Mitochondrial DNA variants segregate during human preimplantation development into genetically different cell lineages that are maintained postnatally

por Mertens, Joke, Regin, Marius, De Munck, Neelke, Couvreu de Deckersberg, Edouard, Belva, Florence, Sermon, Karen, Tournaye, Herman, Blockeel, Christophe, Van de Velde, Hilde, Spits, Claudia
Publicado 2022

Myotonic dystrophy type 1 embryonic stem cells show decreased myogenic potential, increased CpG methylation at the DMPK locus and RNA mis-splicing

por Franck, Silvie, Couvreu De Deckersberg, Edouard, Bubenik, Jodi L., Markouli, Christina, Barbé, Lise, Allemeersch, Joke, Hilven, Pierre, Duqué, Geoffrey, Swanson, Maurice S., Gheldof, Alexander, Spits, Claudia, Karen, D.
Publicado 2022

Endogenous suppression of WNT signalling in human embryonic stem cells leads to low differentiation propensity towards definitive endoderm

por Dziedzicka, Dominika, Tewary, Mukul, Keller, Alexander, Tilleman, Laurentijn, Prochazka, Laura, Östblom, Joel, Couvreu De Deckersberg, Edouard, Markouli, Christina, Franck, Silvie, Van Nieuwerburgh, Filip, Spits, Claudia, Zandstra, Peter W., Sermon, Karen, Geens, Mieke
Publicado 2021