Methylglyoxal Forms Diverse Mercaptomethylimidazole Crosslinks with Thiol and Guanidine Pairs in Endogenous Metabolites and Proteins

por Coukos, John S., Moellering, Raymond E.
Publicado 2021

PARK7 Catalyzes Stereospecific Detoxification of Methylglyoxal Consistent with Glyoxalase and Not Deglycase Function

por Coukos, John S., Lee, Chris W., Pillai, Kavya S., Shah, Hardik, Moellering, Raymond E.
Publicado 2023

Widespread, Reversible Cysteine Modification by Methylglyoxal Regulates Metabolic Enzyme Function

por Coukos, John S., Lee, Chris W., Pillai, Kavya S., Liu, Kimberly J., Moellering, Raymond E.
Publicado 2022

A metabolite-derived protein modification integrates glycolysis with KEAP1-NRF2 signaling

por Bollong, Michael J., Lee, Gihoon, Coukos, John S., Yun, Hwayoung, Zambaldo, Claudio, Chang, Jae Won, Chin, Emily N., Ahmad, Insha, Chatterjee, Arnab K., Lairson, Luke L., Schultz, Peter G., Moellering, Raymond E.
Publicado 2018

Synthetic antibodies against BRIL as universal fiducial marks for single−particle cryoEM structure determination of membrane proteins

por Mukherjee, Somnath, Erramilli, Satchal K., Ammirati, Mark, Alvarez, Frances J. D., Fennell, Kimberly F., Purdy, Michael D., Skrobek, Blazej M., Radziwon, Katarzyna, Coukos, John, Kang, Yanyong, Dutka, Przemysław, Gao, Xiang, Qiu, Xiayang, Yeager, Mark, Eric Xu, H., Han, Seungil, Kossiakoff, Anthony A.
Publicado 2020

LKB1-Dependent Regulation of TPI1 Creates a Divergent Metabolic Liability between Human and Mouse Lung Adenocarcinoma

por Stein, Benjamin D., Ferrarone, John R., Gardner, Eric E., Chang, Jae Won, Wu, David, Hollstein, Pablo E., Liang, Roger J., Yuan, Min, Chen, Qiuying, Coukos, John S., Sindelar, Miriam, Ngo, Bryan, Gross, Steven S., Shaw, Reuben J., Zhang, Chen, Asara, John M., Moellering, Raymond E., Varmus, Harold, Cantley, Lewis C.
Publicado 2023