Different genetic requirements for repair of replication-born double-strand breaks by sister-chromatid recombination and break-induced replication

por Cortés-Ledesma, Felipe, Tous, Cristina, Aguilera, Andrés
Publicado 2007

“An End to a Means”: How DNA-End Structure Shapes the Double-Strand Break Repair Process

por Serrano-Benítez, Almudena, Cortés-Ledesma, Felipe, Ruiz, Jose F.
Publicado 2020

TDP2/TTRAP Is the Major 5′-Tyrosyl DNA Phosphodiesterase Activity in Vertebrate Cells and Is Critical for Cellular Resistance to Topoisomerase II-induced DNA Damage

por Zeng, Zhihong, Cortés-Ledesma, Felipe, El Khamisy, Sherif F., Caldecott, Keith W.
Publicado 2011

Competing roles of DNA end resection and non-homologous end joining functions in the repair of replication-born double-strand breaks by sister-chromatid recombination

por Muñoz-Galván, Sandra, López-Saavedra, Ana, Jackson, Stephen P., Huertas, Pablo, Cortés-Ledesma, Felipe, Aguilera, Andrés
Publicado 2013

Divergent Requirement for a DNA Repair Enzyme during Enterovirus Infections

por Maciejewski, Sonia, Nguyen, Joseph H. C., Gómez-Herreros, Fernando, Cortés-Ledesma, Felipe, Caldecott, Keith W., Semler, Bert L.
Publicado 2015

ATM specifically mediates repair of double-strand breaks with blocked DNA ends

por Álvarez-Quilón, Alejandro, Serrano-Benítez, Almudena, Ariel Lieberman, Jenna, Quintero, Cristina, Sánchez-Gutiérrez, Daniel, Escudero, Luis M., Cortés-Ledesma, Felipe
Publicado 2014

Genome-wide prediction of topoisomerase IIβ binding by architectural factors and chromatin accessibility

por Martínez-García, Pedro Manuel, García-Torres, Miguel, Divina, Federico, Terrón-Bautista, José, Delgado-Sainz, Irene, Gómez-Vela, Francisco, Cortés-Ledesma, Felipe
Publicado 2021

Topoisomerase IIα represses transcription by enforcing promoter-proximal pausing

por Herrero-Ruiz, Andrés, Martínez-García, Pedro Manuel, Terrón-Bautista, José, Millán-Zambrano, Gonzalo, Lieberman, Jenna Ariel, Jimeno-González, Silvia, Cortés-Ledesma, Felipe
Publicado 2021

Data of transcriptional effects of the merbarone-mediated inhibition of TOP2

por Delgado-Chaves, Fernando M., Martínez-García, Pedro Manuel, Herrero-Ruiz, Andrés, Gómez-Vela, Francisco, Divina, Federico, Jimeno-González, Silvia, Cortés-Ledesma, Felipe
Publicado 2022

Non-redundant Functions of ATM and DNA-PKcs in Response to DNA Double-Strand Breaks

por Caron, Pierre, Choudjaye, Jonathan, Clouaire, Thomas, Bugler, Béatrix, Daburon, Virginie, Aguirrebengoa, Marion, Mangeat, Thomas, Iacovoni, Jason S., Álvarez-Quilón, Alejandro, Cortés-Ledesma, Felipe, Legube, Gaëlle
Publicado 2015

TDP2–Dependent Non-Homologous End-Joining Protects against Topoisomerase II–Induced DNA Breaks and Genome Instability in Cells and In Vivo

por Gómez-Herreros, Fernando, Romero-Granados, Rocío, Zeng, Zhihong, Álvarez-Quilón, Alejandro, Quintero, Cristina, Ju, Limei, Umans, Lieve, Vermeire, Liesbeth, Huylebroeck, Danny, Caldecott, Keith W., Cortés-Ledesma, Felipe
Publicado 2013

TDP2 suppresses genomic instability induced by androgens in the epithelial cells of prostate glands

por Al Mahmud, Md. Rasel, Ishii, Kenichiro, Bernal‐Lozano, Cristina, Delgado‐Sainz, Irene, Toi, Masakazu, Akamatsu, Shusuke, Fukumoto, Manabu, Watanabe, Masatoshi, Takeda, Shunichi, Cortés‐Ledesma, Felipe, Sasanuma, Hiroyuki
Publicado 2020

Endogenous topoisomerase II-mediated DNA breaks drive thymic cancer predisposition linked to ATM deficiency

por Álvarez-Quilón, Alejandro, Terrón-Bautista, José, Delgado-Sainz, Irene, Serrano-Benítez, Almudena, Romero-Granados, Rocío, Martínez-García, Pedro Manuel, Jimeno-González, Silvia, Bernal-Lozano, Cristina, Quintero, Cristina, García-Quintanilla, Lourdes, Cortés-Ledesma, Felipe
Publicado 2020

The insecticides permethrin and chlorpyrifos show limited genotoxicity and no leukemogenic potential in human and murine hematopoietic stem progenitor cells

por Rodriguez-Cortez, Virginia C., Navarrete-Meneses, María Pilar, Molina, Oscar, Velasco-Hernandez, Talia, Gonzalez, Jessica, Romecin, Paola, Gutierrez-Agüera, Francisco, Roca-Ho, Heleia, Vinyoles, Meritxell, Kowarz, Eric, Marin, Pedro, Rodriguez-Perales, Sandra, Gomez-Marin, Carlos, Perez-Vera, Patricia, Cortes-Ledesma, Felipe, Bigas, Anna, Terron, Andrea, Bueno, Clara, Menendez, Pablo
Publicado 2021

Chd7 is indispensable for mammalian brain development through activation of a neuronal differentiation programme

por Feng, Weijun, Kawauchi, Daisuke, Körkel-Qu, Huiqin, Deng, Huan, Serger, Elisabeth, Sieber, Laura, Lieberman, Jenna Ariel, Jimeno-González, Silvia, Lambo, Sander, Hanna, Bola S., Harim, Yassin, Jansen, Malin, Neuerburg, Anna, Friesen, Olga, Zuckermann, Marc, Rajendran, Vijayanad, Gronych, Jan, Ayrault, Olivier, Korshunov, Andrey, Jones, David T. W., Kool, Marcel, Northcott, Paul A., Lichter, Peter, Cortés-Ledesma, Felipe, Pfister, Stefan M., Liu, Hai-Kun
Publicado 2017