The structure of Toho1 β‐lactamase in complex with penicillin reveals the role of Tyr105 in substrate recognition

por Langan, Patricia S., Vandavasi, Venu Gopal, Weiss, Kevin L., Cooper, Jonathan B., Ginell, Stephan L., Coates, Leighton
Publicado 2016

Structure-based design and functional studies of novel noroviral 3C protease chimaeras offer insights into substrate specificity

por Herod, Morgan R., Prince, Cynthia A., Skilton, Rachel J., Ward, Vernon K., Cooper, Jonathan B., Clarke, Ian N.
Publicado 2014

Active-Site Protonation States in an Acyl-Enzyme Intermediate of a Class A β-Lactamase with a Monobactam Substrate

por Vandavasi, Venu Gopal, Langan, Patricia S., Weiss, Kevin L., Parks, Jerry M., Cooper, Jonathan B., Ginell, Stephan L., Coates, Leighton
Publicado 2016

Impact of Deuteration on the Assembly Kinetics of Transthyretin Monitored by Native Mass Spectrometry and Implications for Amyloidoses

por Yee, Ai Woon, Moulin, Martine, Breteau, Nina, Haertlein, Michael, Mitchell, Edward P., Cooper, Jonathan B., Boeri Erba, Elisabetta, Forsyth, V. Trevor
Publicado 2016

In crystallo-screening for discovery of human norovirus 3C-like protease inhibitors

por Guo, Jingxu, Douangamath, Alice, Song, Weixiao, Coker, Alun R., Chan, A.W. Edith, Wood, Steve P., Cooper, Jonathan B., Resnick, Efrat, London, Nir, Delft, Frank von
Publicado 2020

A Structural Study of Norovirus 3C Protease Specificity: Binding of a Designed Active Site-Directed Peptide Inhibitor

por Hussey, Robert J., Coates, Leighton, Gill, Raj S., Erskine, Peter T., Coker, Shu-Fen, Mitchell, Ed, Cooper, Jonathan B., Wood, Steve, Broadbridge, Robert, Clarke, Ian N., Lambden, Paul R., Shoolingin-Jordan, Peter M.
Publicado 2010