Mining Methylation for Early Detection of Common Cancers

por Brena, Romulo M, Plass, Christoph, Costello, Joseph F
Publicado 2006

Hypertonic saline reduces inflammation and enhances the resolution of oleic acid induced acute lung injury

por Kennedy, Muiris T, Higgins, Brendan D, Costello, Joseph F, Curtin, William A, Laffey, John G
Publicado 2008

Saturation mutagenesis of twenty disease-associated regulatory elements at single base-pair resolution

por Kircher, Martin, Xiong, Chenling, Martin, Beth, Schubach, Max, Inoue, Fumitaka, Bell, Robert J. A., Costello, Joseph F., Shendure, Jay, Ahituv, Nadav
Publicado 2019

GABP couples oncogene signaling to telomere regulation in TERT promoter mutant cancer

por McKinney, Andrew M., Mathur, Radhika, Stevers, Nicholas O., Molinaro, Annette M., Chang, Susan M., Phillips, Joanna J., Costello, Joseph F.
Publicado 2022

Mutant IDH1 expression is associated with down-regulation of monocarboxylate transporters

por Viswanath, Pavithra, Najac, Chloe, Izquierdo, Jose L., Pankov, Aleksandr, Hong, Chibo, Eriksson, Pia, Costello, Joseph F., Pieper, Russell O., Ronen, Sabrina M.
Publicado 2016

Early Noninvasive Metabolic Biomarkers of Mutant IDH Inhibition in Glioma

por Radoul, Marina, Hong, Donghyun, Gillespie, Anne Marie, Najac, Chloé, Viswanath, Pavithra, Pieper, Russell O., Costello, Joseph F., Luchman, Hema Artee, Ronen, Sabrina M.
Publicado 2021

Hyperpolarized δ-[1- (13)C]gluconolactone imaging visualizes response to TERT or GABPB1 targeting therapy for glioblastoma

por Minami, Noriaki, Hong, Donghyun, Taglang, Celine, Batsios, Georgios, Gillespie, Anne Marie, Viswanath, Pavithra, Stevers, Nicholas, Barger, Carter J., Costello, Joseph F., Ronen, Sabrina M.
Publicado 2023

IL-1 TERT PROMOTER C228T MUTATION IN NEURAL PROGENITORS CONFERS GROWTH ADVANTAGE FOLLOWING TELOMERE SHORTENING IN VIVO

por Furnari, Frank, Miki, Shunichiro, Koga, Tomoyuki, Mckinney, Andrew M, Parisian, Alison D, Tadokoro, Takahiro, Vadla, Raghavendra, Masala, Martin, Hevner, Robert F, Costello, Joseph F
Publicado 2022

Molecular signatures define two main classes of meningiomas

por Carvalho, Lucia Helena, Smirnov, Ivan, Baia, Gilson S, Modrusan, Zora, Smith, Justin S, Jun, Peter, Costello, Joseph F, McDermott, Michael W, VandenBerg, Scott R, Lal, Anita
Publicado 2007

To ERV Is Human: A Phenotype-Wide Scan Linking Polymorphic Human Endogenous Retrovirus-K Insertions to Complex Phenotypes

por Wallace, Amelia D., Wendt, George A., Barcellos, Lisa F., de Smith, Adam J., Walsh, Kyle M., Metayer, Catherine, Costello, Joseph F., Wiemels, Joseph L., Francis, Stephen S.
Publicado 2018

Estimating absolute methylation levels at single-CpG resolution from methylation enrichment and restriction enzyme sequencing methods

por Stevens, Michael, Cheng, Jeffrey B., Li, Daofeng, Xie, Mingchao, Hong, Chibo, Maire, Cécile L., Ligon, Keith L., Hirst, Martin, Marra, Marco A., Costello, Joseph F., Wang, Ting
Publicado 2013

Mapping of Variable DNA Methylation Across Multiple Cell Types Defines a Dynamic Regulatory Landscape of the Human Genome

por Gu, Junchen, Stevens, Michael, Xing, Xiaoyun, Li, Daofeng, Zhang, Bo, Payton, Jacqueline E., Oltz, Eugene M., Jarvis, James N., Jiang, Kaiyu, Cicero, Theodore, Costello, Joseph F., Wang, Ting
Publicado 2016

Non-invasive assessment of telomere maintenance mechanisms in brain tumors

por Viswanath, Pavithra, Batsios, Georgios, Mukherjee, Joydeep, Gillespie, Anne Marie, Larson, Peder E. Z., Luchman, H. Artee, Phillips, Joanna J., Costello, Joseph F., Pieper, Russell O., Ronen, Sabrina M.
Publicado 2021

Characterization of the Contradictory Chromatin Signatures at the 3′ Exons of Zinc Finger Genes

por Blahnik, Kimberly R., Dou, Lei, Echipare, Lorigail, Iyengar, Sushma, O'Geen, Henriette, Sanchez, Erica, Zhao, Yongjun, Marra, Marco A., Hirst, Martin, Costello, Joseph F., Korf, Ian, Farnham, Peggy J.
Publicado 2011

Spark: A navigational paradigm for genomic data exploration

por Nielsen, Cydney B., Younesy, Hamid, O'Geen, Henriette, Xu, Xiaoqin, Jackson, Andrew R., Milosavljevic, Aleksandar, Wang, Ting, Costello, Joseph F., Hirst, Martin, Farnham, Peggy J., Jones, Steven J.M.
Publicado 2012

Conserved features of TERT promoter duplications reveal an activation mechanism that mimics hotspot mutations in cancer

por Barger, Carter J., Suwala, Abigail K., Soczek, Katarzyna M., Wang, Albert S., Kim, Min Y., Hong, Chibo, Doudna, Jennifer A., Chang, Susan M., Phillips, Joanna J., Solomon, David A., Costello, Joseph F.
Publicado 2022

Genome-wide DNA methylation is predictive of outcome in juvenile myelomonocytic leukemia

por Stieglitz, Elliot, Mazor, Tali, Olshen, Adam B., Geng, Huimin, Gelston, Laura C., Akutagawa, Jon, Lipka, Daniel B., Plass, Christoph, Flotho, Christian, Chehab, Farid F., Braun, Benjamin S., Costello, Joseph F., Loh, Mignon L.
Publicado 2017

Cancer-specific loss of TERT activation sensitizes glioblastoma to DNA damage

por Amen, Alexandra M., Fellmann, Christof, Soczek, Katarzyna M., Ren, Shawn M., Lew, Rachel J., Knott, Gavin J., Park, Jesslyn E., McKinney, Andrew M., Mancini, Andrew, Doudna, Jennifer A., Costello, Joseph F.
Publicado 2021

Patient-derived cells from recurrent tumors that model the evolution of IDH-mutant glioma

por Jones, Lindsey E, Hilz, Stephanie, Grimmer, Matthew R, Mazor, Tali, Najac, Chloé, Mukherjee, Joydeep, McKinney, Andrew, Chow, Tracy, Pieper, Russell O, Ronen, Sabrina M, Chang, Susan M, Phillips, Joanna J, Costello, Joseph F
Publicado 2020

Genetic and Epigenetic Regulation of the Organic Cation Transporter 3, SLC22A3

por Chen, Ligong, Hong, Chibo, Chen, Eugene C., Yee, Sook Wah, Xu, Lu, Almof, Emil U., Wen, Christopher, Fujii, Kacyn, Johns, Susan J., Stryke, Doug, Ferrin, Thomas E., Simko, Jeff, Chen, Xin, Costello, Joseph F., Giacomini, Kathleen M.
Publicado 2012