Top-down and bottom-up propagation of disease in the neuronal ceroid lipofuscinoses

por Ostergaard, John R., Nelvagal, Hemanth R., Cooper, Jonathan D.
Publicado 2022

Glial Dysfunction and Its Contribution to the Pathogenesis of the Neuronal Ceroid Lipofuscinoses

por Takahashi, Keigo, Nelvagal, Hemanth R., Lange, Jenny, Cooper, Jonathan D.
Publicado 2022

Anti-Inflammatory Impact of Minocycline in a Mouse Model of Tauopathy

por Garwood, Claire J., Cooper, Jonathan D., Hanger, Diane P., Noble, Wendy
Publicado 2010

Neurodegeneration and Epilepsy in a Zebrafish Model of CLN3 Disease (Batten Disease)

por Wager, Kim, Zdebik, Anselm A., Fu, Sonia, Cooper, Jonathan D., Harvey, Robert J., Russell, Claire
Publicado 2016

Early glial activation, synaptic changes and axonal pathology in the thalamocortical system of Niemann–Pick type C1 mice

por Pressey, Sarah N.R., Smith, David A., Wong, Andrew M.S., Platt, Frances M., Cooper, Jonathan D.
Publicado 2012

A Murine Model of Variant Late Infantile Ceroid Lipofuscinosis Recapitulates Behavioral and Pathological Phenotypes of Human Disease

por Morgan, Jeremy P., Magee, Helen, Wong, Andrew, Nelson, Tarah, Koch, Bettina, Cooper, Jonathan D., Weimer, Jill M.
Publicado 2013

Brain gene expression profiles of Cln1 and Cln5 deficient mice unravels common molecular pathways underlying neuronal degeneration in NCL diseases

por von Schantz, Carina, Saharinen, Juha, Kopra, Outi, Cooper, Jonathan D, Gentile, Massimiliano, Hovatta, Iiris, Peltonen, Leena, Jalanko, Anu
Publicado 2008

Correction: Disruption of the Autophagy-Lysosome Pathway Is Involved in Neuropathology of the nclf Mouse Model of Neuronal Ceroid Lipofuscinosis

por Thelen, Melanie, Damme, Markus, Schweizer, Michaela, Hagel, Christian, Wong, Andrew M.S., Cooper, Jonathan D., Braulke, Thomas, Galliciotti, Giovanna
Publicado 2012

Evolution of structural abnormalities in the rat brain following in utero exposure to maternal immune activation: A longitudinal in vivo MRI study

por Crum, William R., Sawiak, Stephen J., Chege, Winfred, Cooper, Jonathan D., Williams, Steven C.R., Vernon, Anthony C.
Publicado 2017

Compromised astrocyte function and survival negatively impact neurons in infantile neuronal ceroid lipofuscinosis

por Lange, Jenny, Haslett, Luke J., Lloyd-Evans, Emyr, Pocock, Jennifer M., Sands, Mark S., Williams, Brenda P., Cooper, Jonathan D.
Publicado 2018

Brain volume in chronic ketamine users — relationship to sub-threshold psychotic symptoms and relevance to schizophrenia

por Chesters, Robert A., Pepper, Fiona, Morgan, Celia, Cooper, Jonathan D., Howes, Oliver D., Vernon, Anthony C., Stone, James M.
Publicado 2021

Disruption of the Autophagy-Lysosome Pathway Is Involved in Neuropathology of the nclf Mouse Model of Neuronal Ceroid Lipofuscinosis

por Thelen, Melanie, Daμμe, Markus, Schweizer, Michaela, Hagel, Christian, Wong, Andrew M.S., Cooper, Jonathan D., Braulke, Thomas, Galliciotti, Giovanna
Publicado 2012

Genetically Corrected iPSC-Derived Neural Stem Cell Grafts Deliver Enzyme Replacement to Affect CNS Disease in Sanfilippo B Mice

por Clarke, Don, Pearse, Yewande, Kan, Shih-hsin, Le, Steven Q., Sanghez, Valentina, Cooper, Jonathan D., Dickson, Patricia I., Iacovino, Michelina
Publicado 2018

Exacerbated neuronal ceroid lipofuscinosis phenotype in Cln1/5 double-knockout mice

por Blom, Tea, Schmiedt, Mia-Lisa, Wong, Andrew M., Kyttälä, Aija, Soronen, Jarkko, Jauhiainen, Matti, Tyynelä, Jaana, Cooper, Jonathan D., Jalanko, Anu
Publicado 2013

Efficacy of phosphodiesterase‐4 inhibitors in juvenile Batten disease (CLN3)

por Aldrich, Amy, Bosch, Megan E., Fallet, Rachel, Odvody, Jessica, Burkovetskaya, Maria, Rama Rao, Kakulavarapu V., Cooper, Jonathan D., Drack, Arlene V., Kielian, Tammy
Publicado 2016

Proteomic mapping of differentially vulnerable pre-synaptic populations identifies regulators of neuronal stability in vivo

por Llavero Hurtado, Maica, Fuller, Heidi R., Wong, Andrew M. S., Eaton, Samantha L., Gillingwater, Thomas H., Pennetta, Giuseppa, Cooper, Jonathan D., Wishart, Thomas M.
Publicado 2017

Combined Anti-inflammatory and Neuroprotective Treatments Have the Potential to Impact Disease Phenotypes in Cln3(−/−) Mice

por Tarczyluk-Wells, Marta A., Salzlechner, Christoph, Najafi, Allison R., Lim, Ming J., Smith, David, Platt, Frances M., Williams, Brenda P., Cooper, Jonathan D.
Publicado 2019

Comparative proteomic profiling reveals mechanisms for early spinal cord vulnerability in CLN1 disease

por Nelvagal, Hemanth R., Hurtado, Maica Llavero, Eaton, Samantha L., Kline, Rachel A., Lamont, Douglas J., Sands, Mark S., Wishart, Thomas M., Cooper, Jonathan D.
Publicado 2020

Effects of chronic cannabidiol in a mouse model of naturally occurring neuroinflammation, neurodegeneration, and spontaneous seizures

por Dearborn, Joshua T., Nelvagal, Hemanth R., Rensing, Nicholas R., Takahashi, Keigo, Hughes, Stephanie M., Wishart, Thomas M., Cooper, Jonathan D., Wong, Michael, Sands, Mark S.
Publicado 2022

Trehalose reduces retinal degeneration, neuroinflammation and storage burden caused by a lysosomal hydrolase deficiency

por Lotfi, Parisa, Tse, Dennis Y., Di Ronza, Alberto, Seymour, Michelle L., Martano, Giuseppe, Cooper, Jonathan D., Pereira, Fred A., Passafaro, Maria, Wu, Samuel M., Sardiello, Marco
Publicado 2018