Molecular Advances in the Treatment of Advanced Gastrointestinal Stromal Tumor

por Venkataraman, Vinayak, George, Suzanne, Cote, Gregory M
Publicado 2023

Multimodality local ablative therapy of 23 lung metastases with surgical resection and percutaneous cryoablation in a patient with Li-Fraumeni Syndrome: A case report

por Saenger, Jonathan A., Tahir, Ismail, Födinger, Manuela, Cote, Gregory M., Muniappan, Ashok, Fintelmann, Florian J.
Publicado 2023

Inhibition of ATR-Chk1 signaling blocks DNA double-strand-break repair and induces cytoplasmic vacuolization in metastatic osteosarcoma

por Li, Xiaoyang, Dean, Dylan C., Cote, Gregory M., Zou, Lee, Hornicek, Francis J., Yu, Shengji, Duan, Zhenfeng
Publicado 2020

Targeting EZH2-mediated methylation of H3K27 inhibits proliferation and migration of Synovial Sarcoma in vitro

por Shen, Jacson K., Cote, Gregory M., Gao, Yan, Choy, Edwin, Mankin, Henry J., Hornicek, Francis J., Duan, Zhenfeng
Publicado 2016

Pseudoprogression of Malignant Peripheral Nerve Sheath Tumor in Patient with Neurofibromatosis Type 1, a Case Report

por Lessing, Andrés J., Cote, Gregory M., DeLaney, Thomas F., Plotkin, Scott R., Raskin, Kevin A., Lessing, Juan N.
Publicado 2021

Myxoid Liposarcoma: Treatment Outcomes from Chemotherapy and Radiation Therapy

por Chowdhry, Varun, Goldberg, Saveli, DeLaney, Thomas F., Cote, Gregory M., Chebib, Ivan, Kim, Jason, Lozano-Calderón, Santiago A., De Amorim Bernstein, Karen
Publicado 2018

CD44 is a direct target of miR-199a-3p and contributes to aggressive progression in osteosarcoma

por Gao, Yan, Feng, Yong, Shen, Jacson K., Lin, Min, Choy, Edwin, Cote, Gregory M., Harmon, David C., Mankin, Henry J., Hornicek, Francis J., Duan, Zhenfeng
Publicado 2015

Phase II Study of Cabozantinib in Patients With Bone Metastasis

por Choy, Edwin, Cote, Gregory M, Michaelson, M Dror, Wirth, Lori, Gainor, Justin F, Muzikansky, Alona, Sequist, Lecia V, Sullivan, Ryan J, Fidias, Panagiotis M, Shaw, Alice, Heist, Rebecca S
Publicado 2022

Genotyping Cancer-Associated Genes in Chordoma Identifies Mutations in Oncogenes and Areas of Chromosomal Loss Involving CDKN2A, PTEN, and SMARCB1

por Choy, Edwin, MacConaill, Laura E., Cote, Gregory M., Le, Long P., Shen, Jacson K., Nielsen, Gunnlaugur P., Iafrate, Anthony J., Garraway, Levi A., Hornicek, Francis J., Duan, Zhenfeng
Publicado 2014

Prognostic Factors in Dedifferentiated Chondrosarcoma: A Retrospective Analysis of a Large Series Treated at a Single Institution

por Miao, Ruoyu, Choy, Edwin, Raskin, Kevin A., Schwab, Joseph H., Nielsen, Gunnlaugur Petur, Deshpande, Vikram, Chebib, Ivan, DeLaney, Thomas F., Hornicek, Francis J., Cote, Gregory M., Chen, Yen-Lin E.
Publicado 2019

Phase II study of olaparib in patients with refractory Ewing sarcoma following failure of standard chemotherapy

por Choy, Edwin, Butrynski, James E, Harmon, David C, Morgan, Jeffrey A, George, Suzanne, Wagner, Andrew J, D’Adamo, David, Cote, Gregory M, Flamand, Yael, Benes, Cyril H, Haber, Daniel A, Baselga, Jose M, Demetri, George D
Publicado 2014

A First‐in‐Human Phase I Study of OPB‐111077, a Small‐Molecule STAT3 and Oxidative Phosphorylation Inhibitor, in Patients with Advanced Cancers

por Tolcher, Anthony, Flaherty, Keith, Shapiro, Geoffrey I., Berlin, Jordan, Witzig, Thomas, Habermann, Thomas, Bullock, Andrea, Rock, Edwin, Elekes, Agnes, Lin, Chester, Kostic, Dusan, Ohi, Naoto, Rasco, Drew, Papadopoulos, Kyriakos P., Patnaik, Amita, Smith, Lon, Cote, Gregory M.
Publicado 2018

MicroRNA-mRNA networks define translatable molecular outcome phenotypes in osteosarcoma

por Lietz, Christopher E., Garbutt, Cassandra, Barry, William T., Deshpande, Vikram, Chen, Yen-Lin, Lozano-Calderon, Santiago A., Wang, Yaoyu, Lawney, Brian, Ebb, David, Cote, Gregory M., Duan, Zhenfeng, Hornicek, Francis J., Choy, Edwin, Petur Nielsen, G., Haibe-Kains, Benjamin, Quackenbush, John, Spentzos, Dimitrios
Publicado 2020

Genome-wide DNA methylation patterns reveal clinically relevant predictive and prognostic subtypes in human osteosarcoma

por Lietz, Christopher E., Newman, Erik T., Kelly, Andrew D., Xiang, David H., Zhang, Ziying, Luscko, Caroline A., Lozano-Calderon, Santiago A., Ebb, David H., Raskin, Kevin A., Cote, Gregory M., Choy, Edwin, Nielsen, G. Petur, Haibe-Kains, Benjamin, Aryee, Martin J., Spentzos, Dimitrios
Publicado 2022

Targeting Sporadic and Neurofibromatosis Type 1 (NF1) Related Refractory Malignant Peripheral Nerve Sheath Tumors (MPNST) in a Phase II Study of Everolimus in Combination with Beva...

por Widemann, Brigitte C., Lu, Yao, Reinke, Denise, Okuno, Scott H., Meyer, Christian F., Cote, Gregory M., Chugh, Rashmi, Milhem, Mohammed M., Hirbe, Angela C., Kim, AeRang, Turpin, Brian, Pressey, Joseph G., Dombi, Eva, Jayaprakash, Nalini, Helman, Lee J., Onwudiwe, Ndidi, Cichowski, Karen, Perentesis, John P.
Publicado 2019

Development and Preliminary Clinical Activity of PD-1-Guided CTLA-4 Blocking Bispecific DART Molecule

por Berezhnoy, Alexey, Sumrow, Bradley J., Stahl, Kurt, Shah, Kalpana, Liu, Daorong, Li, Jonathan, Hao, Su-Shin, De Costa, Anushka, Kaul, Sanjeev, Bendell, Johanna, Cote, Gregory M., Luke, Jason J., Sanborn, Rachel E., Sharma, Manish R., Chen, Francine, Li, Hua, Diedrich, Gundo, Bonvini, Ezio, Moore, Paul A.
Publicado 2020

Ivosidenib in Isocitrate Dehydrogenase 1–Mutated Advanced Glioma

por Mellinghoff, Ingo K., Ellingson, Benjamin M., Touat, Mehdi, Maher, Elizabeth, De La Fuente, Macarena I., Holdhoff, Matthias, Cote, Gregory M., Burris, Howard, Janku, Filip, Young, Robert J., Huang, Raymond, Jiang, Liewen, Choe, Sung, Fan, Bin, Yen, Katharine, Lu, Min, Bowden, Chris, Steelman, Lori, Pandya, Shuchi S., Cloughesy, Timothy F., Wen, Patrick Y.
Publicado 2020

Vorasidenib, a Dual Inhibitor of Mutant IDH1/2, in Recurrent or Progressive Glioma; Results of a First-in-Human Phase I Trial

por Mellinghoff, Ingo K., Penas-Prado, Marta, Peters, Katherine B., Burris, Howard A., Maher, Elizabeth A., Janku, Filip, Cote, Gregory M., de la Fuente, Macarena I., Clarke, Jennifer L., Ellingson, Benjamin M., Chun, Saewon, Young, Robert J., Liu, Hua, Choe, Sung, Lu, Min, Le, Kha, Hassan, Islam, Steelman, Lori, Pandya, Shuchi S., Cloughesy, Timothy F., Wen, Patrick Y.
Publicado 2021

Camonsertib in DNA damage response-deficient advanced solid tumors: phase 1 trial results

por Yap, Timothy A., Fontana, Elisa, Lee, Elizabeth K., Spigel, David R., Højgaard, Martin, Lheureux, Stephanie, Mettu, Niharika B., Carneiro, Benedito A., Carter, Louise, Plummer, Ruth, Cote, Gregory M., Meric-Bernstam, Funda, O’Connell, Joseph, Schonhoft, Joseph D., Wainszelbaum, Marisa, Fretland, Adrian J., Manley, Peter, Xu, Yi, Ulanet, Danielle, Rimkunas, Victoria, Zinda, Mike, Koehler, Maria, Silverman, Ian M., Reis-Filho, Jorge S., Rosen, Ezra
Publicado 2023

Results from Phase I Extension Study Assessing Pexidartinib Treatment in Six Cohorts with Solid Tumors including TGCT, and Abnormal CSF1 Transcripts in TGCT

por Tap, William D., Singh, Arun S., Anthony, Stephen Patrick, Sterba, Mike, Zhang, Chao, Healey, John H., Chmielowski, Bartosz, Cohn, Allen Lee, Shapiro, Geoffrey I., Keedy, Vicki L., Wainberg, Zev A., Puzanov, Igor, Cote, Gregory M., Wagner, Andrew J., Braiteh, Fadi, Sherman, Eric, Hsu, Henry H., Peterfy, Charles, Gelhorn, Heather L., Ye, Xin, Severson, Paul, West, Brian L., Lin, Paul S., Tong-Starksen, Sandra
Publicado 2022