IGF1 and NRG1 Enhance Proliferation, Metabolic Maturity, and the Force-Frequency Response in hESC-Derived Engineered Cardiac Tissues

por Rupert, Cassady E., Coulombe, Kareen L. K.
Publicado 2017

Cardiac mechanostructure: Using mechanics and anisotropy as inspiration for developing epicardial therapies in treating myocardial infarction

por Dwyer, Kiera D., Coulombe, Kareen L.K.
Publicado 2021

Stimulating Calcium Handling in hiPSC-Derived Engineered Cardiac Tissues Enhances Force Production

por Minor, Alicia J, Coulombe, Kareen L K
Publicado 2022

Practical adoption of state-of-the-art hiPSC-cardiomyocyte differentiation techniques

por Rupert, Cassady E., Irofuala, Chinedu, Coulombe, Kareen L. K.
Publicado 2020

Enhanced Electrical Integration of Engineered Human Myocardium via Intramyocardial versus Epicardial Delivery in Infarcted Rat Hearts

por Gerbin, Kaytlyn A., Yang, Xiulan, Murry, Charles E., Coulombe, Kareen L. K.
Publicado 2015

Optimizing Blended Collagen-Fibrin Hydrogels for Cardiac Tissue Engineering with Human iPSC-derived Cardiomyocytes

por Kaiser, Nicholas J., Kant, Rajeev J., Minor, Alicia J., Coulombe, Kareen L.K.
Publicado 2018

Digital Design and Automated Fabrication of Bespoke Collagen Microfiber Scaffolds

por Kaiser, Nicholas J., Bellows, Jessica A., Kant, Rajeev J., Coulombe, Kareen L.K.
Publicado 2019

Human Cardiac Fibroblast Number and Activation State Modulate Electromechanical Function of hiPSC-Cardiomyocytes in Engineered Myocardium

por Rupert, Cassady E., Kim, Tae Yun, Choi, Bum-Rak, Coulombe, Kareen L. K.
Publicado 2020

Wet-Spun Polycaprolactone Scaffolds Provide Customizable Anisotropic Viscoelastic Mechanics for Engineered Cardiac Tissues

por Schmitt, Phillip R., Dwyer, Kiera D., Minor, Alicia J., Coulombe, Kareen L. K.
Publicado 2022

Beyond Pharmaceuticals: Fit-for-Purpose New Approach Methodologies for Environmental Cardiotoxicity Testing

por Daley, Mark C., Mende, Ulrike, Choi, Bum-Rak, McMullen, Patrick D., Coulombe, Kareen L. K.
Publicado 2023

Engineering Immunomodulatory Biomaterials for Regenerating the Infarcted Myocardium

por Bloise, Nora, Rountree, Isobel, Polucha, Collin, Montagna, Giulia, Visai, Livia, Coulombe, Kareen L. K., Munarin, Fabiola
Publicado 2020

A predictive in vitro risk assessment platform for pro-arrhythmic toxicity using human 3D cardiac microtissues

por Kofron, Celinda M., Kim, Tae Yun, Munarin, Fabiola, Soepriatna, Arvin H., Kant, Rajeev J., Mende, Ulrike, Choi, Bum-Rak, Coulombe, Kareen L. K.
Publicado 2021

Patterned Arteriole-Scale Vessels Enhance Engraftment, Perfusion, and Vessel Branching Hierarchy of Engineered Human Myocardium for Heart Regeneration

por Kant, Rajeev J., Dwyer, Kiera D., Lee, Jang-Hoon, Polucha, Collin, Kobayashi, Momoka, Pyon, Stephen, Soepriatna, Arvin H., Lee, Jonghwan, Coulombe, Kareen L. K.
Publicado 2023

Action potential metrics and automated data analysis pipeline for cardiotoxicity testing using optically mapped hiPSC-derived 3D cardiac microtissues

por Soepriatna, Arvin H., Navarrete-Welton, Allison, Kim, Tae Yun, Daley, Mark C., Bronk, Peter, Kofron, Celinda M., Mende, Ulrike, Coulombe, Kareen L. K., Choi, Bum-Rak
Publicado 2023

One Billion hiPSC-Cardiomyocytes: Upscaling Engineered Cardiac Tissues to Create High Cell Density Therapies for Clinical Translation in Heart Regeneration

por Dwyer, Kiera D., Kant, Rajeev J., Soepriatna, Arvin H., Roser, Stephanie M., Daley, Mark C., Sabe, Sharif A., Xu, Cynthia M., Choi, Bum-Rak, Sellke, Frank W., Coulombe, Kareen L. K.
Publicado 2023