Solving the Evidence Interpretability Crisis in Health Technology Assessment: A Role for Mechanistic Models?

por Courcelles, Eulalie, Boissel, Jean-Pierre, Massol, Jacques, Klingmann, Ingrid, Kahoul, Riad, Hommel, Marc, Pham, Emmanuel, Kulesza, Alexander
Publicado 2022

Verifying and Validating Quantitative Systems Pharmacology and In Silico Models in Drug Development: Current Needs, Gaps, and Challenges

por Musuamba, Flora T., Bursi, Roberta, Manolis, Efthymios, Karlsson, Kristin, Kulesza, Alexander, Courcelles, Eulalie, Boissel, Jean‐Pierre, Lesage, Raphaëlle, Crozatier, Cécile, Voisin, Emmanuelle M., Rousseau, Cécile F., Marchal, Thierry, Alessandrello, Rossana, Geris, Liesbet
Publicado 2020

Scientific and regulatory evaluation of mechanistic in silico drug and disease models in drug development: Building model credibility

por Musuamba, Flora T., Skottheim Rusten, Ine, Lesage, Raphaëlle, Russo, Giulia, Bursi, Roberta, Emili, Luca, Wangorsch, Gaby, Manolis, Efthymios, Karlsson, Kristin E., Kulesza, Alexander, Courcelles, Eulalie, Boissel, Jean‐Pierre, Rousseau, Cécile F., Voisin, Emmanuelle M., Alessandrello, Rossana, Curado, Nuno, Dall’ara, Enrico, Rodriguez, Blanca, Pappalardo, Francesco, Geris, Liesbet
Publicado 2021