Exploration of the Plasmodium falciparum Resistome and Druggable Genome Reveals New Mechanisms of Drug Resistance and Antimalarial Targets

por Cowell, Annie, Winzeler, Elizabeth
Publicado 2018

2537. #IDDailyPearl: A Twitter Tool to Enhance Literature Engagement on Busy Infectious Diseases Consult Services

por Cowell, Annie N, Wooten, Darcy
Publicado 2019

Advances in omics-based methods to identify novel targets for malaria and other parasitic protozoan infections

por Cowell, Annie N., Winzeler, Elizabeth A.
Publicado 2019

The genomic architecture of antimalarial drug resistance

por Cowell, Annie N, Winzeler, Elizabeth A
Publicado 2019

Exploration of Plasmodium vivax transmission dynamics and recurrent infections in the Peruvian Amazon using whole genome sequencing

por Cowell, Annie N., Valdivia, Hugo O., Bishop, Danett K., Winzeler, Elizabeth A.
Publicado 2018

Whole-genome surveillance identifies markers of Plasmodium falciparum drug resistance and novel genomic regions under selection in Mozambique

por Coonahan, Erin, Gage, Hunter, Chen, Daisy, Noormahomed, Emilia Virginia, Buene, Titos Paulo, Mendes de Sousa, Irina, Akrami, Kevan, Chambal, Lucia, Schooley, Robert T., Winzeler, Elizabeth A., Cowell, Annie N.
Publicado 2023

Selective Whole-Genome Amplification Is a Robust Method That Enables Scalable Whole-Genome Sequencing of Plasmodium vivax from Unprocessed Clinical Samples

por Cowell, Annie N., Loy, Dorothy E., Sundararaman, Sesh A., Valdivia, Hugo, Fisch, Kathleen, Lescano, Andres G., Baldeviano, G. Christian, Durand, Salomon, Gerbasi, Vince, Sutherland, Colin J., Nolder, Debbie, Vinetz, Joseph M., Hahn, Beatrice H., Winzeler, Elizabeth A.
Publicado 2017

A Variant PfCRT Isoform Can Contribute to Plasmodium falciparum Resistance to the First-Line Partner Drug Piperaquine

por Dhingra, Satish K., Redhi, Devasha, Combrinck, Jill M., Yeo, Tomas, Okombo, John, Henrich, Philipp P., Cowell, Annie N., Gupta, Purva, Stegman, Matthew L., Hoke, Jonathan M., Cooper, Roland A., Winzeler, Elizabeth, Mok, Sachel, Egan, Timothy J., Fidock, David A.
Publicado 2017

Dual RNA-seq identifies human mucosal immunity protein Mucin-13 as a hallmark of Plasmodium exoerythrocytic infection

por LaMonte, Gregory M., Orjuela-Sanchez, Pamela, Calla, Jaeson, Wang, Lawrence T., Li, Shangzhong, Swann, Justine, Cowell, Annie N., Zou, Bing Yu, Abdel-Haleem Mohamed, Alyaa M., Villa Galarce, Zaira Hellen, Moreno, Marta, Tong Rios, Carlos, Vinetz, Joseph M., Lewis, Nathan, Winzeler, Elizabeth A.
Publicado 2019

The Key Glycolytic Enzyme Phosphofructokinase Is Involved in Resistance to Antiplasmodial Glycosides

por Fisher, Gillian M., Cobbold, Simon A., Jezewski, Andrew, Carpenter, Emma F., Arnold, Megan, Cowell, Annie N., Tjhin, Erick T., Saliba, Kevin J., Skinner-Adams, Tina S., Lee, Marcus C. S., Odom John, Audrey, Winzeler, Elizabeth A., McConville, Malcolm J., Poulsen, Sally-Ann, Andrews, Katherine T.
Publicado 2020

Antimalarial activity of single-dose DSM265, a novel plasmodium dihydroorotate dehydrogenase inhibitor, in patients with uncomplicated Plasmodium falciparum or Plasmodium vivax mal...

por Llanos-Cuentas, Alejandro, Casapia, Martin, Chuquiyauri, Raúl, Hinojosa, Juan-Carlos, Kerr, Nicola, Rosario, Maria, Toovey, Stephen, Arch, Robert H, Phillips, Margaret A, Rozenberg, Felix D, Bath, Jade, Ng, Caroline L, Cowell, Annie N, Winzeler, Elizabeth A, Fidock, David A, Baker, Mark, Möhrle, Jörg J, Hooft van Huijsduijnen, Rob, Gobeau, Nathalie, Araeipour, Nada, Andenmatten, Nicole, Rückle, Thomas, Duparc, Stephan
Publicado 2018

The Plasmodium falciparum ABC transporter ABCI3 confers parasite strain-dependent pleiotropic antimalarial drug resistance

por Murithi, James M., Deni, Ioanna, Pasaje, Charisse Flerida A., Okombo, John, Bridgford, Jessica L., Gnädig, Nina F., Edwards, Rachel L., Yeo, Tomas, Mok, Sachel, Burkhard, Anna Y., Coburn-Flynn, Olivia, Istvan, Eva S., Sakata-Kato, Tomoyo, Gomez-Lorenzo, Maria G., Cowell, Annie N., Wicht, Kathryn J., Le Manach, Claire, Kalantarov, Gavreel F., Dey, Sumanta, Duffey, Maëlle, Laleu, Benoît, Lukens, Amanda K., Ottilie, Sabine, Vanaerschot, Manu, Trakht, Ilya N., Gamo, Francisco-Javier, Wirth, Dyann F., Goldberg, Daniel E., Odom John, Audrey R., Chibale, Kelly, Winzeler, Elizabeth A., Niles, Jacquin C., Fidock, David A.
Publicado 2022

Mapping the malaria parasite druggable genome by using in vitro evolution and chemogenomics

por Cowell, Annie N., Istvan, Eva S., Lukens, Amanda K., Gomez-Lorenzo, Maria G., Vanaerschot, Manu, Sakata-Kato, Tomoyo, Flannery, Erika L., Magistrado, Pamela, Owen, Edward, Abraham, Matthew, LaMonte, Gregory, Painter, Heather J., Williams, Roy M., Franco, Virginia, Linares, Maria, Arriaga, Ignacio, Bopp, Selina, Corey, Victoria C., Gnädig, Nina F., Coburn-Flynn, Olivia, Reimer, Christin, Gupta, Purva, Murithi, James M., Moura, Pedro A., Fuchs, Olivia, Sasaki, Erika, Kim, Sang W., Teng, Christine H., Wang, Lawrence T., Akidil, Aslı, Adjalley, Sophie, Willis, Paul A., Siege, Dionicio, Tanaseichuk, Olga, Zhong, Yang, Zhou, Yingyao, Llinás, Manuel, Ottilie, Sabine, Gamo, Francisco-Javier, Lee, Marcus C. S., Goldberg, Daniel E., Fidock, David A., Wirth, Dyann F., Winzeler, Elizabeth A.
Publicado 2018