Quantification of spatiotemporal patterns of Ras isoform expression during development

por Newlaczyl, Anna U., Coulson, Judy M., Prior, Ian A.
Publicado 2017

RAS variant signalling

por Mo, Stephanie P., Coulson, Judy M., Prior, Ian A.
Publicado 2018

Decoding RAS isoform and codon-specific signalling

por Newlaczyl, Anna U., Hood, Fiona E., Coulson, Judy M., Prior, Ian A.
Publicado 2014

Regulation of the cell cycle and centrosome biology by deubiquitylases

por Darling, Sarah, Fielding, Andrew B., Sabat-Pośpiech, Dorota, Prior, Ian A., Coulson, Judy M.
Publicado 2017

Targeting centrosome amplification, an Achilles' heel of cancer

por Sabat-Pośpiech, Dorota, Fabian-Kolpanowicz, Kim, Prior, Ian A., Coulson, Judy M., Fielding, Andrew B.
Publicado 2019

Combinatorial approaches for mitigating resistance to KRAS-targeted therapies

por Warren, Hannah R., Ross, Sarah J., Smith, Paul D., Coulson, Judy M., Prior, Ian A.
Publicado 2022

The deubiquitylase USP15 stabilizes newly synthesized REST and rescues its expression at mitotic exit

por Faronato, Monica, Patel, Vruti, Darling, Sarah, Dearden, Laura, Clague, Michael J., Urbé, Sylvie, Coulson, Judy M.
Publicado 2013

The Chick Embryo Xenograft Model for Malignant Pleural Mesothelioma: A Cost and Time Efficient 3Rs Model for Drug Target Evaluation

por Barnett, Sarah E., Herrmann, Anne, Shaw, Liam, Gash, Elisabeth N., Poptani, Harish, Sacco, Joseph J., Coulson, Judy M.
Publicado 2022

Direct and Indirect Control of Mitogen-activated Protein Kinase Pathway-associated Components, BRAP/IMP E3 Ubiquitin Ligase and CRAF/RAF1 Kinase, by the Deubiquitylating Enzyme USP...

por Hayes, Sebastian D., Liu, Han, MacDonald, Ewan, Sanderson, Christopher M., Coulson, Judy M., Clague, Michael J., Urbé, Sylvie
Publicado 2012

Aggressive uveal melanoma displays a high degree of centrosome amplification, opening the door to therapeutic intervention

por Sabat‐Pośpiech, Dorota, Fabian‐Kolpanowicz, Kim, Kalirai, Helen, Kipling, Natalie, Coupland, Sarah E, Coulson, Judy M, Fielding, Andrew B
Publicado 2022

Loss of BAP1 expression is associated with an immunosuppressive microenvironment in uveal melanoma, with implications for immunotherapy development

por Figueiredo, Carlos R, Kalirai, Helen, Sacco, Joseph J, Azevedo, Ricardo A, Duckworth, Andrew, Slupsky, Joseph R, Coulson, Judy M, Coupland, Sarah E
Publicado 2020

Isoform-specific Ras signaling is growth factor dependent

por Hood, Fiona E., Klinger, Bertram, Newlaczyl, Anna U., Sieber, Anja, Dorel, Mathurin, Oliver, Simon P., Coulson, Judy M., Blüthgen, Nils, Prior, Ian A.
Publicado 2019

The deubiquitylase USP15 regulates topoisomerase II alpha to maintain genome integrity

por Fielding, Andrew B., Concannon, Matthew, Darling, Sarah, Rusilowicz-Jones, Emma V., Sacco, Joseph J., Prior, Ian A., Clague, Michael J., Urbé, Sylvie, Coulson, Judy M.
Publicado 2018

Loss of the deubiquitylase BAP1 alters class I histone deacetylase expression and sensitivity of mesothelioma cells to HDAC inhibitors

por Sacco, Joseph J., Kenyani, Jenna, Butt, Zohra, Carter, Rachel, Chew, Hui Yi, Cheeseman, Liam P., Darling, Sarah, Denny, Michael, Urbé, Sylvie, Clague, Michael J., Coulson, Judy M.
Publicado 2015

Patterns of BAP1 protein expression provide insights into prognostic significance and the biology of uveal melanoma

por Farquhar, Neil, Thornton, Sophie, Coupland, Sarah E, Coulson, Judy M, Sacco, Joseph J, Krishna, Yamini, Heimann, Heinrich, Taktak, Azzam, Cebulla, Colleen M, Abdel‐Rahman, Mohamed H, Kalirai, Helen
Publicado 2017

BAP1 Loss Is Associated with Higher ASS1 Expression in Epithelioid Mesothelioma: Implications for Therapeutic Stratification

por Barnett, Sarah E., Kenyani, Jenna, Tripari, Martina, Butt, Zohra, Grosman, Rudi, Querques, Francesca, Shaw, Liam, Silva, Luisa C., Goate, Zoe, Marciniak, Stefan J., Rassl, Doris M., Jackson, Richard, Lian, Lu-Yun, Szlosarek, Peter W., Sacco, Joseph J., Coulson, Judy M.
Publicado 2023

SRSF1 modulates PTPMT1 alternative splicing to regulate lung cancer cell radioresistance

por Sheng, Junxiu, Zhao, Qingzhi, Zhao, Jinyao, Zhang, Wenjing, Sun, Yu, Qin, Pan, Lv, Yuesheng, Bai, Lu, Yang, Quan, Chen, Lei, Qi, Yangfan, Zhang, Ge, Zhang, Lin, Gu, Chundong, Deng, Xiaoqin, Liu, Han, Meng, Songshu, Gu, Hong, Liu, Quentin, Coulson, Judy M., Li, Xiaoling, Sun, Bing, Wang, Yang
Publicado 2018