Single-Cell Elastography: Probing for Disease with the Atomic Force Microscope

por Costa, Kevin D.
Publicado 2004

Rianú: Multi-tissue tracking software for increased throughput of engineered cardiac tissue screening

por Murphy, Jack F., Costa, Kevin D., Turnbull, Irene C.
Publicado 2023

Computational design of custom therapeutic cells to correct failing human cardiomyocytes

por Tieu, Andrew, Phillips, Katherine G., Costa, Kevin D., Mayourian, Joshua
Publicado 2023

Modeling Electrophysiological Coupling and Fusion between Human Mesenchymal Stem Cells and Cardiomyocytes

por Mayourian, Joshua, Savizky, Ruben M., Sobie, Eric A., Costa, Kevin D.
Publicado 2016

Physical developmental cues for the maturation of human pluripotent stem cell-derived cardiomyocytes

por Zhu, Renjun, Blazeski, Adriana, Poon, Ellen, Costa, Kevin D, Tung, Leslie, Boheler, Kenneth R
Publicado 2014

Human Engineered Cardiac Tissues Created Using Induced Pluripotent Stem Cells Reveal Functional Characteristics of BRAF-Mediated Hypertrophic Cardiomyopathy

por Cashman, Timothy J., Josowitz, Rebecca, Johnson, Bryce V., Gelb, Bruce D., Costa, Kevin D.
Publicado 2016

Rho Kinase Regulates Aortic Vascular Smooth Muscle Cell Stiffness Via Actin/SRF/Myocardin in Hypertension

por Zhou, Ning, Lee, Jia-Jye, Stoll, Shaunrick, Ma, Ben, Costa, Kevin D., Qiu, Hongyu
Publicado 2017

In silico Cell Therapy Model Restores Failing Human Myocyte Electrophysiology and Calcium Cycling in Fibrotic Myocardium

por Phillips, Katherine G., Turnbull, Irene C., Hajjar, Roger J., Costa, Kevin D., Mayourian, Joshua
Publicado 2022

15000 Exploring team science, professional networks, and innovation success in the THRIVE COVID-19 fellowship program

por Fattah, Layla, Gabrilove, Janice, Oemke, Holly, Borrello, Joseph, Baker, Turner, Costa, Kevin D., Putrino, David, Costa, Anthony
Publicado 2021

Inhibition of SRF/myocardin reduces aortic stiffness by targeting vascular smooth muscle cell stiffening in hypertension

por Zhou, Ning, Lee, Jia-Jye, Stoll, Shaunrick, Ma, Ben, Wiener, Robert, Wang, Charles, Costa, Kevin D., Qiu, Hongyu
Publicado 2017

Machine Learning of Human Pluripotent Stem Cell-Derived Engineered Cardiac Tissue Contractility for Automated Drug Classification

por Lee, Eugene K., Tran, David D., Keung, Wendy, Chan, Patrick, Wong, Gabriel, Chan, Camie W., Costa, Kevin D., Li, Ronald A., Khine, Michelle
Publicado 2017

CXCR4 and CXCR7 play distinct roles in cardiac lineage specification and pharmacologic β-adrenergic response

por Ceholski, Delaine K., Turnbull, Irene C., Pothula, Venu, Lecce, Laura, Jarrah, Andrew A., Kho, Changwon, Lee, Ahyoung, Hadri, Lahouaria, Costa, Kevin D., Hajjar, Roger J., Tarzami, Sima T.
Publicado 2017

Adult human cardiac stem cell supplementation effectively increases contractile function and maturation in human engineered cardiac tissues

por Murphy, Jack F., Mayourian, Joshua, Stillitano, Francesca, Munawar, Sadek, Broughton, Kathleen M., Agullo-Pascual, Esperanza, Sussman, Mark A., Hajjar, Roger J., Costa, Kevin D., Turnbull, Irene C.
Publicado 2019

Single-cell RNA sequencing reveals maturation trajectory in human pluripotent stem cell-derived cardiomyocytes in engineered tissues

por Cheng, Shangli, Brenière-Letuffe, David, Ahola, Virpi, Wong, Andy O.T., Keung, Hoi Yee, Gurung, Bimal, Zheng, Zongli, Costa, Kevin D., Lieu, Deborah K., Keung, Wendy, Li, Ronald A.
Publicado 2023

Adverse effects of hydroxychloroquine and azithromycin on contractility and arrhythmogenicity revealed by human engineered cardiac tissues

por Wong, Andy On-Tik, Gurung, Bimal, Wong, Wing Sum, Mak, Suet Yee, Tse, Wan Wai, Li, Chloe M., Lieu, Deborah K., Costa, Kevin D., Li, Ronald A., Hajjar, Roger J.
Publicado 2021

Adverse effects of hydroxychloroquine and azithromycin on contractility and arrhythmogenicity revealed by human engineered cardiac tissues

por Wong, Andy O.-T., Gurung, Bimal, Wong, Wing Sum, Mak, Suet Yee, Tse, Wan Wai, Li, Chloe M., Lieu, Deborah K., Costa, Kevin D., Li, Ronald A., Hajjar, Roger J.
Publicado 2021

Combinatorial Treatment of Human Cardiac Engineered Tissues With Biomimetic Cues Induces Functional Maturation as Revealed by Optical Mapping of Action Potentials and Calcium Trans...

por Wong, Andy On-Tik, Wong, Nicodemus, Geng, Lin, Chow, Maggie Zi-ying, Lee, Eugene K., Wu, Hongkai, Khine, Michelle, Kong, Chi-Wing, Costa, Kevin D., Keung, Wendy, Cheung, Yiu-Fai, Li, Ronald A.
Publicado 2020

Modulation of chromatin remodeling proteins SMYD1 and SMARCD1 promotes contractile function of human pluripotent stem cell-derived ventricular cardiomyocyte in 3D-engineered cardia...

por Chow, Maggie Zi-Ying, Sadrian, Stephanie N., Keung, Wendy, Geng, Lin, Ren, Lihuan, Kong, Chi-Wing, Wong, Andy On-Tik, Hulot, Jean-Sebastien, Chen, Christopher S., Costa, Kevin D., Hajjar, Roger J., Li, Ronald A.
Publicado 2019

Correlation between frataxin expression and contractility revealed by in vitro Friedreich’s ataxia cardiac tissue models engineered from human pluripotent stem cells

por Wong, Andy On-Tik, Wong, Gabriel, Shen, Michael, Chow, Maggie Zi-Ying, Tse, Wan Wai, Gurung, Bimal, Mak, Suet Yee, Lieu, Deborah K., Costa, Kevin D., Chan, Camie W., Martelli, Alain, Nabhan, Joseph F., Li, Ronald A.
Publicado 2019