Lymphoblast Oxidative Stress Genes as Potential Biomarkers of Disease Severity and Drug Effect in Friedreich's Ataxia

por Hayashi, Genki, Cortopassi, Gino
Publicado 2016

The Eye Drop Preservative Benzalkonium Chloride Potently Induces Mitochondrial Dysfunction and Preferentially Affects LHON Mutant Cells

por Datta, Sandipan, Baudouin, Christophe, Brignole-Baudouin, Francoise, Denoyer, Alexandre, Cortopassi, Gino A.
Publicado 2017

In Vitro Evaluation of Mitochondrial Function and Estrogen Signaling in Cell Lines Exposed to the Antiseptic Cetylpyridinium Chloride

por Datta, Sandipan, He, Guochun, Tomilov, Alexey, Sahdeo, Sunil, Denison, Michael S., Cortopassi, Gino
Publicado 2017

A descriptive pilot study of cytokine production following stimulation of ex-vivo whole blood with commercial therapeutic feline hydrolyzed diets in individual healthy immunotolera...

por Kathrani, Aarti, Larsen, Jennifer A., Cortopassi, Gino, Datta, Sandipan, Fascetti, Andrea J.
Publicado 2017

Key Glycolytic Enzyme Activities of Skeletal Muscle Are Decreased under Fed and Fasted States in Mice with Knocked Down Levels of Shc Proteins

por Hagopian, Kevork, Tomilov, Alexey A., Kim, Kyoungmi, Cortopassi, Gino A., Ramsey, Jon J.
Publicado 2015

Frataxin deficiency increases cyclooxygenase 2 and prostaglandins in cell and animal models of Friedreich's ataxia

por Hayashi, Genki, Shen, Yan, Pedersen, Theresa L., Newman, John W., Pook, Mark, Cortopassi, Gino
Publicado 2014

Frataxin Deficiency Promotes Excess Microglial DNA Damage and Inflammation that Is Rescued by PJ34

por Shen, Yan, McMackin, Marissa Z., Shan, Yuxi, Raetz, Alan, David, Sheila, Cortopassi, Gino
Publicado 2016

Mice with low levels of Shc proteins display reduced glycolytic and increased gluconeogenic activities in liver

por Hagopian, Kevork, Kim, Kyoungmi, López-Dominguez, José Alberto, Tomilov, Alexey A., Cortopassi, Gino A., Ramsey, Jon J.
Publicado 2016

Dimethyl fumarate dosing in humans increases frataxin expression: A potential therapy for Friedreich’s Ataxia

por Jasoliya, Mittal, Sacca, Francesco, Sahdeo, Sunil, Chedin, Frederic, Pane, Chiara, Brescia Morra, Vincenzo, Filla, Alessandro, Pook, Mark, Cortopassi, Gino
Publicado 2019

A Drug Combination Rescues Frataxin-Dependent Neural and Cardiac Pathophysiology in FA Models

por Abeti, Rosella, Jasoliya, Mittal, Al-Mahdawi, Sahar, Pook, Mark, Gonzalez-Robles, Cristina, Hui, Chun Kiu, Cortopassi, Gino, Giunti, Paola
Publicado 2022

Potential biomarker identification for Friedreich’s ataxia using overlapping gene expression patterns in patient cells and mouse dorsal root ganglion

por McMackin, Marissa Z., Durbin-Johnson, Blythe, Napierala, Marek, Napierala, Jill S., Ruiz, Luis, Napoli, Eleonora, Perlman, Susan, Giulivi, Cecilia, Cortopassi, Gino A.
Publicado 2019

The Histone H3 K4me3, K27me3, and K27ac Genome-Wide Distributions Are Differently Influenced by Sex in Brain Cortexes and Gastrocnemius of the Alzheimer’s Disease PSAPP Mouse Model...

por Casciaro, Francesca, Persico, Giuseppe, Rusin, Martina, Amatori, Stefano, Montgomery, Claire, Rutkowsky, Jennifer R., Ramsey, Jon J., Cortopassi, Gino, Fanelli, Mirco, Giorgio, Marco
Publicado 2021

Synthesis and biochemical characterization of EGF receptor in a water-soluble membrane model system

por Scharadin, Tiffany M., He, Wei, Yiannakou, Yianni, Tomilov, Alexey A., Saldana, Matthew, Cortopassi, Gino A., Carraway, Kermit L., Coleman, Matthew A., Henderson, Paul T.
Publicado 2017

Novel mTORC1 Inhibitors Kill Glioblastoma Stem Cells

por Sandoval, Jose A., Tomilov, Alexey, Datta, Sandipan, Allen, Sonia, O’Donnell, Robert, Sears, Thomas, Woolard, Kevin, Kovalskyy, Dmytro, Angelastro, James M., Cortopassi, Gino
Publicado 2020

Dyclonine rescues frataxin deficiency in animal models and buccal cells of patients with Friedreich's ataxia

por Sahdeo, Sunil, Scott, Brian D., McMackin, Marissa Z., Jasoliya, Mittal, Brown, Brandon, Wulff, Heike, Perlman, Susan L., Pook, Mark A., Cortopassi, Gino A.
Publicado 2014

Identification and functional validation of FDA-approved positive and negative modulators of the mitochondrial calcium uniporter

por De Mario, Agnese, Tosatto, Anna, Hill, Julia Marie, Kriston-Vizi, Janos, Ketteler, Robin, Vecellio Reane, Denis, Cortopassi, Gino, Szabadkai, Gyorgy, Rizzuto, Rosario, Mammucari, Cristina
Publicado 2021

Androgen receptor-dependent regulation of metabolism in high grade bladder cancer cells

por Katleba, Kimberley D., Tsamouri, Maria-Malvina, Jathal, Maitreyee, Baek, Han Bit, Armenta, Rebecca B., Tepper, Clifford G., Cortopassi, Gino, Ghosh, Paramita M., Mudryj, Maria
Publicado 2023

OPA1 Mutation and Late-Onset Cardiomyopathy: Mitochondrial Dysfunction and mtDNA Instability

por Chen, Le, Liu, Tingting, Tran, Alice, Lu, Xiyuan, Tomilov, Alexey A., Davies, Vanessa, Cortopassi, Gino, Chiamvimonvat, Nipavan, Bers, Donald M., Votruba, Marcela, Knowlton, Anne A.
Publicado 2012

Shc depletion stimulates brown fat activity in vivo and in vitro

por Tomilov, Alexey, Bettaieb, Ahmed, Kim, Kyoungmi, Sahdeo, Sunil, Tomilova, Natalia, Lam, Adam, Hagopian, Kevork, Connell, Michelle, Fong, Jennifer, Rowland, Douglas, Griffey, Stephen, Ramsey, Jon, Haj, Fawaz, Cortopassi, Gino
Publicado 2014

PPARα-targeted mitochondrial bioenergetics mediate repair of intestinal barriers at the host–microbe intersection during SIV infection

por Crakes, Katti R., Santos Rocha, Clarissa, Grishina, Irina, Hirao, Lauren A., Napoli, Eleonora, Gaulke, Christopher A., Fenton, Anne, Datta, Sandipan, Arredondo, Juan, Marco, Maria L., Sankaran-Walters, Sumathi, Cortopassi, Gino, Giulivi, Cecilia, Dandekar, Satya
Publicado 2019