Neurosteroid Modulation of GABA(A) Receptor Function by Independent Action at Multiple Specific Binding Sites

por Wang, Lei, Covey, Douglas F., Akk, Gustav, Evers, Alex S.
Publicado 2022

Synthesis of a Smoothened Cholesterol: 18,19-Di-nor-cholesterol

por Mydock-McGrane, Laurel, Rath, Nigam P., Covey, Douglas F.
Publicado 2014

Correction to Synthesis of a Smoothened Cholesterol: 18,19-Di-nor-cholesterol

por Mydock-McGrane, Laurel, Rath, Nigam P., Covey, Douglas F.
Publicado 2015

Neurosteroids as novel antidepressants and anxiolytics: GABA-A receptors and beyond

por Zorumski, Charles F., Paul, Steven M., Covey, Douglas F., Mennerick, Steven
Publicado 2019

Additive neuroprotective effects of 24(S)-hydroxycholesterol and allopregnanolone in an ex vivo rat glaucoma model

por Ishikawa, Makoto, Yoshitomi, Takeshi, Covey, Douglas F., Zorumski, Charles F., Izumi, Yukitoshi
Publicado 2018

Neurosteroids in Pain Management: A New Perspective on an Old Player

por Joksimovic, Sonja L., Covey, Douglas F., Jevtovic-Todorovic, Vesna, Todorovic, Slobodan M.
Publicado 2018

Enantioselective Protein-Sterol Interactions Mediate Regulation of Both Prokaryotic and Eukaryotic Inward Rectifier K(+) Channels by Cholesterol

por D'Avanzo, Nazzareno, Hyrc, Krzysztof, Enkvetchakul, Decha, Covey, Douglas F., Nichols, Colin G.
Publicado 2011

Cholesterol Tuning of BK Ethanol Response Is Enantioselective, and Is a Function of Accompanying Lipids

por Yuan, Chunbo, Chen, Maohui, Covey, Douglas F., Johnston, Linda J., Treistman, Steven N.
Publicado 2011

Kinetic and Structural Determinants for GABA-A Receptor Potentiation by Neuroactive Steroids

por Akk, Gustav, Covey, Douglas F., Evers, Alex S., Mennerick, Steven, Zorumski, Charles F., Steinbach, Joe Henry
Publicado 2010

General Anesthesia and the Young Brain: The Importance of Novel Strategies with Alternate Mechanisms of Action

por Maksimovic, Stefan, Useinovic, Nemanja, Quillinan, Nidia, Covey, Douglas F., Todorovic, Slobodan M., Jevtovic-Todorovic, Vesna
Publicado 2022

Neurosteroids as stress modulators and neurotherapeutics: lessons from the retina

por Izumi, Yukitoshi, Ishikawa, Makoto, Nakazawa, Toru, Kunikata, Hiroshi, Sato, Kota, Covey, Douglas F., Zorumski, Charles F.
Publicado 2022

Oxidative stress in NPC1 deficient cells: protective effect of allopregnanolone

por Zampieri, Stefania, Mellon, Synthia H, Butters, Terry D, Nevyjel, Marco, Covey, Douglas F, Bembi, Bruno, Dardis, Andrea
Publicado 2009

Oxysterols are allosteric activators of the oncoprotein Smoothened

por Nachtergaele, Sigrid, Mydock, Laurel K., Krishnan, Kathiresan, Rammohan, Jayan, Schlesinger, Paul H., Covey, Douglas F., Rohatgi, Rajat
Publicado 2012

A Clickable Oxysterol Photolabel Retains NMDA Receptor Activity and Accumulates in Neurons

por Chen, Daniel M., Ziolkowski, Luke, Benz, Ann, Qian, Mingxing, Zorumski, Charles F., Covey, Douglas F., Mennerick, Steven
Publicado 2018

Preemptive Analgesic Effect of Intrathecal Applications of Neuroactive Steroids in a Rodent Model of Post-Surgical Pain: Evidence for the Role of T-Type Calcium Channels

por Tat, Quy L., Joksimovic, Srdjan M., Krishnan, Kathiresan, Covey, Douglas F., Todorovic, Slobodan M., Jevtovic-Todorovic, Vesna
Publicado 2020

Quantitative imaging of membrane contact sites for sterol transfer between endo-lysosomes and mitochondria in living cells

por Juhl, Alice Dupont, Heegaard, Christian W., Werner, Stephan, Schneider, Gerd, Krishnan, Kathiresan, Covey, Douglas F., Wüstner, Daniel
Publicado 2021

Differential effects of the novel neurosteroid hypnotic (3β,5β,17β)-3-hydroxyandrostane-17-carbonitrile on electroencephalogram activity in male and female rats

por Joksimovic, Srdjan M., Sampath, Dayalan, Krishnan, Kathiresan, Covey, Douglas F., Jevtovic-Todorovic, Vesna, Raol, Yogendra H., Todorovic, Slobodan M.
Publicado 2021

Further Evidence that Inhibition of Neuronal Voltage-Gated Calcium Channels Contributes to the Hypnotic Effect of Neurosteroid Analogue, 3β-OH

por Timic Stamenic, Tamara, Manzella, Francesca M., Maksimovic, Stefan, Krishnan, Kathiresan, Covey, Douglas F., Jevtovic-Todorovic, Vesna, Todorovic, Slobodan M.
Publicado 2022

Eliminating the Roughness in Cholesterol’s β-Face: Does it Matter?

por Krause, Martin R., Wang, Minghui, Mydock-McGrane, Laurel, Covey, Douglas F., Tejada, Emmanuel, Almeida, Paulo F., Regen, Steven L.
Publicado 2014

The Enantiomer of Allopregnanolone Prevents Pressure-Mediated Retinal Degeneration Via Autophagy

por Ishikawa, Makoto, Nakazawa, Toru, Kunikata, Hiroshi, Sato, Kota, Yoshitomi, Takeshi, Krishnan, Kathiresan, Covey, Douglas F., Zorumski, Charles F., Izumi, Yukitoshi
Publicado 2022