Senescent cells as a source of inflammatory factors for tumor progression

por Davalos, Albert R., Coppe, Jean-Philippe, Campisi, Judith, Desprez, Pierre-Yves
Publicado 2010

Response and resistance to BRAF(V600E) inhibition in gliomas: Roadblocks ahead?

por Capogiri, Monica, De Micheli, Andrea J., Lassaletta, Alvaro, Muñoz, Denise P., Coppé, Jean-Philippe, Mueller, Sabine, Guerreiro Stucklin, Ana S.
Publicado 2023

Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor

por Coppé, Jean-Philippe, Patil, Christopher K, Rodier, Francis, Sun, Yu, Muñoz, Denise P, Goldstein, Joshua, Nelson, Peter S, Desprez, Pierre-Yves, Campisi, Judith
Publicado 2008

p53-dependent release of Alarmin HMGB1 is a central mediator of senescent phenotypes

por Davalos, Albert R., Kawahara, Misako, Malhotra, Gautam K., Schaum, Nicholas, Huang, Jiahao, Ved, Urvi, Beausejour, Christian M., Coppe, Jean-Philippe, Rodier, Francis, Campisi, Judith
Publicado 2013

A Human-Like Senescence-Associated Secretory Phenotype Is Conserved in Mouse Cells Dependent on Physiological Oxygen

por Coppé, Jean-Philippe, Patil, Christopher K., Rodier, Francis, Krtolica, Ana, Beauséjour, Christian M., Parrinello, Simona, Hodgson, J. Graeme, Chin, Koei, Desprez, Pierre-Yves, Campisi, Judith
Publicado 2010

Persistent DNA damage signaling triggers senescence-associated inflammatory cytokine secretion

por Rodier, Francis, Coppé, Jean-Philippe, Patil, Christopher K., Hoeijmakers, Wieteke A. M., Muñoz, Denise P., Raza, Saba R., Freund, Adam, Campeau, Eric, Davalos, Albert R., Campisi, Judith
Publicado 2009

Targeting amphiregulin (AREG) derived from senescent stromal cells diminishes cancer resistance and averts programmed cell death 1 ligand (PD‐L1)‐mediated immunosuppression

por Xu, Qixia, Long, Qilai, Zhu, Dexiang, Fu, Da, Zhang, Boyi, Han, Liu, Qian, Min, Guo, Jianming, Xu, Jianmin, Cao, Liu, Chin, Y. Eugene, Coppé, Jean‐Philippe, Lam, Eric W.‐F., Campisi, Judith, Sun, Yu
Publicado 2019

Targeting SPINK1 in the damaged tumour microenvironment alleviates therapeutic resistance

por Chen, Fei, Long, Qilai, Fu, Da, Zhu, Dexiang, Ji, Yan, Han, Liu, Zhang, Boyi, Xu, Qixia, Liu, Bingjie, Li, Yan, Wu, Shanshan, Yang, Chen, Qian, Min, Xu, Jianmin, Liu, Suling, Cao, Liu, Chin, Y. Eugene, Lam, Eric W.-F., Coppé, Jean-Philippe, Sun, Yu
Publicado 2018

B-cells and regulatory T-cells in the microenvironment of HER2+ breast cancer are associated with decreased survival: a real-world analysis of women with HER2+ metastatic breast ca...

por Steenbruggen, Tessa G., Wolf, Denise M., Campbell, Michael J., Sanders, Joyce, Cornelissen, Sten, Thijssen, Bram, Salgado, Roberto A., Yau, Christina, O-Grady, Nick, Basu, Amrita, Bhaskaran, Rajith, Mittempergher, Lorenza, Hirst, Gillian L., Coppe, Jean-Philippe, Kok, Marleen, Sonke, Gabe S., van ‘t Veer, Laura J., Horlings, Hugo M.
Publicado 2023

Hyperphosphorylation of BCL-2 family proteins underlies functional resistance to venetoclax in lymphoid malignancies

por Chong, Stephen Jun Fei, Zhu, Fen, Dashevsky, Olga, Mizuno, Rin, Lai, Jolin X.H., Hackett, Liam, Ryan, Christine E., Collins, Mary C., Iorgulescu, J. Bryan, Guièze, Romain, Penailillo, Johany, Carrasco, Ruben, Hwang, Yeonjoo C., Muñoz, Denise P., Bouhaddou, Mehdi, Lim, Yaw Chyn, Wu, Catherine J., Allan, John N., Furman, Richard R., Goh, Boon Cher, Pervaiz, Shazib, Coppé, Jean-Philippe, Mitsiades, Constantine S., Davids, Matthew S.
Publicado 2023

A reversible SRC-relayed COX2 inflammatory program drives resistance to BRAF and EGFR inhibition in BRAF(V600E) colorectal tumors

por Ruiz-Saenz, Ana, Atreya, Chloe E., Wang, Changjun, Pan, Bo, Dreyer, Courtney A., Brunen, Diede, Prahallad, Anirudh, Muñoz, Denise P., Ramms, Dana J., Burghi, Valeria, Spassov, Danislav S., Fewings, Eleanor, Hwang, Yeonjoo C., Cowdrey, Cynthia, Moelders, Christina, Schwarzer, Cecilia, Wolf, Denise M., Hann, Byron, VandenBerg, Scott R., Shokat, Kevan, Moasser, Mark M., Bernards, René, Gutkind, J. Silvio, van ‘t Veer, Laura J., Coppé, Jean-Philippe
Publicado 2023

Heterogeneous drug penetrance of veliparib and carboplatin measured in triple negative breast tumors

por Bartelink, Imke H., Prideaux, Brendan, Krings, Gregor, Wilmes, Lisa, Lee, Pei Rong Evelyn, Bo, Pan, Hann, Byron, Coppé, Jean-Philippe, Heditsian, Diane, Swigart-Brown, Lamorna, Jones, Ella F., Magnitsky, Sergey, Keizer, Ron J, de Vries, Niels, Rosing, Hilde, Pawlowska, Nela, Thomas, Scott, Dhawan, Mallika, Aggarwal, Rahul, Munster, Pamela N., Esserman, Laura J., Ruan, Weiming, Wu, Alan H. B., Yee, Douglas, Dartois, Véronique, Savic, Radojka M., Wolf, Denise M., van ’t Veer, Laura
Publicado 2017