Whole-cell modeling of E. coli confirms that in vitro tRNA aminoacylation measurements are insufficient to support cell growth and predicts a positive feedback mechanism regulating...

por Choi, Heejo, Covert, Markus W
Publicado 2023

Combining Comprehensive Analysis of Off-Site Lambda Phage Integration with a CRISPR-Based Means of Characterizing Downstream Physiology

por Tanouchi, Yu, Covert, Markus W.
Publicado 2017

Techniques for Studying Decoding of Single Cell Dynamics

por Jeknić, Stevan, Kudo, Takamasa, Covert, Markus W.
Publicado 2019

WholeCellViz: data visualization for whole-cell models

por Lee, Ruby, Karr, Jonathan R, Covert, Markus W
Publicado 2013

A Protocol to Engineer Bacteriophages for Live-Cell Imaging of Bacterial Prophage Induction Inside Mammalian Cells

por Bodner, Katie, Melkonian, Arin L., Covert, Markus W.
Publicado 2020

Determining Host Metabolic Limitations on Viral Replication via Integrated Modeling and Experimental Perturbation

por Birch, Elsa W., Ruggero, Nicholas A., Covert, Markus W.
Publicado 2012

WholeCellSimDB: a hybrid relational/HDF database for whole-cell model predictions

por Karr, Jonathan R., Phillips, Nolan C., Covert, Markus W.
Publicado 2014

Competing pathways control host resistance to virus via tRNA modification and programmed ribosomal frameshifting

por Maynard, Nathaniel D, Macklin, Derek N, Kirkegaard, Karla, Covert, Markus W
Publicado 2012

Single-cell variation leads to population invariance in NF-κB signaling dynamics

por Hughey, Jacob J., Gutschow, Miriam V., Bajar, Bryce T., Covert, Markus W.
Publicado 2015

A dynamic network of transcription in LPS-treated human subjects

por Seok, Junhee, Xiao, Wenzhong, Moldawer, Lyle L, Davis, Ronald W, Covert, Markus W
Publicado 2009

WholeCellKB: model organism databases for comprehensive whole-cell models

por Karr, Jonathan R., Sanghvi, Jayodita C., Macklin, Derek N., Arora, Abhishek, Covert, Markus W.
Publicado 2013

An expanded whole-cell model of E. coli links cellular physiology with mechanisms of growth rate control

por Ahn-Horst, Travis A., Mille, Luis Santiago, Sun, Gwanggyu, Morrison, Jerry H., Covert, Markus W.
Publicado 2022

A Forward-Genetic Screen and Dynamic Analysis of Lambda Phage Host-Dependencies Reveals an Extensive Interaction Network and a New Anti-Viral Strategy

por Maynard, Nathaniel D., Birch, Elsa W., Sanghvi, Jayodita C., Chen, Lu, Gutschow, Miriam V., Covert, Markus W.
Publicado 2010

Single-Cell and Population NF-κB Dynamic Responses Depend on Lipopolysaccharide Preparation

por Gutschow, Miriam V., Hughey, Jacob J., Ruggero, Nicholas A., Bajar, Bryce T., Valle, Sean D., Covert, Markus W.
Publicado 2013

Accelerated discovery via a whole-cell model

por Sanghvi, Jayodita C., Regot, Sergi, Carrasco, Silvia, Karr, Jonathan R., Gutschow, Miriam V., Bolival, Benjamin, Covert, Markus W.
Publicado 2013

NetworkPainter: dynamic intracellular pathway animation in Cytobank

por Karr, Jonathan R, Guturu, Harendra, Chen, Edward Y, Blair, Stuart L, Irish, Jonathan M, Kotecha, Nikesh, Covert, Markus W
Publicado 2015

Combinatorial processing of bacterial and host-derived innate immune stimuli at the single-cell level

por Gutschow, Miriam V., Mason, John C., Lane, Keara M., Maayan, Inbal, Hughey, Jacob J., Bajar, Bryce T., Amatya, Debha N., Valle, Sean D., Covert, Markus W.
Publicado 2019

Whole-cell modeling of E. coli colonies enables quantification of single-cell heterogeneity in antibiotic responses

por Skalnik, Christopher J., Cheah, Sean Y., Yang, Mica Y., Wolff, Mattheus B., Spangler, Ryan K., Talman, Lee, Morrison, Jerry H., Peirce, Shayn M., Agmon, Eran, Covert, Markus W.
Publicado 2023

Deep Learning Automates the Quantitative Analysis of Individual Cells in Live-Cell Imaging Experiments

por Van Valen, David A., Kudo, Takamasa, Lane, Keara M., Macklin, Derek N., Quach, Nicolas T., DeFelice, Mialy M., Maayan, Inbal, Tanouchi, Yu, Ashley, Euan A., Covert, Markus W.
Publicado 2016

High-resolution imaging and computational analysis of haematopoietic cell dynamics in vivo

por Koechlein, Claire S., Harris, Jeffrey R., Lee, Timothy K., Weeks, Joi, Fox, Raymond G., Zimdahl, Bryan, Ito, Takahiro, Blevins, Allen, Jung, Seung-Hye, Chute, John P., Chourasia, Amit, Covert, Markus W., Reya, Tannishtha
Publicado 2016