Selective androgen receptor modulators for the treatment of late onset male hypogonadism

por Coss, Christopher C, Jones, Amanda, Hancock, Michael L, Steiner, Mitchell S, Dalton, James T
Publicado 2014

Constitutively Active Androgen Receptor in Hepatocellular Carcinoma

por Montgomery, Emma J., Xing, Enming, Campbell, Moray J., Li, Pui-Kai, Blachly, James S., Tsung, Allan, Coss, Christopher C.
Publicado 2022

Population Pharmacokinetic Analysis from First-in-Human Data for HDAC Inhibitor, REC-2282 (AR-42), in Patients with Solid Tumors and Hematologic Malignancies: A Case Study for Eval...

por Liva, Sophia, Chen, Min, Mortazavi, Amir, Walker, Alison, Wang, Jiang, Dittmar, Kristin, Hofmeister, Craig, Coss, Christopher C., Phelps, Mitch A.
Publicado 2021

The MYC axis in advanced prostate cancer is impacted through concurrent targeting of ERβ and AR using a novel ERβ-selective ligand alongside Enzalutamide

por Gray, Jaimie S., Wani, Sajad A., Hussain, Shahid, Huang, Phoebe, Nayak, Debasis, Long, Mark D., Yates, Clayton, Clinton, Steven K., Bennet, Chad E., Coss, Christopher C., Campbell, Moray J.
Publicado 2023

CD44 positive and sorafenib insensitive hepatocellular carcinomas respond to the ATP-competitive mTOR inhibitor INK128

por Badawi, Mohamed, Kim, Jihye, Dauki, Anees, Sutaria, Dhruvitkumar, Motiwala, Tasneem, Reyes, Ryan, Wani, Nissar, Kolli, Shamalatha, Jiang, Jinmai, Coss, Christopher C., Jacob, Samson T., Phelps, Mitch A., Schmittgen, Thomas D.
Publicado 2018

Discovery and Preclinical Characterization of Novel Small Molecule TRK and ROS1 Tyrosine Kinase Inhibitors for the Treatment of Cancer and Inflammation

por Narayanan, Ramesh, Yepuru, Muralimohan, Coss, Christopher C., Wu, Zhongzhi, Bauler, Matthew N., Barrett, Christina M., Mohler, Michael L., Wang, Yun, Kim, Juhyun, Snyder, Linda M., He, Yali, Levy, Nelson, Miller, Duane D., Dalton, James T.
Publicado 2013

Inhibition of androgen/AR signaling inhibits diethylnitrosamine (DEN) induced tumour initiation and remodels liver immune cell networks

por Helms, Timothy H., Mullins, Riley D., Thomas-Ahner, Jennifer M., Kulp, Samuel K., Campbell, Moray J., Lucas, Fabienne, Schmidt, Nathan, LeMoine, Dana M., Getaneh, Surafel, Xie, Zhiliang, Phelps, Mitch A., Clinton, Steven K., Coss, Christopher C.
Publicado 2021

Target specificity, in vivo pharmacokinetics, and efficacy of the putative STAT3 inhibitor LY5 in osteosarcoma, Ewing's sarcoma, and rhabdomyosarcoma

por Yu, Peter Y., Gardner, Heather L., Roberts, Ryan, Cam, Hakan, Hariharan, Seethalakshmi, Ren, Ling, LeBlanc, Amy K., Xiao, Hui, Lin, Jiayuh, Guttridge, Denis C., Mo, Xiaokui, Bennett, Chad E., Coss, Christopher C., Ling, Yonghua, Phelps, Mitch A., Houghton, Peter, London, Cheryl A.
Publicado 2017

Activity of Estrogen Receptor β Agonists in Therapy-Resistant Estrogen Receptor-Positive Breast Cancer

por Datta, Jharna, Willingham, Natalie, Manouchehri, Jasmine M., Schnell, Patrick, Sheth, Mirisha, David, Joel J., Kassem, Mahmoud, Wilson, Tyler A., Radomska, Hanna S., Coss, Christopher C., Bennett, Chad E., Ganju, Ramesh K., Sardesai, Sagar D., Lustberg, Maryam, Ramaswamy, Bhuvaneswari, Stover, Daniel G., Cherian, Mathew A.
Publicado 2022

Overcoming resistance to anabolic SARM therapy in experimental cancer cachexia with an HDAC inhibitor

por Liva, Sophia G, Tseng, Yu‐Chou, Dauki, Anees M, Sovic, Michael G, Vu, Trang, Henderson, Sally E, Kuo, Yi‐Chiu, Benedict, Jason A, Zhang, Xiaoli, Remaily, Bryan C, Kulp, Samuel K, Campbell, Moray, Bekaii‐Saab, Tanios, Phelps, Mitchell A, Chen, Ching‐Shih, Coss, Christopher C
Publicado 2020

Murine cancer cachexia models replicate elevated catabolic pembrolizumab clearance in humans

por Castillo, Alyssa Marie M., Vu, Trang T., Liva, Sophia G., Chen, Min, Xie, Zhiliang, Thomas, Justin, Remaily, Bryan, Guo, Yizhen, Subrayan, Uma L., Costa, Travis, Helms, Timothy H., Irby, Donald J., Kim, Kyeongmin, Owen, Dwight H., Kulp, Samuel K., Mace, Thomas A., Phelps, Mitch A., Coss, Christopher C.
Publicado 2021

Preclinical Evaluation of the Novel BTK Inhibitor Acalabrutinib in Canine Models of B-Cell Non-Hodgkin Lymphoma

por Harrington, Bonnie K., Gardner, Heather L., Izumi, Raquel, Hamdy, Ahmed, Rothbaum, Wayne, Coombes, Kevin R., Covey, Todd, Kaptein, Allard, Gulrajani, Michael, Van Lith, Bart, Krejsa, Cecile, Coss, Christopher C., Russell, Duncan S., Zhang, Xiaoli, Urie, Bridget K., London, Cheryl A., Byrd, John C., Johnson, Amy J., Kisseberth, William C.
Publicado 2016

The Neonatal Fc Receptor Is Elevated in Monocyte-Derived Immune Cells in Pancreatic Cancer

por Thomas, Justin, Torok, Molly A., Agrawal, Kriti, Pfau, Timothy, Vu, Trang T., Lyberger, Justin, Chang, Hsiaochi, Castillo, Alyssa Marie M., Chen, Min, Remaily, Bryan, Kim, Kyeongmin, Xie, Zhiliang, Dillhoff, Mary E., Kulp, Samuel K., Behbehani, Gregory K., Cruz-Monserrate, Zobeida, Ganesan, Latha P., Owen, Dwight H., Phelps, Mitch A., Coss, Christopher C., Mace, Thomas A.
Publicado 2022

Physical Activity Delays Obesity-Associated Pancreatic Ductal Adenocarcinoma in Mice and Decreases Inflammation

por Pita-Grisanti, Valentina, Dubay, Kelly, Lahooti, Ali, Badi, Niharika, Ueltschi, Olivia, Gumpper-Fedus, Kristyn, Hsueh, Hsiang-Yin, Lahooti, Ila, Chavez-Tomar, Myrriah, Terhorst, Samantha, Knoblaugh, Sue E., Cao, Lei, Huang, Wei, Coss, Christopher C., Mace, Thomas A., Choueiry, Fouad, Hinton, Alice, Mitchell, Jennifer M, Schmandt, Rosemarie, Grinsfelder, Michaela Onstad, Basen-Engquist, Karen, Cruz-Monserrate, Zobeida
Publicado 2023