A molecular map of long non-coding RNA expression, isoform switching and alternative splicing in osteoarthritis

por Katsoula, Georgia, Steinberg, Julia, Tuerlings, Margo, Coutinho de Almeida, Rodrigo, Southam, Lorraine, Swift, Diane, Meulenbelt, Ingrid, Wilkinson, J Mark, Zeggini, Eleftheria
Publicado 2022

Circulating MicroRNAs Highly Correlate to Expression of Cartilage Genes Potentially Reflecting OA Susceptibility—Towards Identification of Applicable Early OA Biomarkers

por Ramos, Yolande F. M., Coutinho de Almeida, Rodrigo, Lakenberg, Nico, Suchiman, Eka, Mei, Hailiang, Kloppenburg, Margreet, Nelissen, Rob G. H. H., Meulenbelt, Ingrid
Publicado 2021

Allelic expression imbalance in articular cartilage and subchondral bone refined genome-wide association signals in osteoarthritis

por Coutinho de Almeida, Rodrigo, Tuerlings, Margo, Ramos, Yolande, Den Hollander, Wouter, Suchiman, Eka, Lakenberg, Nico, Nelissen, Rob G H H, Mei, Hailiang, Meulenbelt, Ingrid
Publicado 2022

A Combined mRNA- and miRNA-Sequencing Approach Reveals miRNAs as Potential Regulators of the Small Intestinal Transcriptome in Celiac Disease

por Tan, Ineke Luise, Barisani, Donatella, Panceri, Roberto, Modderman, Rutger, Visschedijk, Marijn, Weersma, Rinse K., Wijmenga, Cisca, Jonkers, Iris, Coutinho de Almeida, Rodrigo, Withoff, Sebo
Publicado 2021

An epigenome-wide view of osteoarthritis in primary tissues

por Kreitmaier, Peter, Suderman, Matthew, Southam, Lorraine, Coutinho de Almeida, Rodrigo, Hatzikotoulas, Konstantinos, Meulenbelt, Ingrid, Steinberg, Julia, Relton, Caroline L., Wilkinson, J. Mark, Zeggini, Eleftheria
Publicado 2022

The role of TNFRSF11B in development of osteoarthritic cartilage

por Rodríguez Ruiz, Alejandro, Tuerlings, Margo, Das, Ankita, Coutinho de Almeida, Rodrigo, Suchiman, H Eka D, Nelissen, Rob G H H, Ramos, Yolande F M, Meulenbelt, Ingrid
Publicado 2021

Elucidating mechano-pathology of osteoarthritis: transcriptome-wide differences in mechanically stressed aged human cartilage explants

por Houtman, Evelyn, Tuerlings, Margo, Riechelman, Janne, Suchiman, Eka H. E. D., van der Wal, Robert J. P., Nelissen, Rob G. H. H., Mei, Hailiang, Ramos, Yolande F. M., Coutinho de Almeida, Rodrigo, Meulenbelt, Ingrid
Publicado 2021

Identification and characterization of two consistent osteoarthritis subtypes by transcriptome and clinical data integration

por Coutinho de Almeida, Rodrigo, Mahfouz, Ahmed, Mei, Hailiang, Houtman, Evelyn, den Hollander, Wouter, Soul, Jamie, Suchiman, Eka, Lakenberg, Nico, Meessen, Jennifer, Huetink, Kasper, Nelissen, Rob G H H, Ramos, Yolande F M, Reinders, Marcel, Meulenbelt, Ingrid
Publicado 2020

Long non-coding RNA expression profiling of subchondral bone reveals AC005165.1 modifying FRZB expression during osteoarthritis

por Tuerlings, Margo, van Hoolwerff, Marcella, van Bokkum, Jessica M, Suchiman, H Eka D, Lakenberg, Nico, Broekhuis, Demiën, Nelissen, Rob G H H, Ramos, Yolande F M, Mei, Hailiang, Cats, Davy, Coutinho de Almeida, Rodrigo, Meulenbelt, Ingrid
Publicado 2021

Inhibiting thyroid activation in aged human explants prevents mechanical induced detrimental signalling by mitigating metabolic processes

por Houtman, Evelyn, Tuerlings, Margo, Suchiman, H Eka D, Lakenberg, Nico, Cornelis, Frederique M F, Mei, Hailiang, Broekhuis, Demiën, Nelissen, Rob G H H, Coutinho de Almeida, Rodrigo, Ramos, Yolande F M, Lories, Rik J, Cruz, Luis J, Meulenbelt, Ingrid
Publicado 2022

RNA Sequencing Reveals Interacting Key Determinants of Osteoarthritis Acting in Subchondral Bone and Articular Cartilage: Identification of IL11 and CHADL as Attractive Treatment T...

por Tuerlings, Margo, van Hoolwerff, Marcella, Houtman, Evelyn, Suchiman, Eka H. E. D., Lakenberg, Nico, Mei, Hailiang, van der Linden, Enrike H. M. J., Nelissen, Rob R. G. H. H., Ramos, Yolande Y. F. M., Coutinho de Almeida, Rodrigo, Meulenbelt, Ingrid
Publicado 2021

Identification and functional characterization of imbalanced osteoarthritis-associated fibronectin splice variants

por van Hoolwerff, Marcella, Tuerlings, Margo, Wijnen, Imke J L, Suchiman, H Eka D, Cats, Davy, Mei, Hailiang, Nelissen, Rob G H H, van der Linden–van der Zwaag, Henrike M J, Ramos, Yolande F M, Coutinho de Almeida, Rodrigo, Meulenbelt, Ingrid
Publicado 2022

Genome-wide association of phenotypes based on clustering patterns of hand osteoarthritis identify WNT9A as novel osteoarthritis gene

por Boer, Cindy Germaine, Yau, Michelle S, Rice, Sarah J, Coutinho de Almeida, Rodrigo, Cheung, Kathleen, Styrkarsdottir, Unnur, Southam, Lorraine, Broer, Linda, Wilkinson, Jeremy Mark, Uitterlinden, André G, Zeggini, Eleftheria, Felson, David, Loughlin, John, Young, Mariel, Capellini, Terence Dante, Meulenbelt, Ingrid, van Meurs, Joyce BJ
Publicado 2021

RNA sequencing data integration reveals an miRNA interactome of osteoarthritis cartilage

por Coutinho de Almeida, Rodrigo, Ramos, Yolande F M, Mahfouz, Ahmed, den Hollander, Wouter, Lakenberg, Nico, Houtman, Evelyn, van Hoolwerff, Marcella, Suchiman, H Eka D, Rodríguez Ruiz, Alejandro, Slagboom, P Eline, Mei, Hailiang, Kiełbasa, Szymon M, Nelissen, Rob G H H, Reinders, Marcel, Meulenbelt, Ingrid
Publicado 2019

Circulating miRNAs as Potential Biomarkers for Celiac Disease Development

por Tan, Ineke L., Coutinho de Almeida, Rodrigo, Modderman, Rutger, Stachurska, Anna, Dekens, Jackie, Barisani, Donatella, Meijer, Caroline R., Roca, María, Martinez-Ojinaga, Eva, Shamir, Raanan, Auricchio, Renata, Korponay-Szabó, Ilma R., Castillejo, Gemma, Szajewska, Hania, Koletzko, Sibylle, Zhernakova, Alexandra, Kumar, Vinod, Li, Yang, Visschedijk, Marijn C., Weersma, Rinse K., Troncone, Riccardo, Mearin, M. Luisa, Wijmenga, Cisca, Jonkers, Iris, Withoff, Sebo
Publicado 2021

Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations

por Boer, Cindy G., Hatzikotoulas, Konstantinos, Southam, Lorraine, Stefánsdóttir, Lilja, Zhang, Yanfei, Coutinho de Almeida, Rodrigo, Wu, Tian T., Zheng, Jie, Hartley, April, Teder-Laving, Maris, Skogholt, Anne Heidi, Terao, Chikashi, Zengini, Eleni, Alexiadis, George, Barysenka, Andrei, Bjornsdottir, Gyda, Gabrielsen, Maiken E., Gilly, Arthur, Ingvarsson, Thorvaldur, Johnsen, Marianne B., Jonsson, Helgi, Kloppenburg, Margreet, Luetge, Almut, Lund, Sigrun H., Mägi, Reedik, Mangino, Massimo, Nelissen, Rob R.G.H.H., Shivakumar, Manu, Steinberg, Julia, Takuwa, Hiroshi, Thomas, Laurent F., Tuerlings, Margo, Babis, George C., Cheung, Jason Pui Yin, Kang, Jae Hee, Kraft, Peter, Lietman, Steven A., Samartzis, Dino, Slagboom, P. Eline, Stefansson, Kari, Thorsteinsdottir, Unnur, Tobias, Jonathan H., Uitterlinden, André G., Winsvold, Bendik, Zwart, John-Anker, Davey Smith, George, Sham, Pak Chung, Thorleifsson, Gudmar, Gaunt, Tom R., Morris, Andrew P., Valdes, Ana M., Tsezou, Aspasia, Cheah, Kathryn S.E., Ikegawa, Shiro, Hveem, Kristian, Esko, Tõnu, Wilkinson, J. Mark, Meulenbelt, Ingrid, Lee, Ming Ta Michael, van Meurs, Joyce B.J., Styrkársdóttir, Unnur, Zeggini, Eleftheria
Publicado 2021

Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations

por Boer, Cindy G., Hatzikotoulas, Konstantinos, Southam, Lorraine, Stefánsdóttir, Lilja, Zhang, Yanfei, Coutinho de Almeida, Rodrigo, Wu, Tian T., Zheng, Jie, Hartley, April, Teder-Laving, Maris, Skogholt, Anne Heidi, Terao, Chikashi, Zengini, Eleni, Alexiadis, George, Barysenka, Andrei, Bjornsdottir, Gyda, Gabrielsen, Maiken E., Gilly, Arthur, Ingvarsson, Thorvaldur, Johnsen, Marianne B., Jonsson, Helgi, Kloppenburg, Margreet, Luetge, Almut, Lund, Sigrun H., Mägi, Reedik, Mangino, Massimo, Nelissen, Rob R.G.H.H., Shivakumar, Manu, Steinberg, Julia, Takuwa, Hiroshi, Thomas, Laurent F., Tuerlings, Margo, Babis, George C., Yin Cheung, Jason Pui, Kang, Jae Hee, Kraft, Peter, Lietman, Steven A., Samartzis, Dino, Slagboom, P. Eline, Stefansson, Kari, Thorsteinsdottir, Unnur, Tobias, Jonathan H., Uitterlinden, André G., Winsvold, Bendik, Zwart, John-Anker, Smith, George Davey, Sham, Pak Chung, Thorleifsson, Gudmar, Gaunt, Tom R., Morris, Andrew P., Valdes, Ana M., Tsezou, Aspasia, Cheah, Kathryn S.E., Ikegawa, Shiro, Hveem, Kristian, Esko, Tõnu, Wilkinson, J. Mark, Meulenbelt, Ingrid, Michael Lee, Ming Ta, van Meurs, Joyce B.J., Styrkársdóttir, Unnur, Zeggini, Eleftheria
Publicado 2021