Sub-picomolar relaxin signalling by a pre-assembled RXFP1, AKAP79, AC2, β-arrestin 2, PDE4D3 complex

por Halls, Michelle L, Cooper, Dermot M F
Publicado 2010

An Improved Targeted cAMP Sensor to Study the Regulation of Adenylyl Cyclase 8 by Ca(2+) Entry through Voltage-Gated Channels

por Everett, Katy L., Cooper, Dermot M. F.
Publicado 2013

Structural and Functional Determinants of AC8 Trafficking, Targeting and Responsiveness in Lipid Raft Microdomains

por Tabbasum, Valentina G., Cooper, Dermot M. F.
Publicado 2019

Distinct Mechanisms of Calmodulin Binding and Regulation of Adenylyl Cyclases 1 and 8

por Masada, Nanako, Schaks, Sabine, Jackson, Sophie E., Sinz, Andrea, Cooper, Dermot M. F.
Publicado 2012

Separate Elements within a Single IQ-like Motif in Adenylyl Cyclase Type 8 Impart Ca(2+)/Calmodulin Binding and Autoinhibition

por MacDougall, David A., Wachten, Sebastian, Ciruela, Antonio, Sinz, Andrea, Cooper, Dermot M. F.
Publicado 2009

Muscarinic receptors stimulate AC2 by novel phosphorylation sites, whereas Gβγ subunits exert opposing effects depending on the G-protein source

por Shen, Jia X., Wachten, Sebastian, Halls, Michelle L., Everett, Katy L., Cooper, Dermot M. F.
Publicado 2012

Palmitoylation Targets AKAP79 Protein to Lipid Rafts and Promotes Its Regulation of Calcium-sensitive Adenylyl Cyclase Type 8

por Delint-Ramirez, Ilse, Willoughby, Debbie, Hammond, Gerald V. R., Ayling, Laura J., Cooper, Dermot M. F.
Publicado 2011

Dominant regulation of interendothelial cell gap formation by calcium-inhibited type 6 adenylyl cyclase

por Cioffi, Donna L., Moore, Timothy M., Schaack, Jerry, Creighton, Judy R., Cooper, Dermot M.F., Stevens, Troy
Publicado 2002

Cyclic Nucleotide–Gated Channels Colocalize with Adenylyl Cyclase in Regions of Restricted Camp Diffusion

por Rich, Thomas C., Fagan, Kent A., Nakata, Hiroko, Schaack, Jerome, Cooper, Dermot M.F., Karpen, Jeffrey W.
Publicado 2000

Insights into the residence in lipid rafts of adenylyl cyclase AC8 and its regulation by capacitative calcium entry

por Pagano, Mario, Clynes, Michael A., Masada, Nanako, Ciruela, Antonio, Ayling, Laura-Jo, Wachten, Sebastian, Cooper, Dermot M. F.
Publicado 2009

AKAP79/150 Interacts with AC8 and Regulates Ca(2+)-dependent cAMP Synthesis in Pancreatic and Neuronal Systems

por Willoughby, Debbie, Masada, Nanako, Wachten, Sebastian, Pagano, Mario, Halls, Michelle L., Everett, Katy L., Ciruela, Antonio, Cooper, Dermot M. F.
Publicado 2010

AKAP79 Orchestrates a Cyclic AMP Signalosome Adjacent to Orai1 Ca(2+) Channels

por Kar, Pulak, Barak, Pradeep, Zerio, Anna, Lin, Yu-Ping, Parekh, Amy J, Watts, Val J, Cooper, Dermot M F, Zaccolo, Manuela, Kramer, Holger, Parekh, Anant B
Publicado 2021

ADCY5 Couples Glucose to Insulin Secretion in Human Islets

por Hodson, David J., Mitchell, Ryan K., Marselli, Lorella, Pullen, Timothy J., Gimeno Brias, Silvia, Semplici, Francesca, Everett, Katy L., Cooper, Dermot M.F., Bugliani, Marco, Marchetti, Piero, Lavallard, Vanessa, Bosco, Domenico, Piemonti, Lorenzo, Johnson, Paul R., Hughes, Stephen J., Li, Daliang, Li, Wen-Hong, Shapiro, A.M. James, Rutter, Guy A.
Publicado 2014

Highly Functionalized Terpyridines as Competitive Inhibitors of AKAP–PKA Interactions**

por Schäfer, Gesa, Milić, Jelena, Eldahshan, Adeeb, Götz, Frank, Zühlke, Kerstin, Schillinger, Christian, Kreuchwig, Annika, Elkins, Jonathan M, Abdul Azeez, Kamal R, Oder, Andreas, Moutty, Marie C, Masada, Nanako, Beerbaum, Monika, Schlegel, Brigitte, Niquet, Sylvia, Schmieder, Peter, Krause, Gerd, von Kries, Jens Peter, Cooper, Dermot M F, Knapp, Stefan, Rademann, Jörg, Rosenthal, Walter, Klussmann, Enno
Publicado 2013

Small Molecule AKAP-Protein Kinase A (PKA) Interaction Disruptors That Activate PKA Interfere with Compartmentalized cAMP Signaling in Cardiac Myocytes

por Christian, Frank, Szaszák, Márta, Friedl, Sabine, Drewianka, Stephan, Lorenz, Dorothea, Goncalves, Andrey, Furkert, Jens, Vargas, Carolyn, Schmieder, Peter, Götz, Frank, Zühlke, Kerstin, Moutty, Marie, Göttert, Hendrikje, Joshi, Mangesh, Reif, Bernd, Haase, Hannelore, Morano, Ingo, Grossmann, Solveig, Klukovits, Anna, Verli, Judit, Gáspár, Róbert, Noack, Claudia, Bergmann, Martin, Kass, Robert, Hampel, Kornelia, Kashin, Dmitry, Genieser, Hans-Gottfried, Herberg, Friedrich W., Willoughby, Debbie, Cooper, Dermot M. F., Baillie, George S., Houslay, Miles D., von Kries, Jens Peter, Zimmermann, Bastian, Rosenthal, Walter, Klussmann, Enno
Publicado 2011