Akt Inhibition Promotes ABCA1-Mediated Cholesterol Efflux to ApoA-I through Suppressing mTORC1

por Dong, Fumin, Mo, Zhongcheng, Eid, Walaa, Courtney, Kevin C., Zha, Xiaohui
Publicado 2014

Resolving kinetic intermediates during the regulated assembly and disassembly of fusion pores

por Das, Debasis, Bao, Huan, Courtney, Kevin C., Wu, Lanxi, Chapman, Edwin R.
Publicado 2020

Comment on ‘Orthogonal lipid sensors identify transbilayer asymmetry of plasma membrane cholesterol’

por Courtney, Kevin C, Fung, Karen YY, Maxfield, Frederick R, Fairn, Gregory D, Zha, Xiaohui
Publicado 2018

Synaptotagmin 1 oligomerization via the juxtamembrane linker regulates spontaneous and evoked neurotransmitter release

por Courtney, Kevin C., Vevea, Jason D., Li, Yueqi, Wu, Zhenyong, Zhang, Zhao, Chapman, Edwin R.
Publicado 2021

Synaptotagmin 7 is targeted to the axonal plasma membrane through γ-secretase processing to promote synaptic vesicle docking in mouse hippocampal neurons

por Vevea, Jason D, Kusick, Grant F, Courtney, Kevin C, Chen, Erin, Watanabe, Shigeki, Chapman, Edwin R
Publicado 2021

Synaptotagmin-7 outperforms synaptotagmin-1 to promote the formation of large, stable fusion pores via robust membrane penetration

por Courtney, Kevin C., Mandal, Taraknath, Mehta, Nikunj, Wu, Lanxi, Li, Yueqi, Das, Debasis, Cui, Qiang, Chapman, Edwin R.
Publicado 2023

Beyond Amphiphilic Balance: Changing Subunit Stereochemistry Alters the Pore-Forming Activity of Nylon-3 Polymers

por Liu, Lei, Courtney, Kevin C., Huth, Sean W., Rank, Leslie A., Weisblum, Bernard, Chapman, Edwin R., Gellman, Samuel H.
Publicado 2021