The human application of gene therapy to re-program T-cell specificity using chimeric antigen receptors

por Guerrero, Alan D, Moyes, Judy S, Cooper, Laurence JN
Publicado 2014

Clinical Applications of Gamma Delta T Cells with Multivalent Immunity

por Deniger, Drew C., Moyes, Judy S., Cooper, Laurence J. N.
Publicado 2014

Functional and molecular characterization of single serial killer CAR+ T cells demonstrates adaptive modification of behavior and fate based on tumor cell density

por Varadarajan, Navin, Liadi, Ivan, Romain, Gabrielle, Singh, Harjeet, Cooper, Laurence
Publicado 2014

Steering CAR T cells to distinguish friend from foe

por Caruso, Hillary G., Heimberger, Amy B., Cooper, Laurence J. N.
Publicado 2018

Cytotoxic T lymphocytes targeting a conserved SARS-CoV-2 spike epitope are efficient serial killers

por Fathi, Mohsen, Charley, Lindsey, Cooper, Laurence JN, Varadarajan, Navin, Meyer, Daniel D
Publicado 2022

Peripheral and Thymic Foxp3(+) Regulatory T Cells in Search of Origin, Distinction, and Function

por Dhamne, Chetan, Chung, Yeonseok, Alousi, Amin Majid, Cooper, Laurence J. N., Tran, Dat Quoc
Publicado 2013

Chimeric antigen receptor (CAR)+ T cell selection method affects transgene efficacy

por Rushworth, David, Mi, Tiejuan, Olivares, Simon, Carrero, Rosa Santana, Yang, Ge, Najjar, Amer, Cooper, Laurence
Publicado 2013

Single cell metrics of the efficacy of CAR T cells

por Romain, Gabrielle, Singh, Harjeet, Liadi, Ivan, Adolacion, Jay R, Roysam, Badrinath, Cooper, Laurence, Varadarajan, Navin
Publicado 2015

Chimeric Antigen Receptor (CAR)-Specific Monoclonal Antibody to Detect CD19-Specific T Cells in Clinical Trials

por Jena, Bipulendu, Maiti, Sourindra, Huls, Helen, Singh, Harjeet, Lee, Dean A., Champlin, Richard E., Cooper, Laurence J. N.
Publicado 2013

Quantitative single-cell characterization of CAR+ T cell effector functions

por Liadi, Ivan, Singh, Harjeet, Romain, Gabrielle, Rey-Villamizar, Nicolas, Merouane, Amin, Roysam, Badrinath, Cooper, Laurence J, Varadarajan, Navin
Publicado 2013

Human LAP(+)GARP(+)FOXP3(+) regulatory T cells attenuate xenogeneic graft versus host disease

por Wang, Huihui, Song, Hyo, Pham, Anha V., Cooper, Laurence J., Schulze, Janika J., Olek, Sven, Tran, Dat Q.
Publicado 2019

Feasibility and safety of cCD20 RNA CAR-bearing T cell therapy for the treatment of canine B cell malignancies

por Smith, Jenessa B, Panjwani, M Kazim, Schutsky, Keith, Gnanandarajah, Josephine, Calhoun, Sondra, Cooper, Laurence, Mason, Nicola, Powell, Daniel J
Publicado 2015

Very rapid cloning, expression and identifying specificity of T-cell receptors for T-cell engineering

por Zong, Shan, Mi, Tiejuan, Flores, Leo G., Alpert, Amir, Olivares, Simon, Patel, Krina, Maiti, Sourindra, Mcnamara, George, Cooper, Laurence J. N., Torikai, Hiroki
Publicado 2020

Bioengineering cytotoxic T cells to target opportunistic fungal infection

por Kumaresan, Pappanaicken, Manuri, Pallavi R, Albert, Nathaniel, Rabinovich, Brian, Olivares, Simon, Maiti, Sourindra N, Huls, Helen, Lee, Dean A, Kontoyiannis, Dimitrios, Cooper, Laurence J
Publicado 2013

Clinical Application of Sleeping Beauty and Artificial Antigen Presenting Cells to Genetically Modify T Cells from Peripheral and Umbilical Cord Blood

por Huls, M. Helen, Figliola, Matthew J., Dawson, Margaret J., Olivares, Simon, Kebriaei, Partow, Shpall, Elizabeth J., Champlin, Richard E., Singh, Harjeet, Cooper, Laurence J.N.
Publicado 2013

Regulated intratumoral expression of IL-12 using a RheoSwitch Therapeutic System(®) (RTS(®)) gene switch as gene therapy for the treatment of glioma

por Barrett, John A., Cai, Hongliang, Miao, John, Khare, Pranay D., Gonzalez, Paul, Dalsing-Hernandez, Jessica, Sharma, Geeta, Chan, Tim, Cooper, Laurence J.N, Lebel, Francois
Publicado 2018

The beneficial effects of a gas-permeable flask for expansion of Tumor-Infiltrating lymphocytes as reflected in their mitochondrial function and respiration capacity

por Forget, Marie-Andrée, Haymaker, Cara, Dennison, Jennifer B, Toth, Christopher, Maiti, Sourindra, Fulbright, Orenthial J, Cooper, Laurence J N, Hwu, Patrick, Radvanyi, Laszlo G, Bernatchez, Chantale
Publicado 2015

Tumor Lysing Genetically Engineered T Cells Loaded with Multi-Modal Imaging Agents

por Bhatnagar, Parijat, Alauddin, Mian, Bankson, James A., Kirui, Dickson, Seifi, Payam, Huls, Helen, Lee, Dean A., Babakhani, Aydin, Ferrari, Mauro, Li, King C., Cooper, Laurence J. N.
Publicado 2014

Genetically modified artificial antigen-presenting cells (aAPC) for expansion of melanoma tumor infiltrating lymphocytes with optimal properties for adoptive cell therapy

por Forget, Marie-Andrée, Malu, Shruti, Liu, Hiu, Toth, Christopher, Maiti, Sourindra, Kale, Charuta, Bernatchez, Chantale, Huls, Helen, Wang, Ena, Hwu, Patrick, Cooper, Laurence J, Radvanyi, Laszlo G
Publicado 2013

Redirecting Specificity of T cells Using the Sleeping Beauty System to Express Chimeric Antigen Receptors by Mix-and-Matching of V(L) and V(H) Domains Targeting CD123(+) Tumors

por Thokala, Radhika, Olivares, Simon, Mi, Tiejuan, Maiti, Sourindra, Deniger, Drew, Huls, Helen, Torikai, Hiroki, Singh, Harjeet, Champlin, Richard E., Laskowski, Tamara, McNamara, George, Cooper, Laurence J. N.
Publicado 2016