Dynamic 3D Locus Organization and Its Drivers Underpin Immunoglobulin Recombination

por Rogers, Carolyn H., Mielczarek, Olga, Corcoran, Anne E.
Publicado 2021

Robust 3D DNA FISH Using Directly Labeled Probes

por Bolland, Daniel J., King, Michelle R., Reik, Wolf, Corcoran, Anne E., Krueger, Christel
Publicado 2013

Local Chromatin Features Including PU.1 and IKAROS Binding and H3K4 Methylation Shape the Repertoire of Immunoglobulin Kappa Genes Chosen for V(D)J Recombination

por Matheson, Louise S., Bolland, Daniel J., Chovanec, Peter, Krueger, Felix, Andrews, Simon, Koohy, Hashem, Corcoran, Anne E.
Publicado 2017

ATMIN Is Required for Maintenance of Genomic Stability and Suppression of B Cell Lymphoma

por Loizou, Joanna I., Sancho, Rocio, Kanu, Nnennaya, Bolland, Daniel J., Yang, Fengtang, Rada, Cristina, Corcoran, Anne E., Behrens, Axel
Publicado 2011

IL-7R signaling activates widespread V(H) and D(H) gene usage to drive antibody diversity in bone marrow B cells

por Baizan-Edge, Amanda, Stubbs, Bryony A., Stubbington, Michael J.T., Bolland, Daniel J., Tabbada, Kristina, Andrews, Simon, Corcoran, Anne E.
Publicado 2021

Myc Dynamically and Preferentially Relocates to a Transcription Factory Occupied by Igh

por Osborne, Cameron S, Chakalova, Lyubomira, Mitchell, Jennifer A, Horton, Alice, Wood, Andrew L, Bolland, Daniel J, Corcoran, Anne E, Fraser, Peter
Publicado 2007

Widespread reorganisation of pluripotent factor binding and gene regulatory interactions between human pluripotent states

por Chovanec, Peter, Collier, Amanda J., Krueger, Christel, Várnai, Csilla, Semprich, Claudia I., Schoenfelder, Stefan, Corcoran, Anne E., Rugg-Gunn, Peter J.
Publicado 2021

Clonally stable Vκ allelic choice instructs Igκ repertoire

por Levin-Klein, Rena, Fraenkel, Shira, Lichtenstein, Michal, Matheson, Louise S., Bartok, Osnat, Nevo, Yuval, Kadener, Sebastian, Corcoran, Anne E., Cedar, Howard, Bergman, Yehudit
Publicado 2017

Shared Ageing Research Models (ShARM): a new facility to support ageing research

por Duran, Adele L., Potter, Paul, Wells, Sara, Kirkwood, Tom, von Zglinicki, Thomas, McArdle, Anne, Scudamore, Cheryl, Meng, Qing-Jun, de Haan, Gerald, Corcoran, Anne, Bellantuono, Ilaria
Publicado 2013

Comprehensive Cell Surface Protein Profiling Identifies Specific Markers of Human Naive and Primed Pluripotent States

por Collier, Amanda J., Panula, Sarita P., Schell, John Paul, Chovanec, Peter, Plaza Reyes, Alvaro, Petropoulos, Sophie, Corcoran, Anne E., Walker, Rachael, Douagi, Iyadh, Lanner, Fredrik, Rugg-Gunn, Peter J.
Publicado 2017

Two Mutually Exclusive Local Chromatin States Drive Efficient V(D)J Recombination

por Bolland, Daniel J., Koohy, Hashem, Wood, Andrew L., Matheson, Louise S., Krueger, Felix, Stubbington, Michael J.T., Baizan-Edge, Amanda, Chovanec, Peter, Stubbs, Bryony A., Tabbada, Kristina, Andrews, Simon R., Spivakov, Mikhail, Corcoran, Anne E.
Publicado 2016

The murine IgH locus contains a distinct DNA sequence motif for the chromatin regulatory factor CTCF

por Ciccone, David N., Namiki, Yuka, Chen, Changfeng, Morshead, Katrina B., Wood, Andrew L., Johnston, Colette M., Morris, John W., Wang, Yanqun, Sadreyev, Ruslan, Corcoran, Anne E., Matthews, Adam G. W., Oettinger, Marjorie A.
Publicado 2019

Heavy chain–only antibodies are spontaneously produced in light chain–deficient mice

por Zou, Xiangang, Osborn, Michael J., Bolland, Daniel J., Smith, Jennifer A., Corcos, Daniel, Hamon, Maureen, Oxley, David, Hutchings, Amanda, Morgan, Geoff, Santos, Fatima, Kilshaw, Peter J., Taussig, Michael J., Corcoran, Anne E., Brüggemann, Marianne
Publicado 2007

RUNX Transcription Factor-Mediated Association of Cd4 and Cd8 Enables Coordinate Gene Regulation

por Collins, Amélie, Hewitt, Susannah L., Chaumeil, Julie, Sellars, MacLean, Micsinai, Mariann, Allinne, Jeanne, Parisi, Fabio, Nora, Elphège P., Bolland, Dan J., Corcoran, Anne E., Kluger, Yuval, Bosselut, Remy, Ellmeier, Wilfried, Chong, Mark M.W., Littman, Dan R., Skok, Jane A.
Publicado 2011

Intra- and interchromosomal contact mapping reveals the Igh locus has extensive conformational heterogeneity and interacts with B-lineage genes

por Mielczarek, Olga, Rogers, Carolyn H., Zhan, Yinxiu, Matheson, Louise S., Stubbington, Michael J.T., Schoenfelder, Stefan, Bolland, Daniel J., Javierre, Biola M., Wingett, Steven W., Várnai, Csilla, Segonds-Pichon, Anne, Conn, Simon J., Krueger, Felix, Andrews, Simon, Fraser, Peter, Giorgetti, Luca, Corcoran, Anne E.
Publicado 2023

The adjuvant GLA-SE promotes human Tfh cell expansion and emergence of public TCRβ clonotypes

por Hill, Danika L., Pierson, Wim, Bolland, Daniel J., Mkindi, Catherine, Carr, Edward J., Wang, Jiong, Houard, Sophie, Wingett, Steven W., Audran, Regine, Wallin, Elizabeth F., Jongo, Said A., Kamaka, Kassim, Zand, Martin, Spertini, Francois, Daubenberger, Claudia, Corcoran, Anne E., Linterman, Michelle A.
Publicado 2019

Genome organization and chromatin analysis identify transcriptional downregulation of insulin-like growth factor signaling as a hallmark of aging in developing B cells

por Koohy, Hashem, Bolland, Daniel J., Matheson, Louise S., Schoenfelder, Stefan, Stellato, Claudia, Dimond, Andrew, Várnai, Csilla, Chovanec, Peter, Chessa, Tamara, Denizot, Jeremy, Manzano Garcia, Raquel, Wingett, Steven W., Freire-Pritchett, Paula, Nagano, Takashi, Hawkins, Phillip, Stephens, Len, Elderkin, Sarah, Spivakov, Mikhail, Fraser, Peter, Corcoran, Anne E., Varga-Weisz, Patrick D.
Publicado 2018

Epigenomic translocation of H3K4me3 broad domains over oncogenes following hijacking of super-enhancers

por Mikulasova, Aneta, Kent, Daniel, Trevisan-Herraz, Marco, Karataraki, Nefeli, Fung, Kent T.M., Ashby, Cody, Cieslak, Agata, Yaccoby, Shmuel, van Rhee, Frits, Zangari, Maurizio, Thanendrarajan, Sharmilan, Schinke, Carolina, Morgan, Gareth J., Asnafi, Vahid, Spicuglia, Salvatore, Brackley, Chris A., Corcoran, Anne E., Hambleton, Sophie, Walker, Brian A., Rico, Daniel, Russell, Lisa J.
Publicado 2022