Factors Which Contribute to the Immunogenicity of Non-replicating Adenoviral Vectored Vaccines

por Coughlan, Lynda
Publicado 2020

Snatching the Crown from SARS-CoV-2

por Coughlan, Lynda
Publicado 2020

Caught in a trap: How pre-clinical studies in laboratory mice exaggerate vaccine responses

por Coughlan, Lynda
Publicado 2021

Measuring Cellular Immunity to Influenza: Methods of Detection, Applications and Challenges

por Coughlan, Lynda, Lambe, Teresa
Publicado 2015

Adenovirus-based vaccines—a platform for pandemic preparedness against emerging viral pathogens

por Coughlan, Lynda, Kremer, Eric J., Shayakhmetov, Dmitry M.
Publicado 2022

Adenoviral Vectors as Vaccines for Emerging Avian Influenza Viruses

por Kerstetter, Lucas J., Buckley, Stephen, Bliss, Carly M., Coughlan, Lynda
Publicado 2021

Introduction of two prolines and removal of the polybasic cleavage site leads to optimal efficacy of a recombinant spike based SARS-CoV-2 vaccine in the mouse model

por Amanat, Fatima, Strohmeier, Shirin, Rathnasinghe, Raveen, Schotsaert, Michael, Coughlan, Lynda, García-Sastre, Adolfo, Krammer, Florian
Publicado 2020

Introduction of Two Prolines and Removal of the Polybasic Cleavage Site Lead to Higher Efficacy of a Recombinant Spike-Based SARS-CoV-2 Vaccine in the Mouse Model

por Amanat, Fatima, Strohmeier, Shirin, Rathnasinghe, Raveen, Schotsaert, Michael, Coughlan, Lynda, García-Sastre, Adolfo, Krammer, Florian
Publicado 2021

Murine Monoclonal Antibodies against the Receptor Binding Domain of SARS-CoV-2 Neutralize Authentic Wild-Type SARS-CoV-2 as Well as B.1.1.7 and B.1.351 Viruses and Protect In Vivo...

por Amanat, Fatima, Strohmeier, Shirin, Lee, Wen-Hsin, Bangaru, Sandhya, Ward, Andrew B., Coughlan, Lynda, Krammer, Florian
Publicado 2021

Biodistribution and inflammatory profiles of novel penton and hexon double-mutant serotype 5 adenoviruses

por Bradshaw, Angela C., Coughlan, Lynda, Miller, Ashley M., Alba, Raul, van Rooijen, Nico, Nicklin, Stuart A., Baker, Andrew H.
Publicado 2012

Clinical Assessment of a Novel Recombinant Simian Adenovirus ChAdOx1 as a Vectored Vaccine Expressing Conserved Influenza A Antigens

por Antrobus, Richard D, Coughlan, Lynda, Berthoud, Tamara K, Dicks, Matthew D, Hill, Adrian VS, Lambe, Teresa, Gilbert, Sarah C
Publicado 2014

Tropism-Modification Strategies for Targeted Gene Delivery Using Adenoviral Vectors

por Coughlan, Lynda, Alba, Raul, Parker, Alan L., Bradshaw, Angela C., McNeish, Iain A., Nicklin, Stuart A., Baker, Andrew H.
Publicado 2010

Differential immunogenicity between HAdV-5 and chimpanzee adenovirus vector ChAdOx1 is independent of fiber and penton RGD loop sequences in mice

por Dicks, Matthew D. J., Spencer, Alexandra J., Coughlan, Lynda, Bauza, Karolis, Gilbert, Sarah C., Hill, Adrian V. S., Cottingham, Matthew G.
Publicado 2015

Pseudotyped αvβ6 integrin-targeted adenovirus vectors for ovarian cancer therapies

por Uusi-Kerttula, Hanni, Davies, James, Coughlan, Lynda, Hulin-Curtis, Sarah, Jones, Rachel, Hanna, Louise, Chester, John D., Parker, Alan L.
Publicado 2016

Comparison of Transgenic and Adenovirus hACE2 Mouse Models for SARS-CoV-2 Infection

por Rathnasinghe, Raveen, Strohmeier, Shirin, Amanat, Fatima, Gillespie, Virginia L., Krammer, Florian, García-Sastre, Adolfo, Coughlan, Lynda, Schotsaert, Michael, Uccellini, Melissa
Publicado 2020

Comparison of transgenic and adenovirus hACE2 mouse models for SARS-CoV-2 infection

por Rathnasinghe, Raveen, Strohmeier, Shirin, Amanat, Fatima, Gillespie, Virginia L., Krammer, Florian, García-Sastre, Adolfo, Coughlan, Lynda, Schotsaert, Michael, Uccellini, Melissa B.
Publicado 2020

Diversity within the adenovirus fiber knob hypervariable loops influences primary receptor interactions

por Baker, Alexander T., Greenshields-Watson, Alexander, Coughlan, Lynda, Davies, James A., Uusi-Kerttula, Hanni, Cole, David K., Rizkallah, Pierre J., Parker, Alan L.
Publicado 2019

Vaccination with SARS-CoV-2 variants of concern protects mice from challenge with wild-type virus

por Amanat, Fatima, Strohmeier, Shirin, Meade, Philip S., Dambrauskas, Nicholas, Mühlemann, Barbara, Smith, Derek J., Vigdorovich, Vladimir, Sather, D. Noah, Coughlan, Lynda, Krammer, Florian
Publicado 2021

Enhancing the protection of influenza virus vaccines with BECC TLR4 adjuvant in aged mice

por Haupt, Robert, Baracco, Lauren, Harberts, Erin M., Loganathan, Madhumathi, Kerstetter, Lucas J., Krammer, Florian, Coughlan, Lynda, Ernst, Robert K., Frieman, Matthew B.
Publicado 2023

Requirements for Receptor Engagement during Infection by Adenovirus Complexed with Blood Coagulation Factor X

por Bradshaw, Angela C., Parker, Alan L., Duffy, Margaret R., Coughlan, Lynda, van Rooijen, Nico, Kähäri, Veli-Matti, Nicklin, Stuart A., Baker, Andrew H.
Publicado 2010