Unmasking BCL-2 Addiction in Synovial Sarcoma by Overcoming Low NOXA

por Fairchild, Carter K., Floros, Konstantinos V., Jacob, Sheeba, Coon, Colin M., Puchalapalli, Madhavi, Hu, Bin, Harada, Hisashi, Dozmorov, Mikhail G., Koblinski, Jennifer E., Smith, Steven C., Domson, Gregory, Leverson, Joel D., Souers, Andrew J., Takebe, Naoko, Ebi, Hiromichi, Faber, Anthony C., Boikos, Sosipatros A.
Publicado 2021

High-risk neuroblastoma with NF1 loss of function is targetable using SHP2 inhibition

por Cai, Jinyang, Jacob, Sheeba, Kurupi, Richard, Dalton, Krista M., Coon, Colin, Greninger, Patricia, Egan, Regina K., Stein, Giovanna T., Murchie, Ellen, McClanaghan, Joseph, Adachi, Yuta, Hirade, Kentaro, Dozmorov, Mikhail, Glod, John, Boikos, Sosipatros A., Ebi, Hiromichi, Hao, Huaixiang, Caponigro, Giordano, Benes, Cyril H., Faber, Anthony C.
Publicado 2022

Genomic screening reveals ubiquitin-like modifier activating enzyme 1 as a potent and druggable target in c-MYC-high triple negative breast cancer models

por Jacob, Sheeba, Turner, Tia H, Cai, Jinyang, Floros, Konstantinos V, Yu, Ann K, Coon, Colin M, Khatri, Rishabh, Alzubi, Mohammad A, Jakubik, Charles T, Bouck, Ynes M, Puchalapalli, Madhavi, Shende, Mayuri, Dozmorov, Mikhail G, Boikos, Sosipatros A, Hu, Bin, Harrell, J Chuck, Benes, Cyril H, Koblinski, Jennifer E, Costa, Carlotta, Faber, Anthony C
Publicado 2022

Pharmacologic Inhibition of SHP2 Blocks Both PI3K and MEK Signaling in Low-epiregulin HNSCC via GAB1

por Kurupi, Richard, Floros, Konstantinos V., Jacob, Sheeba, Chawla, Ayesha T., Cai, Jinyang, Hu, Bin, Puchalapalli, Madhavi, Coon, Colin M., Khatri, Rishabh, Crowther, Giovanna Stein, Egan, Regina K., Murchie, Ellen, Greninger, Patricia, Dalton, Krista M., Ghotra, Maninderjit S., Boikos, Sosipatros A., Koblinski, Jennifer E., Harada, Hisashi, Sun, Yue, Morgan, Iain M., Basu, Devraj, Dozmorov, Mikhail G., Benes, Cyril H., Faber, Anthony C.
Publicado 2022