Ras inhibition boosts galectin-7 at the expense of galectin-1 to sensitize cells to apoptosis

por Barkan, Batya, D. Cox, Adrienne, Kloog, Yoel
Publicado 2013

R-Ras Signals through Specific Integrin α Cytoplasmic Domains to Promote Migration and Invasion of Breast Epithelial Cells

por Keely, Patricia J., Rusyn, Elena V., Cox, Adrienne D., Parise, Leslie V.
Publicado 1999

Scenarios of maternal mortality reduction by 2030 in the Americas: insights from its tempo

por Sanhueza, Antonio, Mujica, Oscar J., Soliz, Patricia N., Cox, Adrienne L., de Mucio, Bremen
Publicado 2023

Src-Mediated Phosphorylation of the Tyrosine Phosphatase PRL-3 Is Required for PRL-3 Promotion of Rho Activation, Motility and Invasion

por Fiordalisi, James J., Dewar, Brian J., Graves, Lee M., Madigan, James P., Cox, Adrienne D.
Publicado 2013

The C. elegans Chp/Wrch Ortholog CHW-1 Contributes to LIN-18/Ryk and LIN-17/Frizzled Signaling in Cell Polarity

por Kidd, Ambrose R., Muñiz-Medina, Vanessa, Der, Channing J., Cox, Adrienne D., Reiner, David J.
Publicado 2015

Differential Requirement of CAAX-mediated Posttranslational Processing for Rheb Localization and Signaling

por Hanker, Ariella B., Mitin, Natalia, Wilder, Rhonda S., Henske, Elizabeth Petri, Tamanoi, Fuyuhiko, Cox, Adrienne D., Der, Channing J.
Publicado 2009

TLN-4601 suppresses growth and induces apoptosis of pancreatic carcinoma cells through inhibition of Ras-ERK MAPK signaling

por Campbell, Paul M, Boufaied, Nadia, Fiordalisi, James J, Cox, Adrienne D, Falardeau, Pierre, Der, Channing J, Gourdeau, Henriette
Publicado 2010

RalA and RalBP1 regulate mitochondrial fission at mitosis

por Kashatus, David F., Lim, Kian-Huat, Brady, Donita C., Pershing, Nicole L.K., Cox, Adrienne D., Counter, Christopher M.
Publicado 2011

Genetic and functional characterization of putative Ras/Raf interaction inhibitors in C. elegans and mammalian cells

por González-Pérez, Vanessa, Reiner, David J, Alan, Jamie K, Mitchell, Cicely, Edwards, Lloyd J, Khazak, Vladimir, Der, Channing J, Cox, Adrienne D
Publicado 2010

Re-sensitization of Mycobacterium smegmatis to Rifampicin Using CRISPR Interference Demonstrates Its Utility for the Study of Non-essential Drug Resistance Traits

por Faulkner, Valwynne, Cox, Adrienne Adele, Goh, Shan, van Bohemen, Annelies, Gibson, Amanda J., Liebster, Oliver, Wren, Brendan W., Willcocks, Sam, Kendall, Sharon L.
Publicado 2021

Engineering threshold-based selection systems

por Pedone, Katherine H, González-Pérez, Vanessa, Leopold, Luciana E, Rasmussen, Neal R, Der, Channing J, Cox, Adrienne D, Ahmed, Shawn, Reiner, David J
Publicado 2021

VCP/p97, a pleiotropic protein regulator of the DNA damage response and proteostasis, is a potential therapeutic target in KRAS-mutant pancreatic cancer

por Lee, Ye S., Klomp, Jennifer E., Stalnecker, Clint A., Goodwin, Craig M., Gao, Yanzhe, Droby, Gaith N., Vaziri, Cyrus, Bryant, Kirsten L., Der, Channing J., Cox, Adrienne D.
Publicado 2023

Pseudomonas aeruginosa utilizes the host-derived polyamine spermidine to facilitate antimicrobial tolerance

por Hasan, Chowdhury M., Pottenger, Sian, Green, Angharad E., Cox, Adrienne A., White, Jack S., Jones, Trevor, Winstanley, Craig, Kadioglu, Aras, Wright, Megan H., Neill, Daniel R., Fothergill, Joanne L.
Publicado 2022

INO80 governs superenhancer-mediated oncogenic transcription and tumor growth in melanoma

por Zhou, Bingying, Wang, Li, Zhang, Shu, Bennett, Brian D., He, Fan, Zhang, Yan, Xiong, Chengliang, Han, Leng, Diao, Lixia, Li, Pishun, Fargo, David C., Cox, Adrienne D., Hu, Guang
Publicado 2016

Data gaps towards health development goals, 47 low- and middle-income countries

por Zhao, Luhua, Cao, Bochen, Borghi, Elaine, Chatterji, Somnath, Garcia-Saiso, Sebastian, Rashidian, Arash, Doctor, Henry Victor, D'Agostino, Marcelo, Karamagi, Humphrey C, Novillo-Ortiz, David, Landry, Mark, Hosseinpoor, Ahmad Reza, Noor, Abdisalan, Riley, Leanne, Cox, Adrienne, Gao, Jun, Litavecz, Steve, Asma, Samira
Publicado 2022

The KRAS-regulated kinome identifies WEE1 and ERK coinhibition as a potential therapeutic strategy in KRAS-mutant pancreatic cancer

por Diehl, J. Nathaniel, Klomp, Jennifer E., Snare, Kayla R., Hibshman, Priya S., Blake, Devon R., Kaiser, Zane D., Gilbert, Thomas S.K., Baldelli, Elisa, Pierobon, Mariaelena, Papke, Björn, Yang, Runying, Hodge, Richard G., Rashid, Naim U., Petricoin, Emanuel F., Herring, Laura E., Graves, Lee M., Cox, Adrienne D., Der, Channing J.
Publicado 2021

Low-Dose Vertical Inhibition of the RAF-MEK-ERK Cascade Causes Apoptotic Death of KRAS Mutant Cancers

por Ozkan-Dagliyan, Irem, Diehl, J. Nathaniel, George, Samuel D., Schaefer, Antje, Papke, Bjoern, Klotz-Noack, Kathleen, Waters, Andrew M., Goodwin, Craig M., Gautam, Prson, Pierobon, Mariaelena, Peng, Sen, Gilbert, Thomas S.K., Lin, Kevin H., Dagliyan, Onur, Wennerberg, Krister, Petricoin, Emanuel F., Tran, Nhan L., Bhagwat, Shripad V., Tiu, Ramon V., Peng, Sheng-Bin, Herring, Laura E., Graves, Lee M., Sers, Christine, Wood, Kris C., Cox, Adrienne D., Der, Channing J.
Publicado 2020

CHK1 protects oncogenic KRAS-expressing cells from DNA damage and is a target for pancreatic cancer treatment

por Klomp, Jennifer E., Lee, Ye S., Goodwin, Craig M., Papke, Björn, Klomp, Jeff A., Waters, Andrew M., Stalnecker, Clint A., DeLiberty, Jonathan M., Drizyte-Miller, Kristina, Yang, Runying, Diehl, J. Nathaniel, Yin, Hongwei H., Pierobon, Mariaelena, Baldelli, Elisa, Ryan, Meagan B., Li, Siqi, Peterson, Jackson, Smith, Amber R., Neal, James T., McCormick, Aaron K., Kuo, Calvin J., Counter, Christopher M., Petricoin, Emanuel F., Cox, Adrienne D., Bryant, Kirsten L., Der, Channing J.
Publicado 2021

Targeting p130Cas- and microtubule-dependent MYC regulation sensitizes pancreatic cancer to ERK MAPK inhibition

por Waters, Andrew M., Khatib, Tala O., Papke, Bjoern, Goodwin, Craig M., Hobbs, G. Aaron, Diehl, J. Nathaniel, Yang, Runying, Edwards, A. Cole, Walsh, Katherine H., Sulahian, Rita, McFarland, James M., Kapner, Kevin S., Gilbert, Thomas S.K., Stalnecker, Clint A., Javaid, Sehrish, Barkovskaya, Anna, Grover, Kajal R., Hibshman, Priya S., Blake, Devon R., Schaefer, Antje, Nowak, Katherine M., Klomp, Jennifer E., Hayes, Tikvah K., Kassner, Michelle, Tang, Nanyun, Tanaseichuk, Olga, Chen, Kaisheng, Zhou, Yingyao, Kalkat, Manpreet, Herring, Laura E., Graves, Lee M., Penn, Linda Z., Yin, Hongwei H., Aguirre, Andrew J., Hahn, William C., Cox, Adrienne D., Der, Channing J.
Publicado 2021