Leptin increasing sympathetic nerve outflow in obesity: A cure for obesity or a potential contributor to metabolic syndrome?

por Simonds, Stephanie E., Cowley, Michael A., Enriori, Pablo J.
Publicado 2012

Dietary Macronutrient Composition Directs ChREBP Isoform Expression and Glucose Metabolism in Mice

por Jois, Tara, Howard, Victor, Youngs, Kristina, Cowley, Michael A., Sleeman, Mark W.
Publicado 2016

Food hypersensitivity-induced chronic gastrointestinal inflammation in a non-human primate model of diet-induced obesity

por Mustafa, Tomris, Li, Qun, Kelly, Lauren E., Gibbon, Anne, Ryan, Irwin, Roffey, Keisha, Simonds, Stephanie, Cowley, Michael A., Sleeman, Mark W.
Publicado 2019

Deletion of hepatic carbohydrate response element binding protein (ChREBP) impairs glucose homeostasis and hepatic insulin sensitivity in mice

por Jois, Tara, Chen, Weiyi, Howard, Victor, Harvey, Rebecca, Youngs, Kristina, Thalmann, Claudia, Saha, Pradip, Chan, Lawrence, Cowley, Michael A., Sleeman, Mark W.
Publicado 2017

SUN-672 SGLT2 Inhibitor Reduces Hyperinsulinemia and Restores Pulsatile Growth Hormone Secretion in Obese MC4RKO Mice

por Huang, Zhengxiang, Huang, Lili, Wang, Chengjian, Zhu, Shanli, Qi, Xinzhou, Chen, Yang, Zhang, Yanjun, Cowley, Michael A, Veldhuis, Johannes D, Chen, Chen
Publicado 2020

Chronic Treatment With a Melanocortin-4 Receptor Agonist Causes Weight Loss, Reduces Insulin Resistance, and Improves Cardiovascular Function in Diet-Induced Obese Rhesus Macaques

por Kievit, Paul, Halem, Heather, Marks, Daniel L., Dong, Jesse Z., Glavas, Maria M., Sinnayah, Puspha, Pranger, Lindsay, Cowley, Michael A., Grove, Kevin L., Culler, Michael D.
Publicado 2013

Plasticity of calcium-permeable AMPA glutamate receptors in Pro-opiomelanocortin neurons

por Suyama, Shigetomo, Ralevski, Alexandra, Liu, Zhong-Wu, Dietrich, Marcelo O, Yada, Toshihiko, Simonds, Stephanie E, Cowley, Michael A, Gao, Xiao-Bing, Diano, Sabrina, Horvath, Tamas L
Publicado 2017

α-MSH Stimulates Glucose Uptake in Mouse Muscle and Phosphorylates Rab-GTPase-Activating Protein TBC1D1 Independently of AMPK

por Møller, Cathrine Laustrup, Kjøbsted, Rasmus, Enriori, Pablo J., Jensen, Thomas Elbenhardt, Garcia-Rudaz, Cecilia, Litwak, Sara A., Raun, Kirsten, Wojtaszewski, Jørgen, Wulff, Birgitte Schjellerup, Cowley, Michael A.
Publicado 2016

Feeding Induced by Cannabinoids Is Mediated Independently of the Melanocortin System

por Sinnayah, Puspha, Jobst, Erin E., Rathner, Joseph A., Caldera-Siu, Angela D., Tonelli-Lemos, Luciana, Eusterbrock, Aaron J., Enriori, Pablo J., Pothos, Emmanuel N., Grove, Kevin L., Cowley, Michael A.
Publicado 2008

Insulin regulates POMC neuronal plasticity to control glucose metabolism

por Dodd, Garron T, Michael, Natalie J, Lee-Young, Robert S, Mangiafico, Salvatore P, Pryor, Jack T, Munder, Astrid C, Simonds, Stephanie E, Brüning, Jens Claus, Zhang, Zhong-Yin, Cowley, Michael A, Andrikopoulos, Sofianos, Horvath, Tamas L, Spanswick, David, Tiganis, Tony
Publicado 2018

The melanocortin pathway and energy homeostasis: From discovery to obesity therapy

por Yeo, Giles S.H., Chao, Daniela Herrera Moro, Siegert, Anna-Maria, Koerperich, Zoe M., Ericson, Mark D., Simonds, Stephanie E., Larson, Courtney M., Luquet, Serge, Clarke, Iain, Sharma, Shubh, Clément, Karine, Cowley, Michael A., Haskell-Luevano, Carrie, Van Der Ploeg, Lex, Adan, Roger A.H.
Publicado 2021

Erratum. Celastrol-Induced Weight Loss Is Driven by Hypophagia and Independent From UCP1. Diabetes 2018;67:2456–2465

por Pfuhlmann, Katrin, Schriever, Sonja C., Baumann, Peter, Kabra, Dhiraj G., Harrison, Luke, Mazibuko-Mbeje, Sithandiwe E., Contreras, Raian E., Kyriakou, Eleni, Simonds, Stephanie E., Tiganis, Tony, Cowley, Michael A., Woods, Stephen C., Jastroch, Martin, Clemmensen, Christoffer, De Angelis, Meri, Schramm, Karl-Werner, Sattler, Michael, Messias, Ana C., Tschöp, Matthias H., Pfluger, Paul T.
Publicado 2019

Leptin Mediates the Increase in Blood Pressure Associated with Obesity

por Simonds, Stephanie E., Pryor, Jack T., Ravussin, Eric, Greenway, Frank L., Dileone, Ralph, Allen, Andrew M., Bassi, Jaspreet, Elmquist, Joel K., Keogh, Julia M., Henning, Elana, Myers, Martin G., Licinio, Julio, Brown, Russell D., Enriori, Pablo J., O’Rahilly, Stephen, Sternson, Scott M., Grove, Kevin L., Spanswick, David C., Farooqi, I. Sadaf, Cowley, Michael A.
Publicado 2014

Reelin is modulated by diet-induced obesity and has direct actions on arcuate proopiomelanocortin neurons

por Roberts, Brandon L., Bennett, Baylin J., Bennett, Camdin M., Carroll, Julie M., Dalbøge, Louise S., Hall, Colin, Hassouneh, Wafa, Heppner, Kristy M., Kirigiti, Melissa A., Lindsley, Sarah R., Tennant, Katherine G., True, Cadence A., Whittle, Andrew, Wolf, Anitra C., Roberts, Charles T., Tang-Christensen, Mads, Sleeman, Mark W., Cowley, Michael A., Grove, Kevin L., Kievit, Paul
Publicado 2019

Coordinated targeting of cold and nicotinic receptors synergistically improves obesity and type 2 diabetes

por Clemmensen, Christoffer, Jall, Sigrid, Kleinert, Maximilian, Quarta, Carmelo, Gruber, Tim, Reber, Josefine, Sachs, Stephan, Fischer, Katrin, Feuchtinger, Annette, Karlas, Angelos, Simonds, Stephanie E., Grandl, Gerald, Loher, Daniela, Sanchez-Quant, Eva, Keipert, Susanne, Jastroch, Martin, Hofmann, Susanna M., Nascimento, Emmani B. M., Schrauwen, Patrick, Ntziachristos, Vasilis, Cowley, Michael A., Finan, Brian, Müller, Timo D., Tschöp, Matthias H.
Publicado 2018

Publisher Correction: Coordinated targeting of cold and nicotinic receptors synergistically improves obesity and type 2 diabetes

por Clemmensen, Christoffer, Jall, Sigrid, Kleinert, Maximilian, Quarta, Carmelo, Gruber, Tim, Reber, Josefine, Sachs, Stephan, Fischer, Katrin, Feuchtinger, Annette, Karlas, Angelos, Simonds, Stephanie E., Grandl, Gerald, Loher, Daniela, Sanchez-Quant, Eva, Keipert, Susanne, Jastroch, Martin, Hofmann, Susanna M., Nascimento, Emmani B. M., Schrauwen, Patrick, Ntziachristos, Vasilis, Cowley, Michael A., Finan, Brian, Müller, Timo D., Tschöp, Matthias H.
Publicado 2018

α-Melanocyte stimulating hormone promotes muscle glucose uptake via melanocortin 5 receptors

por Enriori, Pablo J., Chen, Weiyi, Garcia-Rudaz, Maria C., Grayson, Bernadette E., Evans, Anne E., Comstock, Sarah M., Gebhardt, Ursel, Müller, Hermann L., Reinehr, Thomas, Henry, Belinda A., Brown, Russell D., Bruce, Clinton R., Simonds, Stephanie E., Litwak, Sara A., McGee, Sean L., Luquet, Serge, Martinez, Sarah, Jastroch, Martin, Tschöp, Matthias H., Watt, Matthew J., Clarke, Iain J., Roth, Christian L., Grove, Kevin L., Cowley, Michael A.
Publicado 2016