An Inducible Cell-Cell Fusion System with Integrated Ability to Measure the Efficiency and Specificity of HIV-1 Entry Inhibitors

por Herschhorn, Alon, Finzi, Andres, Jones, David M., Courter, Joel R., Sugawara, Akihiro, Smith, Amos B., Sodroski, Joseph G.
Publicado 2011

Contribution of Intrinsic Reactivity of the HIV-1 Envelope Glycoproteins to CD4-Independent Infection and Global Inhibitor Sensitivity

por Haim, Hillel, Strack, Bettina, Kassa, Aemro, Madani, Navid, Wang, Liping, Courter, Joel R., Princiotto, Amy, McGee, Kathleen, Pacheco, Beatriz, Seaman, Michael S., Smith, Amos B., Sodroski, Joseph
Publicado 2011

Structure-Based Design, Synthesis and Validation of CD4-Mimetic Small Molecule Inhibitors of HIV-1 Entry: Conversion of a Viral Entry Agonist to an Antagonist

por Courter, Joel R., Madani, Navid, Sodroski, Joseph, Schön, Arne, Freire, Ernesto, Kwong, Peter D., Hendrickson, Wayne A., Chaiken, Irwin M., LaLonde, Judith M., Smith, Amos B.
Publicado 2014

Crystal Structures of HIV-1 gp120 Envelope Glycoprotein in Complex with NBD Analogues That Target the CD4-Binding Site

por Kwon, Young Do, LaLonde, Judith M., Yang, Yongping, Elban, Mark A., Sugawara, Akihiro, Courter, Joel R., Jones, David M., Smith, Amos B., Debnath, Asim K., Kwong, Peter D.
Publicado 2014

Soluble CD4 and CD4-Mimetic Compounds Inhibit HIV-1 Infection by Induction of a Short-Lived Activated State

por Haim, Hillel, Si, Zhihai, Madani, Navid, Wang, Liping, Courter, Joel R., Princiotto, Amy, Kassa, Aemro, DeGrace, Marciella, McGee-Estrada, Kathleen, Mefford, Megan, Gabuzda, Dana, Smith, Amos B., Sodroski, Joseph
Publicado 2009

Small CD4 Mimetics Prevent HIV-1 Uninfected Bystander CD4 + T Cell Killing Mediated by Antibody-dependent Cell-mediated Cytotoxicity

por Richard, Jonathan, Veillette, Maxime, Ding, Shilei, Zoubchenok, Daria, Alsahafi, Nirmin, Coutu, Mathieu, Brassard, Nathalie, Park, Jongwoo, Courter, Joel R., Melillo, Bruno, Smith, Amos B., Shaw, George M., Hahn, Beatrice H., Sodroski, Joseph, Kaufmann, Daniel E., Finzi, Andrés
Publicado 2015

Co-receptor Binding Site Antibodies Enable CD4-Mimetics to Expose Conserved Anti-cluster A ADCC Epitopes on HIV-1 Envelope Glycoproteins

por Richard, Jonathan, Pacheco, Beatriz, Gohain, Neelakshi, Veillette, Maxime, Ding, Shilei, Alsahafi, Nirmin, Tolbert, William D., Prévost, Jérémie, Chapleau, Jean-Philippe, Coutu, Mathieu, Jia, Manxue, Brassard, Nathalie, Park, Jongwoo, Courter, Joel R., Melillo, Bruno, Martin, Loïc, Tremblay, Cécile, Hahn, Beatrice H., Kaufmann, Daniel E., Wu, Xueling, Smith, Amos B., Sodroski, Joseph, Pazgier, Marzena, Finzi, Andrés
Publicado 2016