Molecular and Cellular Mechanisms Underlying the Initiation and Progression of Alport Glomerular Pathology

por Cosgrove, Dominic, Madison, Jacob
Publicado 2022

Glomerular basement membrane deposition of collagen α1(III) in Alport glomeruli by mesangial filopodia injures podocytes via aberrant signaling through DDR1 and integrin α2β1

por Madison, Jacob, Wilhelm, Kevin, Meehan, Daniel T, Delimont, Duane, Samuelson, Gina, Cosgrove, Dominic
Publicado 2022

X-Linked Alport Dogs Demonstrate Mesangial Filopodial Invasion of the Capillary Tuft as an Early Event in Glomerular Damage

por Clark, Sabrina D., Nabity, Mary B., Cianciolo, Rachel E., Dufek, Brianna, Cosgrove, Dominic
Publicado 2016

Role for a Novel Usher Protein Complex in Hair Cell Synaptic Maturation

por Zallocchi, Marisa, Meehan, Daniel T., Delimont, Duane, Rutledge, Joseph, Gratton, Michael Anne, Flannery, John, Cosgrove, Dominic
Publicado 2012

Laminin α2-Mediated Focal Adhesion Kinase Activation Triggers Alport Glomerular Pathogenesis

por Delimont, Duane, Dufek, Brianna M., Meehan, Daniel T., Zallocchi, Marisa, Gratton, Michael Anne, Phillips, Grady, Cosgrove, Dominic
Publicado 2014

Light-Induced Translocation of RGS9-1 and Gβ5L in Mouse Rod Photoreceptors

por Tian, Mei, Zallocchi, Marisa, Wang, Weimin, Chen, Ching-Kang, Palczewski, Krzysztof, Delimont, Duane, Cosgrove, Dominic, Peng, You-Wei
Publicado 2013

The usherin mutation c.2299delG leads to its mislocalization and disrupts interactions with whirlin and VLGR1

por Tebbe, Lars, Mwoyosvi, Maggie L., Crane, Ryan, Makia, Mustafa S., Kakakhel, Mashal, Cosgrove, Dominic, Al-Ubaidi, Muayyad R., Naash, Muna I.
Publicado 2023

Stage-Specific Action of Matrix Metalloproteinases Influences Progressive Hereditary Kidney Disease

por Zeisberg, Michael, Khurana, Mona, Rao, Velidi H, Cosgrove, Dominic, Rougier, Jean-Philippe, Werner, Michelle C, Shield, Charles F, Werb, Zena, Kalluri, Raghu
Publicado 2006

RNA-seq analysis of gene expression profiles in isolated stria vascularis from wild-type and Alport mice reveals key pathways underling Alport strial pathogenesis

por Dufek, Brianna, Meehan, Daniel T., Delimont, Duane, Wilhelm, Kevin, Samuelson, Gina, Coenen, Ross, Madison, Jacob, Doyle, Edward, Smyth, Brendan, Phillips, Grady, Gratton, Michael Anne, Cosgrove, Dominic
Publicado 2020

EIAV-Based Retinal Gene Therapy in the shaker1 Mouse Model for Usher Syndrome Type 1B: Development of UshStat

por Zallocchi, Marisa, Binley, Katie, Lad, Yatish, Ellis, Scott, Widdowson, Peter, Iqball, Sharifah, Scripps, Vicky, Kelleher, Michelle, Loader, Julie, Miskin, James, Peng, You-Wei, Wang, Wei-Min, Cheung, Linda, Delimont, Duane, Mitrophanous, Kyriacos A., Cosgrove, Dominic
Publicado 2014