Rigosertib ameliorates the effects of oncogenic KRAS signaling in a murine model of myeloproliferative neoplasia

por Baker, Stacey J., Cosenza, Stephen C., Ramana Reddy, M.V., Premkumar Reddy, E.
Publicado 2019

ON01210.Na (Ex-RAD(®)) Mitigates Radiation Damage through Activation of the AKT Pathway

por Kang, Anthony D., Cosenza, Stephen C., Bonagura, Marie, Manair, Manoj, Reddy, M. V. Ramana, Reddy, E. Premkumar
Publicado 2013

Dual Inhibition of CDK4/Rb and PI3K/AKT/mTOR Pathways by ON123300 Induces Synthetic Lethality in Mantle Cell Lymphomas

por Divakar, Saikrishna A., Reddy, M.V. Ramana, Cosenza, Stephen C., Baker, Stacey J., Perumal, Deepak, Antonelli, Anthony C., Brody, Joshua, Akula, Balaiah, Parekh, Samir, Reddy, E. Premkumar
Publicado 2015

Targeting protein kinase CK2 and CDK4/6 pathways with a multi-kinase inhibitor ON108110 suppresses pro-survival signaling and growth in mantle cell lymphoma and T-acute lymphoblast...

por Padgaonkar, Amol, Rechkoblit, Olga, Vasquez-Del Carpio, Rodgrigo, Pallela, Venkat, Venkata Subbaiah, DRC, Cosenza, Stephen C., Baker, Stacey J., Ramana Reddy, M.V., Aggarwal, Aneel, Reddy, E. Premkumar
Publicado 2018

Simultaneous CK2/TNIK/DYRK1 inhibition by 108600 suppresses triple negative breast cancer stem cells and chemotherapy-resistant disease

por Sato, Katsutoshi, Padgaonkar, Amol A., Baker, Stacey J., Cosenza, Stephen C., Rechkoblit, Olga, Subbaiah, D. R. C. Venkata, Domingo-Domenech, Josep, Bartkowski, Alison, Port, Elisa R., Aggarwal, Aneel K., Ramana Reddy, M. V., Irie, Hanna Y., Reddy, E. Premkumar
Publicado 2021

Discovery of 8-Cyclopentyl-2-[4-(4-methyl-piperazin-1-yl)-phenylamino]-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidine-6-carbonitrile (7x) as a Potent Inhibitor of Cyclin-Dependent Kinas...

por Reddy, M. V. Ramana, Akula, Balireddy, Cosenza, Stephen C., Athuluridivakar, Saikrishna, Mallireddigari, Muralidhar R., Pallela, Venkat R., Billa, Vinay K., Subbaiah, D. R. C. Venkata, Bharathi, E. Vijaya, Vasquez-Del Carpio, Rodrigo, Padgaonkar, Amol, Baker, Stacey J., Reddy, E. Premkumar
Publicado 2014