Tether-directed synthesis of highly substituted oxasilacycles via an intramolecular allylation employing allylsilanes

por Jervis, Peter J, Cox, Liam R
Publicado 2007

Synthesis of a Versatile Building Block for the Preparation of 6-N-Derivatized α-Galactosyl Ceramides: Rapid Access to Biologically Active Glycolipids

por Jervis, Peter J., Cox, Liam R., Besra, Gurdyal S.
Publicado 2010

Ppm1-Encoded Polyprenyl Monophosphomannose Synthase Activity Is Essential for Lipoglycan Synthesis and Survival in Mycobacteria

por Rana, Amrita K., Singh, Albel, Gurcha, Sudagar S., Cox, Liam R., Bhatt, Apoorva, Besra, Gurdyal S.
Publicado 2012

Endoplasmic Reticulum Glycoprotein Quality Control Regulates CD1d Assembly and CD1d-mediated Antigen Presentation

por Kunte, Amit, Zhang, Wei, Paduraru, Crina, Veerapen, Natacha, Cox, Liam R., Besra, Gurdyal S., Cresswell, Peter
Publicado 2013

Synthesis and biological activity of α-glucosyl C24:0 and C20:2 ceramides

por Jervis, Peter J., Veerapen, Natacha, Bricard, Gabriel, Cox, Liam R., Porcelli, Steven A., Besra, Gurdyal S.
Publicado 2010

Synthesis and biological activity of α-galactosyl ceramide KRN7000 and galactosyl (α1→2) galactosyl ceramide

por Veerapen, Natacha, Brigl, Manfred, Garg, Salil, Cerundolo, Vincenzo, Cox, Liam R., Brenner, Michael B., Besra, Gurdyal S.
Publicado 2009

Amide Analogues of CD1d Agonists Modulate iNKT-Cell-Mediated Cytokine Production

por Wojno, Justyna, Jukes, John-Paul, Ghadbane, Hemza, Shepherd, Dawn, Besra, Gurdyal S., Cerundolo, Vincenzo, Cox, Liam R.
Publicado 2012

New CD1d agonists: Synthesis and biological activity of 6″-triazole-substituted α-galactosyl ceramides

por Jervis, Peter J., Graham, Lisa M., Foster, Erin L., Cox, Liam R., Porcelli, Steven A., Besra, Gurdyal S.
Publicado 2012

Towards multivalent CD1d ligands: synthesis and biological activity of homodimeric α-galactosyl ceramide analogues

por Jervis, Peter J., Moulis, Marie, Jukes, John-Paul, Ghadbane, Hemza, Cox, Liam R., Cerundolo, Vincenzo, Besra, Gurdyal S.
Publicado 2012

Disruption of the serine/threonine protein kinase H affects phthiocerol dimycocerosates synthesis in Mycobacterium tuberculosis

por Gómez-Velasco, Anaximandro, Bach, Horacio, Rana, Amrita K., Cox, Liam R., Bhatt, Apoorva, Besra, Gurdyal S., Av-Gay, Yossef
Publicado 2013

CD1d‐mediated activation of group 3 innate lymphoid cells drives IL‐22 production

por Saez de Guinoa, Julia, Jimeno, Rebeca, Farhadi, Nazanin, Jervis, Peter J, Cox, Liam R, Besra, Gurdyal S, Barral, Patricia
Publicado 2016

Non‐glycosidic compounds can stimulate both human and mouse iNKT cells

por Jukes, John‐Paul, Gileadi, Uzi, Ghadbane, Hemza, Yu, Ting‐Fong, Shepherd, Dawn, Cox, Liam R., Besra, Gurdyal S., Cerundolo, Vincenzo
Publicado 2016

Design, Synthesis, and Functional Activity of Labeled CD1d Glycolipid Agonists

por Jervis, Peter J., Polzella, Paolo, Wojno, Justyna, Jukes, John-Paul, Ghadbane, Hemza, Garcia Diaz, Yoel R., Besra, Gurdyal S., Cerundolo, Vincenzo, Cox, Liam R.
Publicado 2013

The multi-target aspect of an MmpL3 inhibitor: The BM212 series of compounds bind EthR2, a transcriptional regulator of ethionamide activation

por Moorey, Alice R., Cabanillas, Alejandro, Batt, Sarah M., Ghidelli-Disse, Sonja, Urones, Beatriz, Sanz, Olalla, Lelievre, Joel, Bantscheff, Marcus, Cox, Liam R., Besra, Gurdyal S.
Publicado 2021

Assay development and inhibition of the Mt-DprE2 essential reductase from Mycobacterium tuberculosis

por Batt, Sarah M., Toth, Szilvi, Rodriguez, Beatriz, Abrahams, Katherine A., Veerapen, Natacha, Chiodarelli, Giacomo, Cox, Liam R., Moynihan, Patrick J., Lelievre, Joel, Fütterer, Klaus, Besra, Gurdyal S.
Publicado 2023

Identification and characterization of aspartyl-tRNA synthetase inhibitors against Mycobacterium tuberculosis by an integrated whole-cell target-based approach

por Soto, Ramón, Perez-Herran, Esther, Rodriguez, Beatriz, Duma, Bogdan M., Cacho-Izquierdo, Monica, Mendoza-Losana, Alfonso, Lelievre, Joel, Aguirre, David Barros, Ballell, Lluis, Cox, Liam R., Alderwick, Luke J., Besra, Gurdyal S.
Publicado 2018

Influence of the Lipid Backbone on Electrochemical Phase Behavior

por Jemmett, Philip N., Milan, David C., Nichols, Richard J., Howitt, Thomas, Martin, Alexandra L., Arnold, Thomas, Rawle, Jonathan L., Nicklin, Christopher L., Dafforn, Timothy R., Cox, Liam R., Horswell, Sarah L.
Publicado 2022

Ligand-dependent downregulation of MR1 cell surface expression

por Salio, Mariolina, Awad, Wael, Veerapen, Natacha, Gonzalez-Lopez, Claudia, Kulicke, Corinna, Waithe, Dominic, Martens, Anne W. J., Lewinsohn, David M., Hobrath, Judith V., Cox, Liam R., Rossjohn, Jamie, Besra, Gurdyal S., Cerundolo, Vincenzo
Publicado 2020

OR28-03 Drug Repurposing Identifies Inhibitors of the Proteostasis Network to Augment Radioiodine Uptake in Combinatorial Approaches Targeting Thyroid Cancer

por Read, Martin L, Brookes, Katie, Fletcher, Alice, Thornton, Caitlin E M, Alshahrani, Mohammed, Khan, Rashida, Nieto, Hannah R, Adcock, Holly V, Webster, Jamie R M, Cox, Liam, Alderwick, Luke J, Boelaert, Kristien, Smith, Vicki E, McCabe, Christopher J
Publicado 2020

Effect of Anionic Lipids on Mammalian Plasma Cell Membrane Properties

por Martin, Alexandra L., Jemmett, Philip N., Howitt, Thomas, Wood, Mary H., Burley, Andrew W., Cox, Liam R., Dafforn, Timothy R., Welbourn, Rebecca J. L., Campana, Mario, Skoda, Maximilian W. A., Thompson, Joseph J., Hussain, Hadeel, Rawle, Jonathan L., Carlà, Francesco, Nicklin, Christopher L., Arnold, Thomas, Horswell, Sarah L.
Publicado 2023