Blood phenylalanine reduction reverses gene expression changes observed in a mouse model of phenylketonuria

por Manek, Rachna, Zhang, Yao V., Berthelette, Patricia, Hossain, Mahmud, Cornell, Cathleen S., Gans, Joseph, Anarat-Cappillino, Gulbenk, Geller, Sarah, Jackson, Robert, Yu, Dan, Singh, Kuldeep, Ryan, Sue, Bangari, Dinesh S., Xu, Ethan Y., Kyostio-Moore, Sirkka R. M.
Publicado 2021

CRISPR/Cas9 generated knockout mice lacking phenylalanine hydroxylase protein as a novel preclinical model for human phenylketonuria

por Singh, Kuldeep, Cornell, Cathleen S., Jackson, Robert, Kabiri, Mostafa, Phipps, Michael, Desai, Mitul, Fogle, Robert, Ying, Xiaoyou, Anarat-Cappillino, Gulbenk, Geller, Sarah, Johnson, Jennifer, Roberts, Errin, Malley, Katie, Devlin, Tim, DeRiso, Matthew, Berthelette, Patricia, Zhang, Yao V., Ryan, Susan, Rao, Srinivas, Thurberg, Beth L., Bangari, Dinesh S., Kyostio-Moore, Sirkka
Publicado 2021