Itaconate Alters Succinate and Coenzyme A Metabolism via Inhibition of Mitochondrial Complex II and Methylmalonyl-CoA Mutase

por Cordes, Thekla, Metallo, Christian M.
Publicado 2021

Mapping the Metabolic Niche of Citrate Metabolism and SLC13A5

por Chen, Fangfang, Willenbockel, Hanna Friederike, Cordes, Thekla
Publicado 2023

A biomolecular isolation framework for eco-systems biology

por Roume, Hugo, EL Muller, Emilie, Cordes, Thekla, Renaut, Jenny, Hiller, Karsten, Wilmes, Paul
Publicado 2013

The Virulence Factor Macrophage Infectivity Potentiator (Mip) Influences Branched-Chain Amino Acid Metabolism and Pathogenicity of Legionella pneumophila

por Nikolka, Fabian, Karagöz, Mustafa Safa, Nassef, Mohamed Zakaria, Hiller, Karsten, Steinert, Michael, Cordes, Thekla
Publicado 2023

Itaconate modulates tricarboxylic acid and redox metabolism to mitigate reperfusion injury

por Cordes, Thekla, Lucas, Alfredo, Divakaruni, Ajit S., Murphy, Anne N., Cabrales, Pedro, Metallo, Christian M.
Publicado 2019

Bridging the gap between non-targeted stable isotope labeling and metabolic flux analysis

por Weindl, Daniel, Cordes, Thekla, Battello, Nadia, Sapcariu, Sean C., Dong, Xiangyi, Wegner, Andre, Hiller, Karsten
Publicado 2016

NTFD—a stand-alone application for the non-targeted detection of stable isotope-labeled compounds in GC/MS data

por Hiller, Karsten, Wegner, André, Weindl, Daniel, Cordes, Thekla, Metallo, Christian M., Kelleher, Joanne K., Stephanopoulos, Gregory
Publicado 2013

NaCT/SLC13A5 facilitates citrate import and metabolism under nutrient-limited conditions

por Kumar, Avi, Cordes, Thekla, Thalacker-Mercer, Anna E., Pajor, Ana M., Murphy, Anne N., Metallo, Christian M.
Publicado 2021

1-Deoxysphingolipid synthesis compromises anchorage-independent growth and plasma membrane endocytosis in cancer cells

por Cordes, Thekla, Kuna, Ramya S., McGregor, Grace H., Khare, Sanika V., Gengatharan, Jivani, Muthusamy, Thangaselvam, Metallo, Christian M.
Publicado 2022

Charting oncogenicity of genes and variants across lineages via multiplexed screens in teratomas

por Parekh, Udit, McDonald, Daniella, Dailamy, Amir, Wu, Yan, Cordes, Thekla, Zhang, Kun, Tipps, Ann, Metallo, Christian, Mali, Prashant
Publicado 2021

Preserved cardiac function by vinculin enhances glucose oxidation and extends health- and life-span

por Sessions, Ayla O., Min, Peter, Cordes, Thekla, Weickert, Barry J., Divakaruni, Ajit S., Murphy, Anne N., Metallo, Christian M., Engler, Adam J.
Publicado 2018

Oncogenic R132 IDH1 Mutations Limit NADPH for De Novo Lipogenesis through (D)2-Hydroxyglutarate Production in Fibrosarcoma Cells

por Badur, Mehmet G., Muthusamy, Thangaselvam, Parker, Seth J., Ma, Shenghong, McBrayer, Samuel K., Cordes, Thekla, Magana, Jose H., Guan, Kun-Liang, Metallo, Christian M.
Publicado 2018

Oncogenic R132 IDH1 Mutations Limit NADPH for De Novo Lipogenesis through (D)2-Hydroxyglutarate Production in Fibrosarcoma Cells

por Badur, Mehmet G., Muthusamy, Thangaselvam, Parker, Seth J., Ma, Shenghong, McBrayer, Samuel K., Cordes, Thekla, Magana, Jose H., Guan, Kun-Liang, Metallo, Christian M.
Publicado 2018

Inter-organelle cross-talk supports acetyl-coenzyme A homeostasis and lipogenesis under metabolic stress

por Kuna, Ramya S., Kumar, Avi, Wessendorf-Rodriguez, Karl A., Galvez, Hector, Green, Courtney R., McGregor, Grace H., Cordes, Thekla, Shaw, Reuben J., Svensson, Robert U., Metallo, Christian M.
Publicado 2023

Stable Isotope-Assisted Untargeted Metabolomics Identifies ALDH1A1-Driven Erythronate Accumulation in Lung Cancer Cells

por Zhang, Jie, Keibler, Mark A., Dong, Wentao, Ghelfi, Jenny, Cordes, Thekla, Kanashova, Tamara, Pailot, Arnaud, Linster, Carole L., Dittmar, Gunnar, Metallo, Christian M., Lautenschlaeger, Tim, Hiller, Karsten, Stephanopoulos, Gregory
Publicado 2023

Serine restriction alters sphingolipid diversity to constrain tumor growth

por Muthusamy, Thangaselvam, Cordes, Thekla, Handzlik, Michal K., You, Le, Lim, Esther W., Gengatharan, Jivani, Pinto, Antonio F. M., Badur, Mehmet G., Kolar, Matthew J., Wallace, Martina, Saghatelian, Alan, Metallo, Christian M.
Publicado 2020

Inhibition of the mitochondrial pyruvate carrier protects from excitotoxic neuronal death

por Divakaruni, Ajit S., Wallace, Martina, Buren, Caodu, Martyniuk, Kelly, Andreyev, Alexander Y., Li, Edward, Fields, Jerel A., Cordes, Thekla, Reynolds, Ian J., Bloodgood, Brenda L., Raymond, Lynn A., Metallo, Christian M., Murphy, Anne N.
Publicado 2017

The lactate-NAD(+) axis activates cancer-associated fibroblasts by downregulating p62

por Linares, Juan F., Cid-Diaz, Tania, Duran, Angeles, Osrodek, Marta, Martinez-Ordoñez, Anxo, Reina-Campos, Miguel, Kuo, Hui-Hsuan, Elemento, Olivier, Martin, M. Laura, Cordes, Thekla, Thompson, Timothy C., Metallo, Christian M., Moscat, Jorge, Diaz-Meco, Maria T.
Publicado 2022