The anti-inflammatory and immunosuppressive effects of glucocorticoids, recent developments and mechanistic insights

por Coutinho, Agnes E., Chapman, Karen E.
Publicado 2011

Changing glucocorticoid action: 11β-Hydroxysteroid dehydrogenase type 1 in acute and chronic inflammation

por Chapman, Karen E., Coutinho, Agnes E., Zhang, Zhenguang, Kipari, Tiina, Savill, John S., Seckl, Jonathan R.
Publicado 2013

Mast Cells Express 11β-hydroxysteroid Dehydrogenase Type 1: A Role in Restraining Mast Cell Degranulation

por Coutinho, Agnes E., Brown, Jeremy K., Yang, Fu, Brownstein, David G., Gray, Mohini, Seckl, Jonathan R., Savill, John S., Chapman, Karen E.
Publicado 2013

Macrophage 11β-HSD-1 deficiency promotes inflammatory angiogenesis

por Zhang, Zhenguang, Coutinho, Agnes E, Man, Tak Yung, Kipari, Tiina M J, Hadoke, Patrick W F, Salter, Donald M, Seckl, Jonathan R, Chapman, Karen E
Publicado 2017

11β-Hydroxysteroid Dehydrogenase Type 1, But Not Type 2, Deficiency Worsens Acute Inflammation and Experimental Arthritis in Mice

por Coutinho, Agnes E., Gray, Mohini, Brownstein, David G., Salter, Donald M., Sawatzky, Deborah A., Clay, Spike, Gilmour, James S., Seckl, Jonathan R., Savill, John S., Chapman, Karen E.
Publicado 2012

11β-Hydroxysteroid Dehydrogenase Type 1 Is Expressed in Neutrophils and Restrains an Inflammatory Response in Male Mice

por Coutinho, Agnes E., Kipari, Tiina M. J., Zhang, Zhenguang, Esteves, Cristina L., Lucas, Christopher D., Gilmour, James S., Webster, Scott P., Walker, Brian R., Hughes, Jeremy, Savill, John S., Seckl, Jonathan R., Rossi, Adriano G., Chapman, Karen E.
Publicado 2016

11β-hydroxysteroid dehydrogenase type 1 deficiency in bone marrow-derived cells reduces atherosclerosis

por Kipari, Tiina, Hadoke, Patrick W. F., Iqbal, Javaid, Man, Tak-Yung, Miller, Eileen, Coutinho, Agnes E., Zhang, Zhenguang, Sullivan, Katie M., Mitic, Tijana, Livingstone, Dawn E. W., Schrecker, Christopher, Samuel, Kay, White, Christopher I., Bouhlel, M. Amine, Chinetti-Gbaguidi, Giulia, Staels, Bart, Andrew, Ruth, Walker, Brian R., Savill, John S., Chapman, Karen E., Seckl, Jonathan R.
Publicado 2013