Three interrelated themes in current breast cancer research: gene addiction, phenotypic plasticity, and cancer stem cells

por Cardiff, Robert D, Couto, Suzana, Bolon, Brad
Publicado 2011

MYC Cooperates with AKT in Prostate Tumorigenesis and Alters Sensitivity to mTOR Inhibitors

por Clegg, Nicola J., Couto, Suzana S., Wongvipat, John, Hieronymus, Haley, Carver, Brett S., Taylor, Barry S., Ellwood-Yen, Katharine, Gerald, William L., Sander, Chris, Sawyers, Charles L.
Publicado 2011

Host genetic background impacts modulation of the TLR4 pathway by RON in tissue-associated macrophages

por Chaudhuri, Amitabha, Wilson, Nicholas S, Yang, Becky, Paler Martinez, Andres, Liu, Jinfeng, Zhu, Catherine, Bricker, Nicole, Couto, Suzana, Modrusan, Zora, French, Dorothy, Cupp, James, Ashkenazi, Avi
Publicado 2013

A Dual Color Immunohistochemistry Assay for Measurement of Cereblon in Multiple Myeloma Patient Samples

por Ren, Yan, Wang, Maria, Couto, Suzana, Hansel, Donna E., Miller, Karen, Lopez-Girona, Antonia, Bjorklund, Chad C., Gandhi, Anita K., Thakurta, Anjan, Chopra, Rajesh, Breider, Michael
Publicado 2016

Iberdomide (CC-220) is a potent cereblon E3 ligase modulator with antitumor and immunostimulatory activities in lenalidomide- and pomalidomide-resistant multiple myeloma cells with...

por Bjorklund, Chad C., Kang, Jian, Amatangelo, Michael, Polonskaia, Ann, Katz, Mark, Chiu, Hsiling, Couto, Suzana, Wang, Maria, Ren, Yan, Ortiz, Maria, Towfic, Fadi, Flynt, J. Erin, Pierceall, William, Thakurta, Anjan
Publicado 2019

ISCOMATRIX vaccines mediate CD8(+) T-cell cross-priming by a MyD88-dependent signaling pathway

por Wilson, Nicholas S, Yang, Becky, Morelli, Adriana Baz, Koernig, Sandra, Yang, Annie, Loeser, Stefanie, Airey, Denise, Provan, Larissa, Hass, Phil, Braley, Hal, Couto, Suzana, Drane, Debbie, Boyle, Jeff, Belz, Gabrielle T, Ashkenazi, Avi, Maraskovsky, Eugene
Publicado 2012

UBE2G1 governs the destruction of cereblon neomorphic substrates

por Lu, Gang, Weng, Stephanie, Matyskiela, Mary, Zheng, Xinde, Fang, Wei, Wood, Scott, Surka, Christine, Mizukoshi, Reina, Lu, Chin-Chun, Mendy, Derek, Jang, In Sock, Wang, Kai, Marella, Mathieu, Couto, Suzana, Cathers, Brian, Carmichael, James, Chamberlain, Philip, Rolfe, Mark
Publicado 2018

Targeting the Wnt signaling pathway through R-spondin 3 identifies an anti-fibrosis treatment strategy for multiple organs

por Zhang, Mingjun, Haughey, Michael, Wang, Nai-Yu, Blease, Kate, Kapoun, Ann M., Couto, Suzana, Belka, Igor, Hoey, Timothy, Groza, Matthew, Hartke, James, Bennett, Brydon, Cain, Jennifer, Gurney, Austin, Benish, Brent, Castiglioni, Paola, Drew, Clifton, Lachowicz, Jean, Carayannopoulos, Leon, Nathan, Steven D., Distler, Jorg, Brenner, David A., Hariharan, Kandasamy, Cho, Ho, Xie, Weilin
Publicado 2020

Bone marrow microenvironments that contribute to patient outcomes in newly diagnosed multiple myeloma: A cohort study of patients in the Total Therapy clinical trials

por Danziger, Samuel A., McConnell, Mark, Gockley, Jake, Young, Mary H., Rosenthal, Adam, Schmitz, Frank, Reiss, David J., Farmer, Phil, Alapat, Daisy V., Singh, Amrit, Ashby, Cody, Bauer, Michael, Ren, Yan, Smith, Kelsie, Couto, Suzana S., van Rhee, Frits, Davies, Faith, Zangari, Maurizio, Petty, Nathan, Orlowski, Robert Z., Dhodapkar, Madhav V., Copeland, Wilbert B., Fox, Brian, Hoering, Antje, Fitch, Alison, Newhall, Katie, Barlogie, Bart, Trotter, Matthew W. B., Hershberg, Robert M., Walker, Brian A., Dervan, Andrew P., Ratushny, Alexander V., Morgan, Gareth J.
Publicado 2020