., Owens, Raymond J., Naismith, James H.
Publicado 2020

Author Correction: Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2

por Huo, Jiandong, Bas, Audrey Le, Ruza, Reinis R., Duyvesteyn, Helen M. E., Mikolajek, Halina, Malinauskas, Tomas, Tan, Tiong Kit, Rijal, Pramila, Dumoux, Maud, Ward, Philip N., Ren, Jingshan, Zhou, Daming, Harrison, Peter J., Weckener, Miriam, Clare, Daniel K., Vogirala, Vinod K., Radecke, Julika, Moynié, Lucile, Zhao, Yuguang, Gilbert-Jaramillo, Javier, Knight, Michael L., Tree, Julia A., Buttigieg, Karen R., Coombes, Naomi, Elmore, Michael J., Carroll, Miles W., Carrique, Loic, Shah, Pranav N. M., James, William, Townsend, Alain R., Stuart, David I., Owens, Raymond J., Naismith, James H.
Publicado 2021

Syrian hamster convalescence from prototype SARS-CoV-2 confers measurable protection against the attenuated disease caused by the Omicron variant

por Ryan, Kathryn A., Bewley, Kevin R., Watson, Robert J., Burton, Christopher, Carnell, Oliver, Cavell, Breeze E., Challis, Amy, Coombes, Naomi S., Davies, Elizabeth R., Edun-Huges, Jack, Emery, Kirsty, Fell, Rachel, Fotheringham, Susan A., Gooch, Karen E., Gowan, Kathryn, Handley, Alastair, Harris, Debbie J., Hesp, Richard, Hunter, Laura, Humphreys, Richard, Johnson, Rachel, Kennard, Chelsea, Knott, Daniel, Lister, Sian, Morley, Daniel, Ngabo, Didier, Osman, Karen L., Paterson, Jemma, Penn, Elizabeth J., Pullan, Steven T., Richards, Kevin S., Summers, Sian, Thomas, Stephen R., Weldon, Thomas, Wiblin, Nathan R., Rayner, Emma L., Vipond, Richard T., Hallis, Bassam, Salguero, Francisco J., Funnell, Simon G. P., Hall, Yper
Publicado 2023

Evidence of escape of SARS-CoV-2 variant B.1.351 from natural and vaccine-induced sera

por Zhou, Daming, Dejnirattisai, Wanwisa, Supasa, Piyada, Liu, Chang, Mentzer, Alexander J., Ginn, Helen M., Zhao, Yuguang, Duyvesteyn, Helen M.E., Tuekprakhon, Aekkachai, Nutalai, Rungtiwa, Wang, Beibei, Paesen, Guido C., Lopez-Camacho, Cesar, Slon-Campos, Jose, Hallis, Bassam, Coombes, Naomi, Bewley, Kevin, Charlton, Sue, Walter, Thomas S., Skelly, Donal, Lumley, Sheila F., Dold, Christina, Levin, Robert, Dong, Tao, Pollard, Andrew J., Knight, Julian C., Crook, Derrick, Lambe, Teresa, Clutterbuck, Elizabeth, Bibi, Sagida, Flaxman, Amy, Bittaye, Mustapha, Belij-Rammerstorfer, Sandra, Gilbert, Sarah, James, William, Carroll, Miles W., Klenerman, Paul, Barnes, Eleanor, Dunachie, Susanna J., Fry, Elizabeth E., Mongkolsapaya, Juthathip, Ren, Jingshan, Stuart, David I., Screaton, Gavin R.
Publicado 2021

Synthetic Heparan Sulfate Mimetic Pixatimod (PG545) Potently Inhibits SARS-CoV-2 by Disrupting the Spike–ACE2 Interaction

por Guimond, Scott E., Mycroft-West, Courtney J., Gandhi, Neha S., Tree, Julia A., Le, Thuy T., Spalluto, C. Mirella, Humbert, Maria V., Buttigieg, Karen R., Coombes, Naomi, Elmore, Michael J., Wand, Matthew, Nyström, Kristina, Said, Joanna, Setoh, Yin Xiang, Amarilla, Alberto A., Modhiran, Naphak, Sng, Julian D. J., Chhabra, Mohit, Young, Paul R., Rawle, Daniel J., Lima, Marcelo A., Yates, Edwin A., Karlsson, Richard, Miller, Rebecca L., Chen, Yen-Hsi, Bagdonaite, Ieva, Yang, Zhang, Stewart, James, Nguyen, Dung, Laidlaw, Stephen, Hammond, Edward, Dredge, Keith, Wilkinson, Tom M. A., Watterson, Daniel, Khromykh, Alexander A., Suhrbier, Andreas, Carroll, Miles W., Trybala, Edward, Bergström, Tomas, Ferro, Vito, Skidmore, Mark A., Turnbull, Jeremy E.
Publicado 2022

Reduced neutralization of SARS-CoV-2 B.1.1.7 variant by convalescent and vaccine sera

por Supasa, Piyada, Zhou, Daming, Dejnirattisai, Wanwisa, Liu, Chang, Mentzer, Alexander J., Ginn, Helen M., Zhao, Yuguang, Duyvesteyn, Helen M.E., Nutalai, Rungtiwa, Tuekprakhon, Aekkachai, Wang, Beibei, Paesen, Guido C., Slon-Campos, Jose, López-Camacho, César, Hallis, Bassam, Coombes, Naomi, Bewley, Kevin R., Charlton, Sue, Walter, Thomas S., Barnes, Eleanor, Dunachie, Susanna J., Skelly, Donal, Lumley, Sheila F., Baker, Natalie, Shaik, Imam, Humphries, Holly E., Godwin, Kerry, Gent, Nick, Sienkiewicz, Alex, Dold, Christina, Levin, Robert, Dong, Tao, Pollard, Andrew J., Knight, Julian C., Klenerman, Paul, Crook, Derrick, Lambe, Teresa, Clutterbuck, Elizabeth, Bibi, Sagida, Flaxman, Amy, Bittaye, Mustapha, Belij-Rammerstorfer, Sandra, Gilbert, Sarah, Hall, David R., Williams, Mark A., Paterson, Neil G., James, William, Carroll, Miles W., Fry, Elizabeth E., Mongkolsapaya, Juthathip, Ren, Jingshan, Stuart, David I., Screaton, Gavin R.
Publicado 2021

Dose-dependent response to infection with SARS-CoV-2 in the ferret model and evidence of protective immunity

por Ryan, Kathryn A., Bewley, Kevin R., Fotheringham, Susan A., Slack, Gillian S., Brown, Phillip, Hall, Yper, Wand, Nadina I., Marriott, Anthony C., Cavell, Breeze E., Tree, Julia A., Allen, Lauren, Aram, Marilyn J., Bean, Thomas J., Brunt, Emily, Buttigieg, Karen R., Carter, Daniel P., Cobb, Rebecca, Coombes, Naomi S., Findlay-Wilson, Steve J., Godwin, Kerry J., Gooch, Karen E., Gouriet, Jade, Halkerston, Rachel, Harris, Debbie J., Hender, Thomas H., Humphries, Holly E., Hunter, Laura, Ho, Catherine M. K., Kennard, Chelsea L., Leung, Stephanie, Longet, Stephanie, Ngabo, Didier, Osman, Karen L., Paterson, Jemma, Penn, Elizabeth J., Pullan, Steven T., Rayner, Emma, Skinner, Oliver, Steeds, Kimberley, Taylor, Irene, Tipton, Tom, Thomas, Stephen, Turner, Carrie, Watson, Robert J., Wiblin, Nathan R., Charlton, Sue, Hallis, Bassam, Hiscox, Julian A., Funnell, Simon, Dennis, Mike J., Whittaker, Catherine J., Catton, Michael G., Druce, Julian, Salguero, Francisco J., Carroll, Miles W.
Publicado 2021

Comparison of rhesus and cynomolgus macaques as an infection model for COVID-19

por Salguero, Francisco J., White, Andrew D., Slack, Gillian S., Fotheringham, Susan A., Bewley, Kevin R., Gooch, Karen E., Longet, Stephanie, Humphries, Holly E., Watson, Robert J., Hunter, Laura, Ryan, Kathryn A., Hall, Yper, Sibley, Laura, Sarfas, Charlotte, Allen, Lauren, Aram, Marilyn, Brunt, Emily, Brown, Phillip, Buttigieg, Karen R., Cavell, Breeze E., Cobb, Rebecca, Coombes, Naomi S., Darby, Alistair, Daykin-Pont, Owen, Elmore, Michael J., Garcia-Dorival, Isabel, Gkolfinos, Konstantinos, Godwin, Kerry J., Gouriet, Jade, Halkerston, Rachel, Harris, Debbie J., Hender, Thomas, Ho, Catherine M. K., Kennard, Chelsea L., Knott, Daniel, Leung, Stephanie, Lucas, Vanessa, Mabbutt, Adam, Morrison, Alexandra L., Nelson, Charlotte, Ngabo, Didier, Paterson, Jemma, Penn, Elizabeth J., Pullan, Steve, Taylor, Irene, Tipton, Tom, Thomas, Stephen, Tree, Julia A., Turner, Carrie, Vamos, Edith, Wand, Nadina, Wiblin, Nathan R., Charlton, Sue, Dong, Xiaofeng, Hallis, Bassam, Pearson, Geoffrey, Rayner, Emma L., Nicholson, Andrew G., Funnell, Simon G., Hiscox, Julian A., Dennis, Mike J., Gleeson, Fergus V., Sharpe, Sally, Carroll, Miles W.
Publicado 2021