Using inactivating mutations to provide insight into drug action

por Corbin, Laura J, Timpson, Nicholas J
Publicado 2015

Genetics, sleep and memory: a recall-by-genotype study of ZNF804A variants and sleep neurophysiology

por Hellmich, Charlotte, Durant, Claire, Jones, Matthew W., Timpson, Nicholas J., Bartsch, Ullrich, Corbin, Laura J.
Publicado 2015

An Independent Locus Upstream of ASIP Controls Variation in the Shade of the Bay Coat Colour in Horses

por Corbin, Laura J., Pope, Jessica, Sanson, Jacqueline, Antczak, Douglas F., Miller, Donald, Sadeghi, Raheleh, Brooks, Samantha A.
Publicado 2020

Evaluating the association of TRPA1 gene polymorphisms with pain sensitivity: a protocol for an adaptive recall by genotype study

por Nickerson, Aidan P., Corbin, Laura J., Timpson, Nicholas J., Phillips, Keith, Pickering, Anthony E., Dunham, James P.
Publicado 2022

A multivariant recall‐by‐genotype study of the metabolomic signature of BMI

por Fang, Si, Wade, Kaitlin H., Hughes, David A., Fitzgibbon, Sophie, Yip, Vikki, Timpson, Nicholas J., Corbin, Laura J.
Publicado 2022

The utility of low-density genotyping for imputation in the Thoroughbred horse

por Corbin, Laura J, Kranis, Andreas, Blott, Sarah C, Swinburne, June E, Vaudin, Mark, Bishop, Stephen C, Woolliams, John A
Publicado 2014

metaboprep: an R package for preanalysis data description and processing

por Hughes, David A, Taylor, Kurt, McBride, Nancy, Lee, Matthew A, Mason, Dan, Lawlor, Deborah A, Timpson, Nicholas J, Corbin, Laura J
Publicado 2022

Schizophrenia-associated variation at ZNF804A correlates with altered experience-dependent dynamics of sleep slow waves and spindles in healthy young adults

por Bartsch, Ullrich, Corbin, Laura J, Hellmich, Charlotte, Taylor, Michelle, Easey, Kayleigh E, Durant, Claire, Marston, Hugh M, Timpson, Nicholas J, Jones, Matthew W
Publicado 2021

Metabolic characterisation of disturbances in the APOC3/triglyceride-rich lipoprotein pathway through sample-based recall by genotype

por Corbin, Laura J., Hughes, David A., Chetwynd, Andrew J., Taylor, Amy E., Southam, Andrew D., Jankevics, Andris, Weber, Ralf J. M., Groom, Alix, Dunn, Warwick B., Timpson, Nicholas J.
Publicado 2020

Common variation at 16p11.2 is associated with glycosuria in pregnancy: findings from a genome-wide association study in European women

por Lee, Matthew A, McMahon, George, Karhunen, Ville, Wade, Kaitlin H, Corbin, Laura J, Hughes, David A, Smith, George Davey, Lawlor, Debbie A, Jarvelin, Marjo-Riitta, Timpson, Nicholas J
Publicado 2020

Genetic architecture of human thinness compared to severe obesity

por Riveros-McKay, Fernando, Mistry, Vanisha, Bounds, Rebecca, Hendricks, Audrey, Keogh, Julia M., Thomas, Hannah, Henning, Elana, Corbin, Laura J., O’Rahilly, Stephen, Zeggini, Eleftheria, Wheeler, Eleanor, Barroso, Inês, Farooqi, I. Sadaf
Publicado 2019

Using trials of caloric restriction and bariatric surgery to explore the effects of body mass index on the circulating proteome

por Goudswaard, Lucy J., Smith, Madeleine L., Hughes, David A., Taylor, Roy, Lean, Michael, Sattar, Naveed, Welsh, Paul, McConnachie, Alex, Blazeby, Jane M., Rogers, Chris A., Suhre, Karsten, Zaghlool, Shaza B., Hers, Ingeborg, Timpson, Nicholas J., Corbin, Laura J.
Publicado 2023

Effects of adiposity on the human plasma proteome: observational and Mendelian randomisation estimates

por Goudswaard, Lucy J., Bell, Joshua A., Hughes, David A., Corbin, Laura J., Walter, Klaudia, Davey Smith, George, Soranzo, Nicole, Danesh, John, Di Angelantonio, Emanuele, Ouwehand, Willem H., Watkins, Nicholas A., Roberts, David J., Butterworth, Adam S., Hers, Ingeborg, Timpson, Nicholas J.
Publicado 2021

Investigation of the Interplay between Circulating Lipids and IGF-I and Relevance to Breast Cancer Risk: An Observational and Mendelian Randomization Study

por Tan, Vanessa Y., Bull, Caroline J., Biernacka, Kalina M., Teumer, Alexander, Richardson, Tom G., Sanderson, Eleanor, Corbin, Laura J., Dudding, Tom, Qi, Qibin, Kaplan, Robert C., Rotter, Jerome I., Friedrich, Nele, Völker, Uwe, Mayerle, Julia, Perks, Claire M., Holly, Jeff M.P., Timpson, Nicholas J.
Publicado 2021

Loss of function mutations in the melanocortin 4 receptor in a UK birth cohort

por Wade, Kaitlin H, Lam, Brian YH, Melvin, Audrey, Pan, Warren, Corbin, Laura J, Hughes, David A, Rainbow, Kara, Chen, Jian-Hua, Duckett, Katie, Liu, Xiaoming, Mokrosiński, Jacek, Mörseburg, Alexander, Neaves, Sam, Williamson, Alice, Zhang, Chen, Farooqi, I. Sadaf, Yeo, Giles SH, Timpson, Nicholas J, O’Rahilly, Stephen
Publicado 2021

The Role of Inflammatory Cytokines as Intermediates in the Pathway from Increased Adiposity to Disease

por Kalaoja, Marita, Corbin, Laura J., Tan, Vanessa Y., Ahola‐Olli, Ari V., Havulinna, Aki S., Santalahti, Kristiina, Pitkänen, Niina, Lehtimäki, Terho, Lyytikäinen, Leo‐Pekka, Raitoharju, Emma, Seppälä, Ilkka, Kähönen, Mika, Ripatti, Samuli, Palotie, Aarno, Perola, Markus, Viikari, Jorma S., Jalkanen, Sirpa, Maksimow, Mikael, Salomaa, Veikko, Salmi, Marko, Raitakari, Olli T., Kettunen, Johannes, Timpson, Nicholas J.
Publicado 2021

Epigenetic Regulation of F2RL3 Associates With Myocardial Infarction and Platelet Function

por Corbin, Laura J., White, Stephen J., Taylor, Amy E., Williams, Christopher M., Taylor, Kurt, van den Bosch, Marion T., Teasdale, Jack E., Jones, Matthew, Bond, Mark, Harper, Matthew T., Falk, Louise, Groom, Alix, Hazell, Georgina G.J., Paternoster, Lavinia, Munafò, Marcus R., Nordestgaard, Børge G., Tybjærg-Hansen, Anne, Bojesen, Stig E., Relton, Caroline, Min, Josine L., Davey Smith, George, Mumford, Andrew D., Poole, Alastair W., Timpson, Nicholas J.
Publicado 2022

Formalising recall by genotype as an efficient approach to detailed phenotyping and causal inference

por Corbin, Laura J., Tan, Vanessa Y., Hughes, David A., Wade, Kaitlin H., Paul, Dirk S., Tansey, Katherine E., Butcher, Frances, Dudbridge, Frank, Howson, Joanna M., Jallow, Momodou W., John, Catherine, Kingston, Nathalie, Lindgren, Cecilia M., O’Donavan, Michael, O’Rahilly, Stephen, Owen, Michael J., Palmer, Colin N. A., Pearson, Ewan R., Scott, Robert A., van Heel, David A., Whittaker, John, Frayling, Tim, Tobin, Martin D., Wain, Louise V., Smith, George Davey, Evans, David M., Karpe, Fredrik, McCarthy, Mark I., Danesh, John, Franks, Paul W., Timpson, Nicholas J.
Publicado 2018

Prevalence of Deleterious Variants in MC3R in Patients With Constitutional Delay of Growth and Puberty

por Duckett, Katie, Williamson, Alice, Kincaid, John W R, Rainbow, Kara, Corbin, Laura J, Martin, Hilary C, Eberhardt, Ruth Y, Huang, Qin Qin, Hurles, Matthew E, He, Wen, Brauner, Raja, Delaney, Angela, Dunkel, Leo, Grinspon, Romina P, Hall, Janet E, Hirschhorn, Joel N, Howard, Sasha R, Latronico, Ana C, Jorge, Alexander A L, McElreavey, Ken, Mericq, Verónica, Merino, Paulina M, Palmert, Mark R, Plummer, Lacey, Rey, Rodolfo A, Rezende, Raíssa C, Seminara, Stephanie B, Salnikov, Kathryn, Banerjee, Indraneel, Lam, Brian Y H, Perry, John R B, Timpson, Nicholas J, Clayton, Peter, Chan, Yee-Ming, Ong, Ken K, O’Rahilly, Stephen
Publicado 2023

The blood metabolome of incident kidney cancer: A case–control study nested within the MetKid consortium

por Guida, Florence, Tan, Vanessa Y., Corbin, Laura J., Smith-Byrne, Karl, Alcala, Karine, Langenberg, Claudia, Stewart, Isobel D., Butterworth, Adam S., Surendran, Praveen, Achaintre, David, Adamski, Jerzy, Amiano, Pilar, Bergmann, Manuela M., Bull, Caroline J., Dahm, Christina C., Gicquiau, Audrey, Giles, Graham G., Gunter, Marc J., Haller, Toomas, Langhammer, Arnulf, Larose, Tricia L., Ljungberg, Börje, Metspalu, Andres, Milne, Roger L., Muller, David C., Nøst, Therese H., Pettersen Sørgjerd, Elin, Prehn, Cornelia, Riboli, Elio, Rinaldi, Sabina, Rothwell, Joseph A., Scalbert, Augustin, Schmidt, Julie A., Severi, Gianluca, Sieri, Sabina, Vermeulen, Roel, Vincent, Emma E., Waldenberger, Melanie, Timpson, Nicholas J., Johansson, Mattias
Publicado 2021